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Template:Transient receptor potential channel modulators - Revision history
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Richardpruen
https://safernicotine.wiki/mediawiki/index.php?title=Template:Transient_receptor_potential_channel_modulators&diff=7969&oldid=prev
Wikipedia>Meodipt at 09:39, 14 February 2021
2021-02-14T09:39:11Z
<p></p>
<p><b>New page</b></p><div>{{Navbox<br />
| name = Transient receptor potential channel modulators<br />
| title = [[Transient receptor potential channel|{{abbr|TRP|Transient receptor potential}} channel]] [[Channel modulator|modulator]]s<br />
| state = {{{state<includeonly>|collapsed</includeonly>}}}<br />
| listclass = hlist<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = {{abbr|[[TRPA (ion channel)|TRPA]]|Transient receptor potential ankyrin channel}}<!--TRPA1, unless otherwise specified--><br />
| list1 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = Activators<br />
| list1 = <br />
* [[4-Hydroxynonenal]]<br />
* [[4-Oxo-2-nonenal]]<br />
* [[Epoxyeicosatrienoic acid|4,5-EET]]<!--4,5-Epoxy-8Z,11Z,14Z-eicosatrienoic acid--><br />
* [[Epoxyeicosatrienoic acid|12S-HpETE]]<!--12S-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid--><br />
* [[Cyclopentenone prostaglandins|15-Deoxy-Δ<sup>12,14</sup>-prostaglandin J2]]<br />
* [[Hydroxy alpha sanshool|α-Sanshool]] ([[ginger]], [[Sichuan pepper|Sichuan]] and [[Aframomum melegueta|melegueta pepper]]s)<br />
* [[Acrolein]]<br />
* [[Allicin]] ([[garlic]])<br />
* [[Allyl isothiocyanate]] ([[mustard plant|mustard]], [[radish]], [[horseradish]], [[wasabi]])<br />
* [[AM404]]<br />
* [[ASP-7663]]<br />
* [[Bradykinin]]<br />
* [[Cannabichromene]] ([[cannabis]])<br />
* [[Cannabidiol]] ([[cannabis]])<br />
* [[Cannabigerol]] ([[cannabis]])<br />
* [[Cinnamaldehyde]] ([[cinnamon]])<br />
* [[CR gas|CR gas (dibenzoxazepine; DBO)]]<br />
* [[CS gas|CS gas (2-chlorobenzal malononitrile)]]<br />
* [[Cuminaldehyde]] ([[cumin]])<br />
* [[Curcumin]] ([[turmeric]])<br />
* [[Dehydroligustilide]] ([[celery]])<!--bimodal--><br />
* [[Diallyl disulfide]]<br />
* [[Dicentrine]] (''[[Lindera]]'' spp.)<br />
* [[Farnesyl thiosalicylic acid]]<br />
* [[Formalin]]<br />
* [[Gingerol]]s ([[ginger]])<br />
* [[Hepoxilin A3]]<!--8R/S-Hydroxy-11,12-oxido-5Z,9E,14Z-eicosatrienoic acid--><br />
* [[Hepoxilin B3]]<!--10R/S-Hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid--><br />
* [[Hydrogen peroxide]]<br />
* [[Icilin]]<br />
* [[Isothiocyanate]]<br />
* [[JT-010]]<br />
* [[Ligustilide]] ([[celery]], ''[[Angelica acutiloba]]'')<br />
* [[Linalool]] ([[Sichuan pepper]], [[thyme]])<br />
* [[Methylglyoxal]]<br />
* [[Methyl salicylate]] ([[wintergreen]])<br />
* [[N-Methylmaleimide]]<br />
* [[Nicotine]] ([[tobacco]])<br />
* [[Oleocanthal]] ([[olive oil]])<br />
* [[Paclitaxel]] ([[Taxus brevifolia|Pacific yew]])<br />
* [[Paracetamol|Paracetamol (acetaminophen)]]<br />
* [[PF-4840154]]<br />
* [[Phenacyl chloride]]<br />
* [[Polygodial]] ([[Tasmannia stipitata|Dorrigo pepper]])<br />
* [[Shogaol]]s ([[ginger]], [[Sichuan pepper|Sichuan]] and [[Aframomum melegueta|melegueta pepper]]s)<br />
* [[Tear gas]]es<br />
* [[Tetrahydrocannabinol]] ([[cannabis]])<br />
* [[Tetrahydrocannabiorcol]]<br />
* [[Syn-Propanethial-S-oxide|Thiopropanal S-oxide]] ([[onion]])<br />
* [[Umbellulone]] (''Umbellularia californica'')<br />
* [[WIN 55,212-2]]<br />
<br />
| group2 = Blockers<br />
| list2 = <br />
* [[A-967079]]<br />
* [[AM-0902]]<br />
* [[Dehydroligustilide]] ([[celery]])<!--bimodal--><br />
* [[HC-030031]]<br />
* [[Nicotine]] ([[tobacco]])<!--bimodal--><br />
* [[PF-04745637]]<br />
* [[Ruthenium red]]<br />
<br />
}}<br />
<br />
| group2 = {{abbr|[[TRPC]]|Transient receptor potential canonical channel}}<br />
| list2 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = Activators<br />
| list1 = <br />
* [[Adhyperforin]] ([[Hypericum perforatum|St John's wort]])<!--TRPC6--><br />
* [[Diglyceride|Diacyl glycerol]]<!--TRPC3, TRPC6, and TRPC7--><br />
* [[GSK1702934A]]<!--TRPC3--><br />
* [[Hyperforin]] ([[Hypericum perforatum|St John's wort]])<!--TRPC6--><br />
* [[Substance P]]<!--TRPC3, TRPC7--><br />
<br />
| group2 = Blockers<br />
| list2 = <br />
* [[3′-5-Dichlorodiphenylamine-2-carboxylic acid|DCDPC]]<!--TRPC6--><br />
* [[Dehydroepiandrosterone sulfate|DHEA-S]]<!--TRPC5--><br />
* [[Flufenamic acid]]<!--TRPC6--><br />
* [[GSK417651A]]<!--TRPC3--><br />
* [[GSK2293017A]]<!--TRPC3--><br />
* [[Meclofenamic acid]]<!--TRPC6--><br />
* [[N-(p-Amylcinnamoyl)anthranilic acid]]<!--TRPC6--><br />
* [[Niflumic acid]]<!--TRPC6--><br />
* [[Pregnenolone sulfate]]<!--TRPC5--><br />
* [[Progesterone]]<!--TRPC5--><br />
* [[Pyr3]]<!--TRPC3--><br />
* [[Tolfenamic acid]]<!--TRPC6--><br />
<br />
}}<br />
<br />
| group3 = {{abbr|[[TRPM]]|Transient receptor potential melastatin channel}}<br />
| list3 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = Activators<br />
| list1 = <br />
* [[Adenosine diphosphate ribose|ADP-ribose]]<!--TRPM2--><br />
* [[BCTC (drug)|BCTC]]<!--TRPM8--><br />
* [[Calcium]] (intracellular)<!--TRPM4, TRPM5--><br />
* [[CIM-0216]]<!--TRPM3--><br />
* [[Cold]]<!--TRPM8--><br />
* [[Coolact P]]<!--TRPM8--><br />
* [[Cooling Agent 10]]<!--TRPM8--><br />
* [[Eucalyptol]] ([[eucalyptus]])<!--TRPM8--><br />
* [[Frescolat MGA]]<!--TRPM8--><br />
* [[Frescolat ML]]<!--TRPM8--><br />
* [[Geraniol]]<!--TRPM8--><br />
* [[Hydroxycitronellal]]<!--TRPM8--><br />
* [[Icilin]]<!--TRPM8--><br />
* [[Linalool]]<!--TRPM8--><br />
* [[Menthol]] ([[Mentha|mint]])<!--TRPM8--><br />
* [[PMD 38]]<!--TRPM8--><br />
* [[Pregnenolone sulfate]]<!--TRPM3--><br />
* [[Rutamarin]] (''[[Ruta graveolens]]'')<!--TRPM5--><br />
* [[Steviol glycoside]]s (e.g., [[stevioside]]) (''[[Stevia rebaudiana]]'')<!--TRPM5--><br />
* Sweet [[taste|tastant]]s (e.g., [[glucose]], [[fructose]], [[sucrose]]; indirectly)<!--TRPM5--><br />
* [[Thio-BCTC]]<!--TRPM8--><br />
* [[WS-12]]<!--TRPM8--><br />
<br />
| group2 = Blockers<br />
| list2 = <br />
* [[AMG-333]]<!--TRPM8--><br />
* [[Capsazepine]]<!--TRPM8--><br />
* [[Clotrimazole]]<!--TRPM5--><br />
* [[3′-5-Dichlorodiphenylamine-2-carboxylic acid|DCDPC]]<!--TRPM2, TRPM3--><br />
* [[Elismetrep]]<!--TRPM8--><br />
* [[Flufenamic acid]]<!--TRPM2, TRPM3, TRPM4, TRPM5--><br />
* [[Meclofenamic acid]]<!--TRPM2, TRPM3--><br />
* [[Mefenamic acid]]<!--Selective for TRPM3 only--><br />
* [[N-(p-Amylcinnamoyl)anthranilic acid]]<!--TRPM2, TRPM8--><br />
* [[Nicotine]] ([[tobacco]])<!--TRPM5--><br />
* [[Niflumic acid]]<!--TRPM3--><br />
* [[Ononetin]]<br />
* [[PF-05105679]]<!--TRPM8--><br />
* [[RQ-00203078]]<!--TRPM8--><br />
* [[Ruthenium red]]<!--TRPM6, TRPM8--><br />
* [[Rutamarin]] (''[[Ruta graveolens]]'')<!--TRPM8--><br />
* [[Tolfenamic acid]]<!--TRPM2, TRPM3--><br />
* [[Triphenylphosphine oxide|TPPO]]<!--TRPM5--><br />
* [[TRPM4-IN-5]]<!--TRPM4--><br />
<br />
}}<br />
<br />
| group4 = {{abbr|[[TRPML]]|Transient receptor potential mucolipin channel}}<br />
| list4 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = Activators<br />
| list1 = <br />
* [[EVP21]]<br />
* [[MK6-83]]<!--5-methyl-N-(2-piperidin-1-ylphenyl)thiophene-2-sulphonamide--><br />
* [[ML-SA1]]<br />
* [[ML2-SA1]]<br />
* [[Phosphatidylinositol 3,5-bisphosphate|PI(3,5)P<sub>2</sub>]]<br />
* [[SF-22]]<!--5-chloro-N-(2-piperidin-1-ylphenyl)thiophene-2-sulphonamide--><br />
* [[SN-2]]<br />
<br />
| group2 = Blockers<br />
| list2 = <br />
* [[ML-SI3]]<br />
* [[Phosphatidylinositol 4,5-bisphosphate|PI(4,5)P<sub>2</sub>]]<br />
}}<br />
<br />
| group6 = {{abbr|[[TRPP]]|Transient receptor potential polycystin channel}}<br />
| list6 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = Activators<br />
| list1 = <br />
* [[Triptolide]] (''[[Tripterygium wilfordii]]'')<br />
<br />
| group2 = Blockers<br />
| list2 = <br />
* [[Ruthenium red]]<!--TRPP3--><br />
<br />
}}<br />
<br />
| group7 = {{abbr|[[TRPV]]|Transient receptor potential vanilloid channel}}<!--TRPV1, unless otherwise specified--><br />
| list7 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = Activators<br />
| list1 = <br />
* [[2-Aminoethoxydiphenyl borate|2-APB]]<!--TRPV1, TRPV2, and TRPV3--><br />
* [[Epoxyeicosatrienoic acid|5',6'-EET]]<!--TRPV4--><br />
* [[9-Hydroxyoctadecadienoic acid|9-HODE]]<!--9(S/R)-Hydroxy-10(E),12(Z)-octadecadienoic acid--><br />
* [[9-Hydroxyoctadecadienoic acid|9-oxoODE]]<br />
* [[Epoxyeicosatrienoic acid|12S-HETE]]<!--12S-Hydroxy-5Z,8Z,10E,12S,14Z-eicosatetraenoic acid--><br />
* [[Epoxyeicosatrienoic acid|12S-HpETE]]<!--12S-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid--><br />
* [[13-Hydroxyoctadecadienoic acid|13-HODE]]<!--13(S/R)-Hydroxy-9Z,11E-octadecadienoic acid--><br />
* [[13-Hydroxyoctadecadienoic acid|13-oxoODE]]<br />
* [[20-Hydroxyeicosatetraenoic acid|20-HETE]]<!--20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid--><br />
* [[Hydroxy alpha sanshool|α-Sanshool]] ([[ginger]], [[Sichuan pepper|Sichuan]] and [[Aframomum melegueta|melegueta pepper]]s)<br />
* [[Allicin]] ([[garlic]])<br />
* [[AM404]]<br />
* [[Anandamide]]<br />
* [[Bisandrographolide]] (''[[Andrographis paniculata]]'')<!--TRPV4, not TRPV1, TRPV2, or TRPV3--><br />
* [[Camphor]] ([[Cinnamomum camphora|camphor laurel]], [[rosemary]], [[camphorweed]], [[African blue basil]], [[Ocimum kilimandscharicum|camphor basil]])<!--TRPV1 and TRPV3--><br />
* [[Cannabidiol]] ([[cannabis]])<!--TRPV1, TRPV2, and TRPV3--><br />
* [[Cannabidivarin]] ([[cannabis]])<!--TRPV4--><br />
* [[Capsaicin]] ([[chili pepper]])<br />
* [[Carvacrol]] ([[oregano]], [[thyme]], [[Lepidium|pepperwort]], [[Monarda fistulosa|wild bergamot]], others)<!--TRPV1 and TRPV3--><br />
* [[Dehydroepiandrosterone|DHEA]]<br />
* [[Diglyceride|Diacyl glycerol]]<!--TRPV4--><br />
* [[Dihydrocapsaicin]] ([[chili pepper]])<br />
* [[Estradiol]]<!--TRPV1--><br />
* [[Eugenol]] ([[basil]], [[clove]])<!--TRPV1 and TRPV3--><br />
* [[Evodiamine]] (''[[Tetradium ruticarpum|Euodia ruticarpa]]'')<br />
* [[Gingerol]]s ([[ginger]])<br />
* [[GSK1016790A]]<!--TRPV1, TRPV4--><br />
* [[Heat]]<!--TRPV1, TRPV3, TRPV4--><br />
* [[Hepoxilin A3]]<!--8R/S-Hydroxy-11,12-oxido-5Z,9E,14Z-eicosatrienoic acid--><br />
* [[Hepoxilin B3]]<!--10R/S-Hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid--><br />
* [[Homocapsaicin]] ([[chili pepper]])<br />
* [[Homodihydrocapsaicin]] ([[chili pepper]])<br />
* [[Incensole]] ([[incense]])<!--TRPV3, not TRPV1--><br />
* [[Lysophosphatidic acid]]<br />
* Low [[pH]] (acidic conditions)<br />
* [[Menthol]] ([[Mentha|mint]])<!--TRPV3, not TRPV1--><br />
* [[N-Arachidonoyl dopamine]]<br />
* [[N-Oleoyldopamine]]<br />
* [[Oleoylethanolamide|N-Oleoylethanolamide]]<br />
* [[Nonivamide|Nonivamide (PAVA)]] ([[PAVA spray]])<br />
* [[Nordihydrocapsaicin]] ([[chili pepper]])<br />
* [[Paclitaxel]] ([[Taxus brevifolia|Pacific yew]])<!--TRPV4, not TRPV1--><br />
* [[Paracetamol|Paracetamol (acetaminophen)]]<br />
* [[Phenylacetylrinvanil]]<br />
* [[Phorbol esters]] (e.g., [[4α-phorbol 12,13-didecanoate|4α-PDD]])<!--TRPV4--><br />
* [[Piperine]] ([[black pepper]], [[long pepper]])<br />
* [[Polygodial]] ([[Tasmannia stipitata|Dorrigo pepper]])<br />
* [[Probenecid]]<!--TRPV2--><br />
* [[Proton]]s<br />
* [[RhTx]]<br />
* [[Rutamarin]] (''[[Ruta graveolens]]'')<br />
* [[Resiniferatoxin]] (RTX) (''[[Euphorbia resinifera]]/[[Euphorbia poissonii|pooissonii]]'')<br />
* [[Shogaol]]s ([[ginger]], [[Sichuan pepper|Sichuan]] and [[Aframomum melegueta|melegueta pepper]]s)<br />
* [[Tetrahydrocannabivarin]] ([[cannabis]])<!--TRPV3, TRPV4--><br />
* [[Thymol]] ([[thyme]], [[oregano]])<!--TRPV1 and TRPV3--><br />
* [[Tinyatoxin]] (''[[Euphorbia resinifera]]/[[Euphorbia poissonii|pooissonii]]'')<br />
* [[Tramadol]]<br />
* [[Vanillin]] ([[vanilla]])<!--TRPV1 and TRPV3--><br />
* [[Zucapsaicin]]<br />
<br />
| group2 = Blockers<br />
| list2 = <br />
* [[Spinasterol|α-Spinasterol]] (''[[Vernonia|Vernonia tweediana]]'')<!--TRPV1--><br />
* [[AMG-517]]<!--TRPV1--><br />
* [[AMG-9810]]<br />
* [[Asivatrep]]<!--TRPV1--><br />
* [[BCTC (drug)|BCTC]]<!--TRPV1--><br />
* [[Cannabigerol]] ([[cannabis]])<!--TRPV4--><br />
* [[Cannabigerolic acid]] ([[cannabis]])<!--TRPV3, TRPV4--><br />
* [[Cannabigerovarin]] ([[cannabis]])<!--TRPV3, TRPV4--><br />
* [[Cannabinol]] ([[cannabis]])<!--TRPV4--><br />
* [[Capsazepine]]<!--TRPV1--><br />
* [[3′-5-Dichlorodiphenylamine-2-carboxylic acid|DCDPC]]<!--TRPV4--><br />
* [[Dehydroepiandrosterone|DHEA]]<!--TRPV1--><br />
* [[Dehydroepiandrosterone sulfate|DHEA-S]]<!--TRPV1--><br />
* [[Flufenamic acid]]<!--TRPV4--><br />
* [[GRC-6211]]<br />
* [[HC-067047]]<!--TRPV4--><br />
* [[Lanthanum]]<!--TRPV2--><br />
* [[Mavatrep]]<!--TRPV1--><br />
* [[Meclofenamic acid]]<!--TRPV4--><br />
* [[N-(p-Amylcinnamoyl)anthranilic acid]]<!--TRPV1--><br />
* [[NGD-8243]]<!--TRPV1--><br />
* [[Niflumic acid]]<!--TRPV4--><br />
* [[Pregnenolone sulfate]]<!--TRPV1--><br />
* [[RN-1734]]<!--TRPV4--><br />
* [[RN-9893]]<!--TRPV4--><br />
* [[Ruthenium red]]<!--TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6--><br />
* [[SB-705498]]<!--TRPV1--><br />
* [[Tivanisiran]]<!--TRPV1--><br />
* [[Tolfenamic acid]]<!--TRPV4--><br />
* [[TRPV3-74a]]<!--TRPV3--><br />
<br />
}}<br />
<br />
| below = '''''See also:''' [[Template:Receptor modulators|Receptor/signaling modulators]] • [[Template:Ion channel modulators|Ion channel modulators]]''<br />
<br />
}}<noinclude><br />
{{Documentation}}<br />
</noinclude></div>
Wikipedia>Meodipt