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- Nicotine therapeutic benefits (section 2014 The Experimental Autoimmune Encephalomyelitis Disease Course Is Modulated by Nicotine and Other Cigarette Smoke Components)revealed nicotine's potential as a UPS and autophagy activator to prevent PD and other neurodegenerative diseases. Note: highly technical brain biochemistry...327 KB (39,289 words) - 16:55, 12 July 2025