| Line 267: | Line 267: | ||
*"The study provides zero evidence on any risk associated with e-cigarette use, whether absolute risk or in comparison with smoking. The question that was supposed to be addressed in this metanalysis CANNOT be examined with the studies included in their analysis." (Farsalinos) | *"The study provides zero evidence on any risk associated with e-cigarette use, whether absolute risk or in comparison with smoking. The question that was supposed to be addressed in this metanalysis CANNOT be examined with the studies included in their analysis." (Farsalinos) | ||
*[https://pubpeer.com/publications/9E38A75C420D1F19DA0D48C37FA8D8 See Also]: "The methods look impressive, but the devil is in the dirty details buried in the nearly 100 pages supplemental material. The authors have done an admirable job collecting studies and organizing them, but the conclusions reached are untenable, and unsupportable at least for now." (Cummings) | *[https://pubpeer.com/publications/9E38A75C420D1F19DA0D48C37FA8D8 See Also]: "The methods look impressive, but the devil is in the dirty details buried in the nearly 100 pages supplemental material. The authors have done an admirable job collecting studies and organizing them, but the conclusions reached are untenable, and unsupportable at least for now." (Cummings) | ||
*Referring to: Glantz SA, Nguyen N, Oliveira da Silva AL. Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes. NEJM Evid. 2024 Mar;3(3):EVIDoa2300229. Epub 2024 Feb 27. PMID: 38411454. [https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300229 doi: 10.1056/EVIDoa2300229] | **Referring to: Glantz SA, Nguyen N, Oliveira da Silva AL. Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes. NEJM Evid. 2024 Mar;3(3):EVIDoa2300229. Epub 2024 Feb 27. PMID: 38411454. [https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300229 doi: 10.1056/EVIDoa2300229] | ||
===2022: Comments RE: [https://colinmendelsohn.com.au/wp-content/uploads/2022/07/Mendelsohn-Wodak-Hall-Borland.-A-critical-analysis-of-Ecigs-and-health-outcomes-systematic-review-of-global-evidence.-DAR-2022.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]=== | ===2022: Comments RE: [https://colinmendelsohn.com.au/wp-content/uploads/2022/07/Mendelsohn-Wodak-Hall-Borland.-A-critical-analysis-of-Ecigs-and-health-outcomes-systematic-review-of-global-evidence.-DAR-2022.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]=== | ||
*Contrary to the conclusions of the Banks review, the evidence suggests that vaping nicotine is an effective smoking cessation aid; that vaping is substantially less harmful than smoking tobacco; that vaping is diverting young people away from smoking; and that vaping by smokers is likely to have a major net public health benefit if widely available to adult Australian smokers. (Mendelsohn) | *Contrary to the conclusions of the Banks review, the evidence suggests that vaping nicotine is an effective smoking cessation aid; that vaping is substantially less harmful than smoking tobacco; that vaping is diverting young people away from smoking; and that vaping by smokers is likely to have a major net public health benefit if widely available to adult Australian smokers. (Mendelsohn) | ||
*Referring to: Banks E, Yazidjoglou A, Brown S, Nguyen M, Martin M, Beckwith K, Daluwatta A, Campbell S, Joshy G. [https://www.nhmrc.gov.au/sites/default/files/documents/attachments/ecigarettes/Electronic_cigarettes_and_health_outcomes_%20systematic_review_of_evidence.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]. Report for the Australian Department of Health. National Centre for Epidemiology and Population Health, Canberra: April 2022. | **Referring to: Banks E, Yazidjoglou A, Brown S, Nguyen M, Martin M, Beckwith K, Daluwatta A, Campbell S, Joshy G. [https://www.nhmrc.gov.au/sites/default/files/documents/attachments/ecigarettes/Electronic_cigarettes_and_health_outcomes_%20systematic_review_of_evidence.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]. Report for the Australian Department of Health. National Centre for Epidemiology and Population Health, Canberra: April 2022. | ||
===2022: Comments RE: [https://pubpeer.com/publications/727EA7B64FB27270F20717729D7629 Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice]=== | ===2022: Comments RE: [https://pubpeer.com/publications/727EA7B64FB27270F20717729D7629 Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice]=== | ||
*Although this new research from Moshensky et al., does add to the scientific literature about previously marketed JUUL products, we believe the conclusions presented in the manuscript are not adequately supported by the study data. In addition, the lack of quantitative data on actual dosing limits the ability to establish relevance to potential human exposures from product use. Furthermore, the lack of a comparison against the effects of tobacco smoke limits the ability to evaluate these study findings in the context of the tobacco product risk continuum, and risk relative to use of combusted cigarettes. (Weil) | *Although this new research from Moshensky et al., does add to the scientific literature about previously marketed JUUL products, we believe the conclusions presented in the manuscript are not adequately supported by the study data. In addition, the lack of quantitative data on actual dosing limits the ability to establish relevance to potential human exposures from product use. Furthermore, the lack of a comparison against the effects of tobacco smoke limits the ability to evaluate these study findings in the context of the tobacco product risk continuum, and risk relative to use of combusted cigarettes. (Weil) | ||
*Referring to: Moshensky A, Brand CS, Alhaddad H, Shin J, Masso-Silva JA, Advani I, Gunge D, Sharma A, Mehta S, Jahan A, Nilaad S, Olay J, Gu W, Simonson T, Almarghalani D, Pham J, Perera S, Park K, Al-Kolla R, Moon H, Das S, Byun MK, Shah Z, Sari Y, Heller Brown J, Crotty Alexander LE. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. Elife. 2022 Apr 12;11:e67621. PMID: 35411847; PMCID: PMC9005188. [https://doi.org/10.7554/elife.67621 doi: 10.7554/eLife.67621] | **Referring to: Moshensky A, Brand CS, Alhaddad H, Shin J, Masso-Silva JA, Advani I, Gunge D, Sharma A, Mehta S, Jahan A, Nilaad S, Olay J, Gu W, Simonson T, Almarghalani D, Pham J, Perera S, Park K, Al-Kolla R, Moon H, Das S, Byun MK, Shah Z, Sari Y, Heller Brown J, Crotty Alexander LE. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. Elife. 2022 Apr 12;11:e67621. PMID: 35411847; PMCID: PMC9005188. [https://doi.org/10.7554/elife.67621 doi: 10.7554/eLife.67621] | ||
===2018: Comments RE: [https://www.sciencemediacentre.org/expert-reaction-to-modelling-study-on-electronic-cigarettes-in-the-us/ Quantifying population-level health benefits and harms of e-cigarette use in the United States]=== | |||
*"The authors make some very speculative assumptions here, particularly on the ‘gateway’ effect in teenagers – they assume that vaping leads to smoking. The trouble is, all their data on this comes from studies that don’t prove anything of the sort...The authors’ estimate of ‘life years lost’ is primarily driven by their overestimate of e-cig use contributing to a significant increase in the uptake of smoking in kids." (Shahab) | |||
*"This new ‘finding’ is based on the bizarre assumption that for every one smoker who uses e-cigs to quit, 80 non-smokers will try e-cigs and take up smoking. It flies in the face of available evidence but it is also mathematically impossible." (Hajek) | |||
**Referring to: Soneji SS, Sung HY, Primack BA, Pierce JP, Sargent JD. Quantifying population-level health benefits and harms of e-cigarette use in the United States. PLoS One. 2018 Mar 14;13(3):e0193328. [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193328 doi: 10.1371/journal.pone.0193328]. PMID: 29538396; PMCID: PMC5851558. | |||
==Respiratory== | ==Respiratory== | ||
edits