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='''HnB / HTP'''= | ='''HnB / HTP'''= | ||
===2024: [https://www.sciencedirect.com/science/article/pii/S2405844024001154 E-cigarettes and heated tobacco products impact on dental color parameters]=== | ===2024: [https://www.sciencedirect.com/science/article/pii/S2405844024001154 E-cigarettes and heated tobacco products impact on dental color parameters]=== | ||
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*Conventional cigarette and heated tobacco product smoke can change the color of denture teeth. Heated tobacco product smoke causes less discoloration of denture teeth. | *Conventional cigarette and heated tobacco product smoke can change the color of denture teeth. Heated tobacco product smoke causes less discoloration of denture teeth. | ||
*Citation: | *Citation: | ||
===2021: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371723/ Impact of exclusive e-cigarettes and heated tobacco products use on muco-ciliary clearance]=== | |||
*Former smokers who have switched to exclusive regular use of combustion-free nicotine delivery systems (i.e., ECs and HTPs) exhibit similar saccharin transit time as never and former smokers. This suggests that combustion-free nicotine delivery technologies are unlikely to have detrimental effects on MCC function. Former smokers who have switched to exclusive regular use of combustion-free nicotine delivery systems (i.e., ECs and HTPs) exhibit similar saccharin transit time as never and former smokers. This suggests that combustion-free nicotine delivery technologies are unlikely to have detrimental effects on MCC function. | |||
*Citation: Polosa R, Emma R, Cibella F, Caruso M, Conte G, Benfatto F, Ferlito S, Gulino A, Malerba M, Caponnetto P. Impact of exclusive e-cigarettes and heated tobacco products use on muco-ciliary clearance. Ther Adv Chronic Dis. 2021 Aug 12;12:20406223211035267. doi: 10.1177/20406223211035267. PMID: 34422253; PMCID: PMC8371723. | |||
===2020: [https://link.springer.com/article/10.1007/s00204-020-02924-x Cancer potencies and margin of exposure used for comparative risk assessment of heated tobacco products and electronic cigarettes aerosols with cigarette smoke]=== | |||
*Even if they should not be considered as risk-free products, HTPs and ECs lead to an appreciable risk reduction in comparison to cigarettes, both for cancer and non-cancer diseases. According to the current knowledge, and more specifically to the data presented here, HTPs and ECs might be considered as an acceptable reduced risk substitute for cigarettes for legal-age smokers who would otherwise continue smoking cigarettes. | |||
*[https://link.springer.com/content/pdf/10.1007/s00204-020-02924-x.pdf PDF Version] | |||
*Citation: Rodrigo, G., Jaccard, G., Tafin Djoko, D. et al. Cancer potencies and margin of exposure used for comparative risk assessment of heated tobacco products and electronic cigarettes aerosols with cigarette smoke. Arch Toxicol 95, 283–298 (2021). https://doi.org/10.1007/s00204-020-02924-x | |||
===2020: [https://www.manilatimes.net/2020/02/10/news/top-stories/expert-sounds-alarm-on-oral-cancer/681916 Expert sounds alarm on oral cancer]=== | ===2020: [https://www.manilatimes.net/2020/02/10/news/top-stories/expert-sounds-alarm-on-oral-cancer/681916 Expert sounds alarm on oral cancer]=== | ||
*A dental expert urged smokers to switch to electronic cigarettes (e-cigs) and heated tobacco products (HTPs) as a “harm reduction measure,” saying smoking is the leading cause of oral cancer. “We warn our patients who are smokers that smoking is the leading cause of oral cancer and strongly advise them to quit smoking. For those who cannot or do not want to quit smoking by themselves or with currently approved methods, we convince them to switch to non-combustible alternatives,” said Fernando Fernandez, president of the Philippine College of Oral and Maxillofacial Surgeons (Pcoms) during the Scientific Conversations on Tobacco Harm Reduction held recently at the Shangri-La at the Fort in Taguig City. | *A dental expert urged smokers to switch to electronic cigarettes (e-cigs) and heated tobacco products (HTPs) as a “harm reduction measure,” saying smoking is the leading cause of oral cancer. “We warn our patients who are smokers that smoking is the leading cause of oral cancer and strongly advise them to quit smoking. For those who cannot or do not want to quit smoking by themselves or with currently approved methods, we convince them to switch to non-combustible alternatives,” said Fernando Fernandez, president of the Philippine College of Oral and Maxillofacial Surgeons (Pcoms) during the Scientific Conversations on Tobacco Harm Reduction held recently at the Shangri-La at the Fort in Taguig City. | ||
*Citation: | *Citation: | ||
===2020: [https://www.sciencedirect.com/science/article/abs/pii/S0304389420314060 Comparison of the chemical composition of aerosols from heated tobacco products, electronic cigarettes and tobacco cigarettes and their toxic impacts on the human bronchial epithelial BEAS-2B cells]=== | |||
*We first report that HTP (Heated Tobacco Product) delivers slightly less nicotine and emits much lower amounts of carbonyl and PAH compounds than tobacco cigarettes. | |||
*However, HTP emissions still contain carcinogenic compounds (e.g. formaldehyde, acetaldehyde and benzo[a]pyrene) and the amounts of carbonyls and PAHs in HTP aerosols are higher than in e-cig vapours (vapor). | |||
*In accordance with the levels of toxic compounds in each aerosol, HTP aerosol exhibits reduced cytotoxicity compared to cigarette smoke but higher than e-cig vapours. | |||
*HTP and e-cig have the potential to increase oxidative stress and inflammatory response, in a manner very similar to that of cigarette smoke, but only after a more intensive exposure. In addition, our data support that e-cig use at higher power settings emit higher carbonyl and PAH compounds and, consequently, generate more oxidative stress. | |||
*Finally, this study contributes to a better understanding of HTP and e-cig emission properties and their related toxicological impacts and provides important data needed for risk assessment purposes, by demonstrating that HTP might be less harmful than tobacco cigarettes but considerably more harmful than e-cig. | |||
*[https://pdf.sciencedirectassets.com/271390/1-s2.0-S0304389420X00161/1-s2.0-S0304389420314060/am.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEDoaCXVzLWVhc3QtMSJGMEQCIC20cepD3xWxO%2BHPfyvs9%2Fj4JkBZED8%2FyZivSvEh3DKqAiBV6d6I8BClyK7mRN2vsTLG4tpeRZvzFFTRm6iTWpF4jyr6AwhzEAQaDDA1OTAwMzU0Njg2NSIMned%2B2ZjGntQWfryIKtcDCllJ3BD59q7X1IUBsGkzgt4LlI8%2FeSiu7t8e8B0EG%2B9HDHMW8J%2BB8HskjtV8Nt7aw1o2iLkrks2014KOvf8SZuX5VRpbqj3m%2Fskb7%2BUDG9%2ByimsdJHgenWh4UjB0Y8fFA6bJuOtlbLYAKfbZL45ytPv0ne9iwFcCunPJJyZctT%2BG%2FdWtC%2FKtYDePqALnmkA54fA7C8aCG1FfAbKOTLP%2Fj68Zn5oKiaTP1iCuepTIC9PEtIbW3jDOHZxdeekOwvsOjmNil3T0bjm6xsBXMtp%2F1qjve6r0R%2F7GboJDGi9kE24Lf%2FvMAyQke%2BeauRLigBTGlm6ZGBqoJLYuOCXS%2FOg7SDhxVmvGzteddKKt6rpu0Tdo4Y2zcfaBHWAUELShFRp8GHjEWgFW1WKMZlMxdbyuVS7D6zK7lY8Rl1QCS8UDTYPJ9KgYYZLyBzBAjoZoBHqDOfEd2Pq27F%2FYGm1DnUv%2ByHpVpnas1kInRwTQP8lCidzbXQ5amJYnVPdmK0e19y1N0qmneUxb7c4l8U%2BkJ%2FOvQBs5NeiFB16v3dt01MdJJgM5zytE%2FjVJlSDx6o46Cf86rPbsCjz679RrmXM4LZ9pqkLYrGu8OVkgwCfxPyD5lz4DRL1lC6pzMO%2FfookGOqYBW4NimJC3eAF1AV5d2eDsUfNKwuiOp6l7LfvJX79t0%2BfegtSoPQAw7I%2FuhraeUNkUnCPTJiJpjyvTFI3xqcdZ2U%2FX%2BoGXCUbuw6dW4ep4ENLAdCmbPDpGkSzAPPmsNYetpOykif9Stz9O1Q3jdKAQEU2sfmVcyi76UYFI28ZPRcxx39CYrSpCIf3Wl0aulvqVJwgwpPEudIFT045A6LSCwcpnedfscg%3D%3D&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20210827T101042Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTYXMGQQFJ3%2F20210827%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Signature=f6c7708f1578fd81e69a1e8d00ced8d31682c3b06a80829dc98b39b50a0b73e8&hash=e8aba33ee6d0e02c3f302c62a141e2e530d9bd77a9c95cc0c734640f9a0b5e8b&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S0304389420314060&tid=pdf-78980aac-f8f1-4bf1-8d13-dac5c6840db5&sid=f2637e30858078455208ee9417a65d1e0937gxrqa&type=client PDF Version] | |||
*Citation: Romain Dusautoir, Gianni Zarcone, Marie Verriele, Guillaume Garçon, Isabelle Fronval, Nicolas Beauval, Delphine Allorge, Véronique Riffault, Nadine Locoge, Jean-Marc Lo-Guidice, Sébastien Anthérieu, Comparison of the chemical composition of aerosols from heated tobacco products, electronic cigarettes and tobacco cigarettes and their toxic impacts on the human bronchial epithelial BEAS-2B cells, Journal of Hazardous Materials, Volume 401, 2021, 123417, ISSN 0304-3894, doi:10.1016/j.jhazmat.2020.123417 | |||
===2019: [https://pubmed.ncbi.nlm.nih.gov/30564805/ Effects of cigarette smoke and tobacco heating aerosol on color stability of dental enamel, dentin, and composite resin restorations]=== | ===2019: [https://pubmed.ncbi.nlm.nih.gov/30564805/ Effects of cigarette smoke and tobacco heating aerosol on color stability of dental enamel, dentin, and composite resin restorations]=== | ||
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