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===2019: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722047/ A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment]=== | ===2019: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722047/ A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment]=== | ||
*Overall, the study demonstrated that exposure to undiluted test mix or base EC aerosols under the testing conditions (an acute 28-min exposure), even at a deposited nicotine concentration that is 200 times greater than that found in the saliva of EC users, had no impact on morphology of buccal and small airway cultures. In contrast, following the same puff number, the already diluted 3R4F CS resulted in overt tissue damage. | *Overall, the study demonstrated that exposure to undiluted test mix or base EC aerosols under the testing conditions (an acute 28-min exposure), even at a deposited nicotine concentration that is 200 times greater than that found in the saliva of EC users, had no impact on morphology of buccal and small airway cultures. In contrast, following the same puff number, the already diluted 3R4F CS resulted in overt tissue damage. | ||
*Citation: | *Citation: Iskandar AR, Zanetti F, Kondylis A, Martin F, Leroy P, Majeed S, Steiner S, Xiang Y, Ortega Torres L, Trivedi K, Guedj E, Merg C, Frentzel S, Ivanov NV, Doshi U, Lee KM, McKinney WJ Jr, Peitsch MC, Hoeng J. A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment. Intern Emerg Med. 2019 Sep;14(6):863-883. doi: 10.1007/s11739-019-02055-x. Epub 2019 Mar 5. PMID: 30835057; PMCID: PMC6722047. | ||
===2019: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949915/ A Comparison of Flavorless Electronic Cigarette-Generated Aerosol and Conventional Cigarette Smoke on the Planktonic Growth of Common Oral Commensal Streptococci]=== | ===2019: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949915/ A Comparison of Flavorless Electronic Cigarette-Generated Aerosol and Conventional Cigarette Smoke on the Planktonic Growth of Common Oral Commensal Streptococci]=== | ||
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