Nicotine Flux: Difference between revisions
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*"A potential first step in effective regulation may involve regulating the rate at which nicotine is emitted from an e-cigarette (i.e., nicotine “flux”; [98,99]). Using nicotine flux as a regulatory target, all of the factors that influence it (e.g., device power, liquid nicotine concentration, user behavior) can be accounted for, and conditions that produce a flux that is too low (i.e., ineffective nicotine delivery) or too high (e.g., exceeding the flux of a combustible cigarette) can be made unavailable to consumers. Whether or not nicotine flux is the correct regulatory target, the current state of affairs, in which uninformed consumers use products that may or may not deliver nicotine and a variety of other toxicants, is incompatible with an empirically-based regulatory approach that prioritizes public health." | *"A potential first step in effective regulation may involve regulating the rate at which nicotine is emitted from an e-cigarette (i.e., nicotine “flux”; [98,99]). Using nicotine flux as a regulatory target, all of the factors that influence it (e.g., device power, liquid nicotine concentration, user behavior) can be accounted for, and conditions that produce a flux that is too low (i.e., ineffective nicotine delivery) or too high (e.g., exceeding the flux of a combustible cigarette) can be made unavailable to consumers. Whether or not nicotine flux is the correct regulatory target, the current state of affairs, in which uninformed consumers use products that may or may not deliver nicotine and a variety of other toxicants, is incompatible with an empirically-based regulatory approach that prioritizes public health." | ||
*Citation: Voos N, Goniewicz ML, Eissenberg T. What is the nicotine delivery profile of electronic cigarettes? Expert Opin Drug Deliv. 2019 Nov;16(11):1193-1203. doi: 10.1080/17425247.2019.1665647. Epub 2019 Sep 13. PMID: 31495244; PMCID: PMC6814574. | *Citation: Voos N, Goniewicz ML, Eissenberg T. What is the nicotine delivery profile of electronic cigarettes? Expert Opin Drug Deliv. 2019 Nov;16(11):1193-1203. doi: 10.1080/17425247.2019.1665647. Epub 2019 Sep 13. PMID: 31495244; PMCID: PMC6814574. | ||
==2019: [https://repositorio.udd.cl/server/api/core/bitstreams/59c237c0-2d39-4275-a093-180806468be8/content 3. Clinical pharmacology of nicotine in electronic nicotine delivery systems]== | |||
*To address the first concern, there is growing interest in measuring nicotine “flux”, the rate at which nicotine is emitted from ENDS (56, 57). Nicotine flux can be measured (usually reported in µg/s) and can be compared among ENDS and with cigarettes. Those ENDS that mimic the flux of a cigarette may be more likely to substitute well for a cigarette than ENDS that do not. | |||
*Armando Peruga, Centre of Epidemiology and Health Policies, School of Medicine, Clínica Alemana, University of Desarrollo, Chile and Thomas Eissenberg, Center for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, USA | |||
*Citation: WHO Study Group on [http://Tobacco%20Product%20Regulation Tobacco Product Regulation]. Report on the scientific basis of tobacco product regulation: seventh report of a WHO study group. Geneva: World Health Organization; 2019 (WHO Technical Report Series, No. 1015). Licence: CC BY-NC-SA 3.0 IGO. | |||
==2017: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502764/ Transport phenomena governing nicotine emissions from electronic cigarettes: model formulation and experimental investigation]== | ==2017: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502764/ Transport phenomena governing nicotine emissions from electronic cigarettes: model formulation and experimental investigation]== | ||