Nicotine therapeutic benefits: Difference between revisions
| Line 1,365: | Line 1,365: | ||
**Citation: Mehta JN, Martin AG. A case of pemphigus vulgaris improved by cigarette smoking. Arch Dermatol. 2000 Jan;136(1):15-7. doi: 10.1001/archderm.136.1.15. PMID: 10632179. | **Citation: Mehta JN, Martin AG. A case of pemphigus vulgaris improved by cigarette smoking. Arch Dermatol. 2000 Jan;136(1):15-7. doi: 10.1001/archderm.136.1.15. PMID: 10632179. | ||
<br> | <br> | ||
='''Pregnancy'''= | |||
==Preeclampsia== | |||
===2024: [https://www.sciencedirect.com/science/article/abs/pii/S0303720724003022 Nicotine increases hepatocyte transthyretin turnover: a possible mechanism for the protective effect of smoking on preeclampsia?]=== | |||
*Nicotine exposure increases hepatocyte synthesis, secretion and uptake of transthyretin as well as cell uptake of soluble endoglin. Nicotine may protect against preeclampsia by increasing serum TTR which can bind soluble endoglin and remove it from the circulation. Further research is required to better understand the role of transthyretin and nicotine in mitigating preeclampsia. | |||
**Citation: Young M, McLeod DSA, Richard K. Nicotine increases hepatocyte transthyretin turnover: A possible mechanism for the protective effect of smoking on preeclampsia? Mol Cell Endocrinol. 2025 Feb 1;597:112446. doi: 10.1016/j.mce.2024.112446. Epub 2024 Dec 24. PMID: 39725350. | |||
***Acknowledgement: This study was funded by the Science Education and Research Committee, Pathology Queensland. | |||
<br> | |||
='''Psoriasis'''= | ='''Psoriasis'''= | ||