| Line 241: | Line 241: | ||
**"Unless one assumes that unflavored coffee beans pose a serious risk of “popcorn lung,” a rare and oftentimes lethal disease, then one should agree that exposures to airborne diketone levels above the NIOSH and ACGIH OELs are not necessarily indicative of respiratory risk." | **"Unless one assumes that unflavored coffee beans pose a serious risk of “popcorn lung,” a rare and oftentimes lethal disease, then one should agree that exposures to airborne diketone levels above the NIOSH and ACGIH OELs are not necessarily indicative of respiratory risk." | ||
**"Similarly, we measured concentrations of naturally occurring diacetyl and 2,3-pentanedione in mainstream cigarette smoke at levels (200–400 ppm and 30–50 ppm, respectively) that are hundreds of thousands of times higher than the NIOSH and ACGIH OELs, yet cigarette smoking is not associated with “popcorn lung”. Also, as others have noted, diketone exposures from traditional cigarettes are higher than those associated with e-cigarette use, hence switching from tobacco to e-cigarettes may result in reduced diketone exposure." | **"Similarly, we measured concentrations of naturally occurring diacetyl and 2,3-pentanedione in mainstream cigarette smoke at levels (200–400 ppm and 30–50 ppm, respectively) that are hundreds of thousands of times higher than the NIOSH and ACGIH OELs, yet cigarette smoking is not associated with “popcorn lung”. Also, as others have noted, diketone exposures from traditional cigarettes are higher than those associated with e-cigarette use, hence switching from tobacco to e-cigarettes may result in reduced diketone exposure." | ||
**"Ironically, suggesting that diketone levels in e-cigarettes are potentially dangerous could actually lead to higher diketone exposures in the smoking population if smokers decide not to switch to e-cigarettes due to as yet unfounded health concerns." (Pierce, Abelmann, Finley) | **"Ironically, suggesting that diketone levels in e-cigarettes are potentially dangerous could actually lead to higher diketone exposures in the smoking population if smokers decide not to switch to e-cigarettes due to as yet unfounded health concerns." (Pierce, Abelmann, Finley) For further information, see authors [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892901/ response] to the comments above. | ||
*See Also: 2016: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892907/ On the Vapor Trail: Examining the Chemical Content of E-Cigarette Flavorings] | *See Also: 2016: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892907/ On the Vapor Trail: Examining the Chemical Content of E-Cigarette Flavorings] | ||
**"The 51 e-juices sampled make up a very small proportion of all the products sold, and there is variability in the chemical content of specific products as well as how those chemicals are delivered by different devices. The authors therefore acknowledge that it is impossible to extrapolate their results to all the other products on the market. Importantly, this study did not assess levels of diacetyl, 2,3-pentanedione, and acetoin in actual users, much less health effects. So it’s premature to assume that exposure to these chemicals via e-cigarettes causes health problems." (Arnold) | **"The 51 e-juices sampled make up a very small proportion of all the products sold, and there is variability in the chemical content of specific products as well as how those chemicals are delivered by different devices. The authors therefore acknowledge that it is impossible to extrapolate their results to all the other products on the market. Importantly, this study did not assess levels of diacetyl, 2,3-pentanedione, and acetoin in actual users, much less health effects. So it’s premature to assume that exposure to these chemicals via e-cigarettes causes health problems." (Arnold) | ||
*See Also: 2015: [https://rodutobaccotruth.blogspot.com/2015/12/is-harvard-e-cigarette-buttery-flavor.html Is the Harvard E-Cigarette Buttery Flavor Study Credible?] | *See Also: 2015: [https://rodutobaccotruth.blogspot.com/2015/12/is-harvard-e-cigarette-buttery-flavor.html Is the Harvard E-Cigarette Buttery Flavor Study Credible?] | ||
**"As I advised previously, vapers should only use liquids that are certified to be free of buttery flavors that are suspected respiratory toxicants. However, laboratory investigations of e-cigarettes should use validated methods to assure credibility. The results of the Harvard Buttery Flavor Study do not meet this standard." (Rodu) | **"As I advised previously, vapers should only use liquids that are certified to be free of buttery flavors that are suspected respiratory toxicants. However, laboratory investigations of e-cigarettes should use validated methods to assure credibility. The results of the Harvard Buttery Flavor Study do not meet this standard." (Rodu) | ||
edits