Nicotine - Retracted Studies, Papers, and Articles: Difference between revisions

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*"The problem with these studies is disentangling the effects of a smoking career (something more complicated than adjusting for current-, former-, never-smoking status) and subsequent vaping behaviour. Also, the relationships are complicated by reverse causation (was the vaping a response to smoking-induced respiratory symptoms?), a hard-to-define counterfactual (has the vaping displaced smoking or displaced abstinence?), and the fact that respiratory damage arises from cumulative exposure and vaping exposures may be adding incremental risk (would the subject have any symptoms if they hadn't smoked first?)." (Bates)
*"The problem with these studies is disentangling the effects of a smoking career (something more complicated than adjusting for current-, former-, never-smoking status) and subsequent vaping behaviour. Also, the relationships are complicated by reverse causation (was the vaping a response to smoking-induced respiratory symptoms?), a hard-to-define counterfactual (has the vaping displaced smoking or displaced abstinence?), and the fact that respiratory damage arises from cumulative exposure and vaping exposures may be adding incremental risk (would the subject have any symptoms if they hadn't smoked first?)." (Bates)
*Referring to: Varella MH, Andrade OA, Shaffer SM, Castro G, Rodriguez P, Barengo NC, Acuna JM. E-cigarette use and respiratory symptoms in residents of the United States: A BRFSS report. PLoS One. 2022 Dec 1;17(12):e0269760. doi: 10.1371/journal.pone.0269760. PMID: 36454742; PMCID: PMC9714717.
*Referring to: Varella MH, Andrade OA, Shaffer SM, Castro G, Rodriguez P, Barengo NC, Acuna JM. E-cigarette use and respiratory symptoms in residents of the United States: A BRFSS report. PLoS One. 2022 Dec 1;17(12):e0269760. doi: 10.1371/journal.pone.0269760. PMID: 36454742; PMCID: PMC9714717.
===2020: [https://pubpeer.com/publications/CEB008BBD48F89272321EB50092793 Association Between Youth Smoking, Electronic Cigarette Use, and COVID-19]===
*Multiple Comments:
**"This article is getting severe criticism on Twitter. This thread summarises one issue and links to threads on other, more classic, problems." (Brown) Further comments by the same author (Brown) point out some errors in tables.
**"The authors surveyed and controlled for socioeconomic factors, ethnicity and compliance with confinement precautions, but not for other risk behaviors besides smoking or vaping (such as alcohol drinking, substance usage, unprotected sex). The lack of this important comparative context further weakens the conclusions of this study." (Sussman)
**"Flaws in the paper itself are only one part of the problem that needs to be addressed by the authors. The other is the public relations offensive mounted on the back of the paper once it was published in the Journal of Adolescent Health on August 11." "Unsurprisingly, such an incendiary claim generated considerable media coverage, even though there is no basis for it in fact or evidence." "Finally, there was a political dimension. On the same day as the article was published, August 11, 2020, Illinois Congressman Raja Krishnamoorthi, Chairman of the Subcommittee on Economic and Consumer Policy, found time to write a press release and letter to the Commissioner of the Food and Drug Administration, Dr. Stephen Hahn demanding FDA "clear the market of e-cigarettes" in response to the study." (Bates)
*See Also:[https://www.qeios.com/read/A58MQC Qeios 1]
**"In this brief peer review, we argue that the data reported by Gaiha et al (https://doi.org/10.1016/j.jadohealth.2020.07.002) regarding associations between vaping and COVID-19 testing are so suspect that any conclusions drawn from it cannot be relied upon. We discuss six main areas of concern and conclude that the paper should be retracted." (Gitchell, Kleykamp, Niaura, Shiffman, Cummings, Sweanor, Abrams)
*[https://www.qeios.com/read/TCEJ7G Qeios 2]
**"In a recent study, Gaiha et al. examined the association between e-cigarette use and COVID-19 in an online cross-sectional study of people aged 13-24 years conducted from May 6 to May 14, 2020. We have noticed serious issues in population weighting, response bias and biological implausibility. The suggested conclusions and interpretation of the study findings cannot be considered reliable. These issues raise the question of retracting the study." (Farsalinos, Niaura)
*Referring to: Gaiha SM, Cheng J, Halpern-Felsher B. Association Between Youth Smoking, Electronic Cigarette Use, and COVID-19. J Adolesc Health. 2020 Oct;67(4):519-523. doi: 10.1016/j.jadohealth.2020.07.002. Epub 2020 Aug 11. PMID: 32798097; PMCID: PMC7417895.


===2019-2020: [https://pubpeer.com/publications/7571819CEB7A2BC425BE3D7061410D Association of E-Cigarette Use With Respiratory Disease Among Adults: A Longitudinal Analysis]===
===2019-2020: [https://pubpeer.com/publications/7571819CEB7A2BC425BE3D7061410D Association of E-Cigarette Use With Respiratory Disease Among Adults: A Longitudinal Analysis]===