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*"A potential first step in effective regulation may involve regulating the rate at which nicotine is emitted from an e-cigarette (i.e., nicotine “flux”; [98,99]). Using nicotine flux as a regulatory target, all of the factors that influence it (e.g., device power, liquid nicotine concentration, user behavior) can be accounted for, and conditions that produce a flux that is too low (i.e., ineffective nicotine delivery) or too high (e.g., exceeding the flux of a combustible cigarette) can be made unavailable to consumers. Whether or not nicotine flux is the correct regulatory target, the current state of affairs, in which uninformed consumers use products that may or may not deliver nicotine and a variety of other toxicants, is incompatible with an empirically-based regulatory approach that prioritizes public health." | *"A potential first step in effective regulation may involve regulating the rate at which nicotine is emitted from an e-cigarette (i.e., nicotine “flux”; [98,99]). Using nicotine flux as a regulatory target, all of the factors that influence it (e.g., device power, liquid nicotine concentration, user behavior) can be accounted for, and conditions that produce a flux that is too low (i.e., ineffective nicotine delivery) or too high (e.g., exceeding the flux of a combustible cigarette) can be made unavailable to consumers. Whether or not nicotine flux is the correct regulatory target, the current state of affairs, in which uninformed consumers use products that may or may not deliver nicotine and a variety of other toxicants, is incompatible with an empirically-based regulatory approach that prioritizes public health." | ||
*Citation: Voos N, Goniewicz ML, Eissenberg T. What is the nicotine delivery profile of electronic cigarettes? Expert Opin Drug Deliv. 2019 Nov;16(11):1193-1203. doi: 10.1080/17425247.2019.1665647. Epub 2019 Sep 13. PMID: 31495244; PMCID: PMC6814574. | *Citation: Voos N, Goniewicz ML, Eissenberg T. What is the nicotine delivery profile of electronic cigarettes? Expert Opin Drug Deliv. 2019 Nov;16(11):1193-1203. doi: 10.1080/17425247.2019.1665647. Epub 2019 Sep 13. PMID: 31495244; PMCID: PMC6814574. | ||
==2017: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502764/ Transport phenomena governing nicotine emissions from electronic cigarettes: model formulation and experimental investigation]== | |||
*"Performance standards are commonly written in consumer product regulations in the USA and elsewhere, and with the appropriate scientific basis, can be developed for ECIGs. To the extent that proposed performance standards will involve nicotine emissions, models like the one described can be used to predict nicotine emissions of any existing or future ECIG product, without recourse to costly testing in an analytical laboratory. These models can also be used to test the effects of proposed regulation on factors that influence nicotine flux." | |||
*Citation: Talih S, Balhas Z, Salman R, El-Hage R, Karaoghlanian N, El-Hellani A, Baassiri M, Jaroudi E, Eissenberg T, Saliba N, Shihadeh A. Transport phenomena governing nicotine emissions from electronic cigarettes: model formulation and experimental investigation. Aerosol Sci Technol. 2017;51(1):1-11. doi: 10.1080/02786826.2016.1257853. Epub 2016 Nov 8. PMID: 28706340; PMCID: PMC5502764. | |||
==2015: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837999/ Electronic Cigarette Effectiveness and Abuse Liability: Predicting and Regulating Nicotine Flux]== | ==2015: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837999/ Electronic Cigarette Effectiveness and Abuse Liability: Predicting and Regulating Nicotine Flux]== | ||
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