Nicotine therapeutic benefits: Difference between revisions

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**Citation: Maruta K, Watanabe C, Hozumi H, Kurihara C, Furuhashi H, Takajo T, Okada Y, Shirakabe K, Higashiyama M, Komoto S, Tomita K, Nagao S, Ishizuka T, Miura S, Hokari R. Nicotine treatment ameliorates DSS-induced colitis by suppressing MAdCAM-1 expression and leukocyte recruitment. J Leukoc Biol. 2018 Nov;104(5):1013-1022. doi: 10.1002/JLB.3A0717-304R. Epub 2018 Jun 14. PMID: 29901817.

***Acknowledgement: This research was supported by grants from the National Defense Medical College, by Grants-in-aid for the Intractable Diseases Project of the Ministry of Health, Labour, and Welfare of Japan, and by Grantsin-aid for Scientific Research from the Japanese Ministry of Education (2646080).

===2013 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533410/ Novel Insights on the Effect of Nicotine in a Murine Colitis Model]===

*Animal study

*Administration of low, but not high, doses of oral nicotine in DSS-treated mice resulted in a significant decrease in disease severity, histologic damage scores, as well as colonic level of tumor necrosis factor-α.

**Citation: AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. J Pharmacol Exp Ther. 2013 Jan;344(1):207-17. doi: 10.1124/jpet.112.198796. Epub 2012 Oct 31. PMID: 23115221; PMCID: PMC3533410.

***Acknowledgement: This work was supported by National Institutes of Health [Grants DA-019377; (to M.I.D.) and DK 046367] (to H.I.A.).

===2011 [https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-129 Anti-inflammatory effects of nicotine in obesity and ulcerative colitis]===

@@ Line 499: / Line 499: @@
 **Citation: Maruta K, Watanabe C, Hozumi H, Kurihara C, Furuhashi H, Takajo T, Okada Y, Shirakabe K, Higashiyama M, Komoto S, Tomita K, Nagao S, Ishizuka T, Miura S, Hokari R. Nicotine treatment ameliorates DSS-induced colitis by suppressing MAdCAM-1 expression and leukocyte recruitment. J Leukoc Biol. 2018 Nov;104(5):1013-1022. doi: 10.1002/JLB.3A0717-304R. Epub 2018 Jun 14. PMID: 29901817.
 ***Acknowledgement: This research was supported by grants from the National Defense Medical College, by Grants-in-aid for the Intractable Diseases Project of the Ministry of Health, Labour, and Welfare of Japan, and by Grantsin-aid for Scientific Research from the Japanese Ministry of Education (2646080).
+===2013 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533410/ Novel Insights on the Effect of Nicotine in a Murine Colitis Model]===
+*Animal study
+*Administration of low, but not high, doses of oral nicotine in DSS-treated mice resulted in a significant decrease in disease severity, histologic damage scores, as well as colonic level of tumor necrosis factor-α.
+**Citation: AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. J Pharmacol Exp Ther. 2013 Jan;344(1):207-17. doi: 10.1124/jpet.112.198796. Epub 2012 Oct 31. PMID: 23115221; PMCID: PMC3533410.
+***Acknowledgement: This work was supported by National Institutes of Health [Grants DA-019377; (to M.I.D.) and DK 046367] (to H.I.A.).
 ===2011 [https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-129 Anti-inflammatory effects of nicotine in obesity and ulcerative colitis]===