Nicotine therapeutic benefits: Difference between revisions
Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice |
Regulatory effect of nicotine on collagen-induced arthritis and on the induction and function of in vitro-cultured Th17 cells |
||
| Line 226: | Line 226: | ||
='''Arthritis/Skeletal'''= | ='''Arthritis/Skeletal'''= | ||
===2014 [https://pubmed.ncbi.nlm.nih.gov/24313917/ Regulatory effect of nicotine on collagen-induced arthritis and on the induction and function of in vitro-cultured Th17 cells]=== | |||
*Animal Study | |||
*Nicotine stimulation attenuated signs and severity of arthritis in mice. Activation of nicotine acetylcholine receptors on in vitro-cultured Th17 cells decreased their pro-inflammatory function, which may play a potential role in alleviating arthritis in mice. | |||
*[https://sci-hub.st/10.3109/14397595.2013.862352 PDF Full paper] | |||
**Citation: Yang Y, Yang Y, Yang J, Xie R, Ren Y, Fan H. Regulatory effect of nicotine on collagen-induced arthritis and on the induction and function of in vitro-cultured Th17 cells. Mod Rheumatol. 2014 Sep;24(5):781-7. doi: 10.3109/14397595.2013.862352. Epub 2013 Dec 9. PMID: 24313917. | |||
***Acknowledgement: This work was supported by The Shanghai Committee of Science and Technology Project, China (Grant No. 12GWZX0201,11140902900). | |||
===2009 [https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.24177 Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice]=== | ===2009 [https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.24177 Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice]=== | ||