Nicotine therapeutic benefits: Difference between revisions
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='''Sepsis/Septic'''= | ='''Sepsis/Septic/endotoxemia/infection'''= | ||
===2024 [https://www.sciencedirect.com/science/article/pii/S0014488624002723 Acute nicotine exposure attenuates neurological deficits, ischemic injury and brain inflammatory responses and restores hippocampal long-term potentiation in ischemic stroke followed by lipopolysaccharide-induced sepsis-like state]=== | ===2024 [https://www.sciencedirect.com/science/article/pii/S0014488624002723 Acute nicotine exposure attenuates neurological deficits, ischemic injury and brain inflammatory responses and restores hippocampal long-term potentiation in ischemic stroke followed by lipopolysaccharide-induced sepsis-like state]=== | ||
*Animal Study | *Animal Study | ||
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**Citation: Kim TH, Kim SJ, Lee SM. Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation. J Infect Dis. 2014 May 15;209(10):1668-77. doi: 10.1093/infdis/jit669. Epub 2013 Dec 1. Erratum in: J Infect Dis. 2015 Mar 1;211(5):851. doi: 10.1093/infdis/jiu824. PMID: 24298024. | **Citation: Kim TH, Kim SJ, Lee SM. Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation. J Infect Dis. 2014 May 15;209(10):1668-77. doi: 10.1093/infdis/jit669. Epub 2013 Dec 1. Erratum in: J Infect Dis. 2015 Mar 1;211(5):851. doi: 10.1093/infdis/jiu824. PMID: 24298024. | ||
***Acknowledgement: This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, Information and Communication Technologies (ICT) and Future Planning (NRF-2013R1A1A3008145). | ***Acknowledgement: This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, Information and Communication Technologies (ICT) and Future Planning (NRF-2013R1A1A3008145). | ||
===2011 [https://pubmed.ncbi.nlm.nih.gov/20805763/ Carbachol alleviates rat cytokine release and organ dysfunction induced by lipopolysaccharide]=== | |||
*Animal Study | |||
*The results suggested that both carbachol and nicotine play a role in the anti-inflammatory process and organ function protection through the α7 subunit of nicotinic cholinergic receptor. | |||
*[https://sci-hub.st/10.1097/TA.0b013e3181e9732d PDF Full Paper] | |||
**Citation: Zhou G, Hu S, Lv Y, Song Q, Zou X, Sheng Z. Carbachol alleviates rat cytokine release and organ dysfunction induced by lipopolysaccharide. J Trauma. 2011 Jul;71(1):157-62. doi: 10.1097/TA.0b013e3181e9732d. PMID: 20805763. | |||
***Acknowledgement: From the Laboratory of Shock and Organ Dysfunction (G.Z., S.H., Y.L., Q.S., X.Z., Z.S.), Burn Institute, the First Hospital Affiliated to the People’s Liberation Army General Hospital, Beijing, China. | |||
===2005 [https://academic.oup.com/jid/article/191/12/2138/842542 The Cholinergic Anti-Inflammatory Pathway Regulates the Host Response during Septic Peritonitis]=== | ===2005 [https://academic.oup.com/jid/article/191/12/2138/842542 The Cholinergic Anti-Inflammatory Pathway Regulates the Host Response during Septic Peritonitis]=== | ||