(adding content) |
(adding content) |
||
| Line 20: | Line 20: | ||
*Citation: Ikonomidis, I., Katogiannis, K., Kostelli, G., Kourea, K., Kyriakou, E., Kypraiou, A., Tsoumani, M., Andreadou, I., Lambadiari, V., Plotas, P., Thymis, I., & Tsantes, A. E. (2020). Effects of electronic cigarette on platelet and vascular function after four months of use. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 141, 111389. https://doi.org/10.1016/j.fct.2020.111389 | *Citation: Ikonomidis, I., Katogiannis, K., Kostelli, G., Kourea, K., Kyriakou, E., Kypraiou, A., Tsoumani, M., Andreadou, I., Lambadiari, V., Plotas, P., Thymis, I., & Tsantes, A. E. (2020). Effects of electronic cigarette on platelet and vascular function after four months of use. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 141, 111389. https://doi.org/10.1016/j.fct.2020.111389 | ||
===2020: Differential Effects of Tobacco Cigarettes and Electronic Cigarettes on Endothelial Function in Healthy Young People=== | ===2020: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509270/ Differential Effects of Tobacco Cigarettes and Electronic Cigarettes on Endothelial Function in Healthy Young People]=== | ||
*Endothelial dysfunction, as measured by flow mediated vasodilation(FMD) is a predictor of future atherosclerosis and adverse cardiovascular events, and is impaired in tobacco cigarette (TC) smokers. | |||
*Impaired FMD in TC smokers is most likely attributable to non-nicotine toxicants in TC smoke, since an equivalent increase in plasma nicotine from the EC did not lead to acute impairment in FMD. | |||
Endothelial dysfunction, as measured by flow mediated vasodilation(FMD) is a predictor of future atherosclerosis and adverse cardiovascular events, and is impaired in tobacco cigarette (TC) smokers. | *FMD was significantly impaired after smoking one TC, but not after vaping an equivalent "dose"(estimated plasma nicotine) of an e-cigarette (EC), consistent with the notion that non-nicotine constituents in TC smoke mediate the impairment. | ||
FMD was significantly impaired after smoking one TC, but not after vaping an equivalent "dose"(estimated plasma nicotine) of an e-cigarette (EC), consistent with the notion that non-nicotine constituents in TC smoke mediate the impairment. | *However, there is increasing scientific literature that supports the notion that ECs, although not harmless, may be less harmful than TC smoking for cardiovascular risk. | ||
*Acknowledgement: This work was supported by Tobacco-Related Disease Research Program Grants TRDRP 23XT-0006H (to H.R.M.), 25IR-0024H (to H.R.M.), and TRDRP 28IR-0065 (H.R.M.) and by National Institutes of Health, National Center for Advancing Translational Science UCLA CTSI Grant UL1TR001881. | |||
*Citation: Haptonstall KP, Choroomi Y, Moheimani R, Nguyen K, Tran E, Lakhani K, Ruedisueli I, Gornbein J, Middlekauff HR. Differential effects of tobacco cigarettes and electronic cigarettes on endothelial function in healthy young people. Am J Physiol Heart Circ Physiol. 2020 Sep 1;319(3):H547-H556. doi: 10.1152/ajpheart.00307.2020. Epub 2020 Jul 31. PMID: 32734819; PMCID: PMC7509270. | |||
===2019: Global Forum on Nicotine (GFN) The effect of electronic nicotine delivery systems (ends) and new tobacco products on the risk of cardiovascular disease in people with high tobacco dependence=== <!--T:7--> | ===2019: Global Forum on Nicotine (GFN) The effect of electronic nicotine delivery systems (ends) and new tobacco products on the risk of cardiovascular disease in people with high tobacco dependence=== <!--T:7--> | ||
edits