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===2018: [https://www.dovepress.com/health-effects-in-copd-smokers-who-switch-to-electronic-cigarettes-a-r-peer-reviewed-fulltext-article-COPD Health effects in COPD smokers who switch to electronic cigarettes: a retrospective-prospective 3-year follow-up]=== | ===2018: [https://www.dovepress.com/health-effects-in-copd-smokers-who-switch-to-electronic-cigarettes-a-r-peer-reviewed-fulltext-article-COPD Health effects in COPD smokers who switch to electronic cigarettes: a retrospective-prospective 3-year follow-up]=== | ||
*The present study suggests that EC use may ameliorate objective and subjective COPD outcomes and that the benefits gained may persist long-term. EC use may reverse some of the harm resulting from tobacco smoking in COPD patients | *The present study suggests that EC use may ameliorate objective and subjective COPD outcomes and that the benefits gained may persist long-term. EC use may reverse some of the harm resulting from tobacco smoking in COPD patients. | ||
===2018: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799303/ In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke]=== | |||
*The relationship between the identified RNA features and gene ontologies were mapped showing a strong association with stress response, xenobiotics metabolism, and COPD-related terms for 3R4F [combustible cigarette]. In contrast, fewer ontologies were found enriched for the THPs [heated tobacco product] aerosols. “Response to wounding” was a common COPD-related term over-represented for the two THPs but at a reduced significance. Quantification of a cytokine panel post-exposure confirmed a pro-inflammatory effect of cigarette smoke but not for THPs. In conclusion, THPs have a reduced impact on gene expression compared to 3R4F. | |||
===2017: [https://www.dovepress.com/e-cigarettes-in-patients-with-copd-current-perspectives-peer-reviewed-fulltext-article-COPD E-cigarettes in patients with COPD: current perspectives]=== | ===2017: [https://www.dovepress.com/e-cigarettes-in-patients-with-copd-current-perspectives-peer-reviewed-fulltext-article-COPD E-cigarettes in patients with COPD: current perspectives]=== | ||
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