Myth: Alternative nicotine products don't help people stop smoking: Difference between revisions

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*Validated smoking reduction (including cessation) was achieved by 26.5% vs 6.0% of participants in the EC and NRT study arms, respectively. Sustained validated abstinence rates at 6 months were 19.1% vs 3.0%.
*Validated smoking reduction (including cessation) was achieved by 26.5% vs 6.0% of participants in the EC and NRT study arms, respectively. Sustained validated abstinence rates at 6 months were 19.1% vs 3.0%.
*[https://onlinelibrary.wiley.com/doi/epdf/10.1111/add.15628 PDF Version]
*[https://onlinelibrary.wiley.com/doi/epdf/10.1111/add.15628 PDF Version]
*Citation: Myers Smith, K., Phillips-Waller, A., Pesola, F., McRobbie, H., Przulj, D., Orzol, M., and Hajek, P. (2021) E-cigarettes versus nicotine replacement treatment as harm reduction interventions for smokers who find quitting difficult: Randomised controlled trial. Addiction, doi.org/10.1111/add.15628
*Acknowledgements: The study was funded by a Tobacco Advisory Group project grant, Cancer Research UK (C6815/A20503).


===2021: [https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-021-00475-7 Electronic cigarettes in standard smoking cessation treatment by tobacco counselors in Flanders: E-cigarette users show similar if not higher quit rates as those using commonly recommended smoking cessation aids]===
===2021: [https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-021-00475-7 Electronic cigarettes in standard smoking cessation treatment by tobacco counselors in Flanders: E-cigarette users show similar if not higher quit rates as those using commonly recommended smoking cessation aids]===
*One third of the total sample was biochemically verified smoking abstinent 7 months after quit date, with e-cigarette users (40%) having significantly higher chances to be smoking abstinent than NRT users (23%).
*One third of the total sample was biochemically verified smoking abstinent 7 months after quit date, with e-cigarette users (40%) having significantly higher chances to be smoking abstinent than NRT users (23%).
*[https://harmreductionjournal.biomedcentral.com/track/pdf/10.1186/s12954-021-00475-7.pdf PDF Version]
*[https://harmreductionjournal.biomedcentral.com/track/pdf/10.1186/s12954-021-00475-7.pdf PDF Version]
*Citation: Adriaens, K., Belmans, E., Van Gucht, D. et al. Electronic cigarettes in standard smoking cessation treatment by tobacco counselors in Flanders: E-cigarette users show similar if not higher quit rates as those using commonly recommended smoking cessation aids. Harm Reduct J 18, 28 (2021). https://doi.org/10.1186/s12954-021-00475-7
*Acknowledgement: This research received no external funding. EB is supported by a PhD-fellowship of the Research Foundation – Flanders (FWO-Vlaanderen; 1177820N).


===2021: [https://pubmed.ncbi.nlm.nih.gov/33798919/ A systematic review of randomized controlled trials and network meta-analysis of e-cigarettes for smoking cessation]===
===2021: [https://pubmed.ncbi.nlm.nih.gov/33798919/ A systematic review of randomized controlled trials and network meta-analysis of e-cigarettes for smoking cessation]===
*Smokers assigned to use nicotine e-cigarettes were more likely to remain abstinent from smoking than those assigned to use licensed NRT, and both were more effective than usual care or placebo conditions.
*Smokers assigned to use nicotine e-cigarettes were more likely to remain abstinent from smoking than those assigned to use licensed NRT, and both were more effective than usual care or placebo conditions.
*Citation: Chan GCK, Stjepanović D, Lim C, Sun T, Shanmuga Anandan A, Connor JP, Gartner C, Hall WD, Leung J. A systematic review of randomized controlled trials and network meta-analysis of e-cigarettes for smoking cessation. Addict Behav. 2021 Aug;119:106912. doi: 10.1016/j.addbeh.2021.106912. Epub 2021 Mar 15. PMID: 33798919.


===2020: [https://pubmed.ncbi.nlm.nih.gov/32770246/ QuitNic: A pilot randomised controlled trial comparing nicotine vaping products with nicotine replacement therapy for smoking cessation following residential detoxification]===
===2020: [https://pubmed.ncbi.nlm.nih.gov/32770246/ QuitNic: A pilot randomised controlled trial comparing nicotine vaping products with nicotine replacement therapy for smoking cessation following residential detoxification]===
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*Retention was 63% at 6-weeks and 50% at 12-weeks. At 12-weeks, 68% of the NRT group reported using combination NRT while 96% of the NVP group used the device. Acceptability ratings for the products were high in both groups. At 12-weeks, 14% of the NVP group and 18% of the NRT group reported not smoking at all in the last 7 days. Mean CPD (Cigarettes Per Day) among continued smokers decreased significantly between baseline to 12-weeks in both groups; from 19.91 to 4.72 for the NVP group (p<0.001) and from 20.88 to 5.52 in the NRT group (p<0.001). Cravings and withdrawal symptoms significantly decreased for both groups.  
*Retention was 63% at 6-weeks and 50% at 12-weeks. At 12-weeks, 68% of the NRT group reported using combination NRT while 96% of the NVP group used the device. Acceptability ratings for the products were high in both groups. At 12-weeks, 14% of the NVP group and 18% of the NRT group reported not smoking at all in the last 7 days. Mean CPD (Cigarettes Per Day) among continued smokers decreased significantly between baseline to 12-weeks in both groups; from 19.91 to 4.72 for the NVP group (p<0.001) and from 20.88 to 5.52 in the NRT group (p<0.001). Cravings and withdrawal symptoms significantly decreased for both groups.  
*[https://sci-hub.se/10.1093/ntr/ntaa143 PDF Version]
*[https://sci-hub.se/10.1093/ntr/ntaa143 PDF Version]
*Citation: Bonevski, B., Manning, V., Wynne, O., Gartner, C., Borland, R., Baker, A. L., … Lubman, D. I. (2020). QuitNic: A pilot randomised controlled trial comparing nicotine vaping products with nicotine replacement therapy for smoking cessation following residential detoxification. Nicotine & Tobacco Research. doi:10.1093/ntr/ntaa143
*Acknowledgement: This study was supported by a VicHealth Innovation Research Grant (2016-0096).


===2020: [https://academic.oup.com/ntr/article/23/4/625/5906696?login=true Effectiveness of Electronic Cigarettes in Smoking Cessation: a Systematic Review and Meta-Analysis]===
===2020: [https://academic.oup.com/ntr/article/23/4/625/5906696?login=true Effectiveness of Electronic Cigarettes in Smoking Cessation: a Systematic Review and Meta-Analysis]===
*Our results suggest that nicotine-ECs may be more effective in smoking cessation when compared to placebo ECs or NRT.
*Our results suggest that nicotine-ECs may be more effective in smoking cessation when compared to placebo ECs or NRT.
*[https://sci-hub.st/10.1093/ntr/ntaa181 PDF Version]
*[https://sci-hub.st/10.1093/ntr/ntaa181 PDF Version]
*Citation: Igor Grabovac, MD, DSc, Moritz Oberndorfer, MSc, Jismy Fischer, Winfried Wiesinger, Sandra Haider, PhD, Thomas Ernst Dorner, MD, MPH, Effectiveness of Electronic Cigarettes in Smoking Cessation: A Systematic Review and Meta-analysis, Nicotine & Tobacco Research, Volume 23, Issue 4, April 2021, Pages 625–634, doi: 10.1093/ntr/ntaa181
*Acknowledgement: This study was funded by the Health Insurance Group of Styria (Steiermärkische Gebietskrankenkasse).


===2019: [https://www.journalslibrary.nihr.ac.uk/hta/hta23430#/abstract E-cigarettes compared with nicotine replacement therapy within the UK Stop Smoking Services: the TEC RCT]===
===2019: [https://www.journalslibrary.nihr.ac.uk/hta/hta23430#/abstract E-cigarettes compared with nicotine replacement therapy within the UK Stop Smoking Services: the TEC RCT]===
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*A detailed economic analysis confirmed that, because e-cigarettes incur lower NHS costs than NRT and generate a higher quit rate, e-cigarette use is more cost-effective.
*A detailed economic analysis confirmed that, because e-cigarettes incur lower NHS costs than NRT and generate a higher quit rate, e-cigarette use is more cost-effective.
*[https://njl-admin.nihr.ac.uk/document/download/2030301 PDF Version]
*[https://njl-admin.nihr.ac.uk/document/download/2030301 PDF Version]
*Citation: Hajek P, Phillips-Waller A, Przulj D, Pesola F, Myers Smith K, Bisal N, et al. E-cigarettes compared with nicotine replacement therapy within the UK Stop Smoking Services: the TEC RCT. Health Technol Assess 2019;23(43)
*Acknowledgement: This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, NETSCC, the HTA programme or the Department of Health and Social Care.
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