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=How Mistakes Can Happen= | =How Mistakes Can Happen= | ||
===Blog: [https://rodutobaccotruth.blogspot.com/2024/04/are-vape-aerosols-really-toxic.html Are Vape Aerosols Really Toxic?]=== | |||
*Addresses several studies | |||
===2022: [https://reason.com/wp-content/uploads/2022/12/Rodu-Plurphanswat-CrossSec-Studies-IAEM-2022.pdf Cross‑sectional e‑cigarette studies are unreliable without timing of exposure and disease diagnosis]=== | ===2022: [https://reason.com/wp-content/uploads/2022/12/Rodu-Plurphanswat-CrossSec-Studies-IAEM-2022.pdf Cross‑sectional e‑cigarette studies are unreliable without timing of exposure and disease diagnosis]=== | ||
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==HPHC - Harmful and Potentially Harmful Constituents== | ==HPHC - Harmful and Potentially Harmful Constituents== | ||
===2024: Comments RE: [https://www.sciencemediacentre.org/expert-reaction-to-observational-study-of-lead-and-uranium-levels-in-urine-of-teen-vapers/ Biomarkers of metal exposure in adolescent e-cigarette users: correlations with vaping frequency and flavouring]=== | |||
*"More important, to me as a statistician at least, is that this research can’t establish that the higher levels of lead and uranium in the urine of participants who said they vaped more often were actually caused by their vaping." (McConway) | |||
*"No control group (i.e., adolescents without any e-cigarette use) was included in the analysis...This study therefore cannot tell us anything about absolute increase in exposure to heavy metals from e-cigarette use in this population, only about relative exposure among less and more frequent e-cigarette users." (Shahab) | |||
*Referring to: Kochvar A, Hao G, Dai HD Biomarkers of metal exposure in adolescent e-cigarette users: correlations with vaping frequency and flavouring Tobacco Control Published Online First: 29 April 2024. doi: 10.1136/tc-2023-058554 | |||
===2023: Comments RE: [https://pubpeer.com/publications/F7311DC3982D9CD03C060190C9CFCB Arsenic and arsenic species in MOD, POD, and disposable POD electronic cigarette aerosols: a pilot study]=== | ===2023: Comments RE: [https://pubpeer.com/publications/F7311DC3982D9CD03C060190C9CFCB Arsenic and arsenic species in MOD, POD, and disposable POD electronic cigarette aerosols: a pilot study]=== | ||
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===2024: Comments RE: [https://www.ecigarette-research.org/research/index.php/research/2024/281-ecig-disease Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes]=== | ===2024: Comments RE: [https://www.ecigarette-research.org/research/index.php/research/2024/281-ecig-disease Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes]=== | ||
*"The study provides zero evidence on any risk associated with e-cigarette use, whether absolute risk or in comparison with smoking. The question that was supposed to be addressed in this metanalysis CANNOT be examined with the studies included in their analysis." (Farsalinos) | *"The study provides zero evidence on any risk associated with e-cigarette use, whether absolute risk or in comparison with smoking. The question that was supposed to be addressed in this metanalysis CANNOT be examined with the studies included in their analysis." (Farsalinos) | ||
*Referring to: Glantz SA, Nguyen N, Oliveira da Silva AL. Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes. NEJM Evid. 2024 Mar;3(3):EVIDoa2300229. [https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300229 doi: 10.1056/EVIDoa2300229] | *Referring to: Glantz SA, Nguyen N, Oliveira da Silva AL. Population-Based Disease Odds for E-Cigarettes and Dual Use versus Cigarettes. NEJM Evid. 2024 Mar;3(3):EVIDoa2300229. Epub 2024 Feb 27. PMID: 38411454. [https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300229 doi: 10.1056/EVIDoa2300229] | ||
===2022: Comments RE: [https://colinmendelsohn.com.au/wp-content/uploads/2022/07/Mendelsohn-Wodak-Hall-Borland.-A-critical-analysis-of-Ecigs-and-health-outcomes-systematic-review-of-global-evidence.-DAR-2022.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]=== | ===2022: Comments RE: [https://colinmendelsohn.com.au/wp-content/uploads/2022/07/Mendelsohn-Wodak-Hall-Borland.-A-critical-analysis-of-Ecigs-and-health-outcomes-systematic-review-of-global-evidence.-DAR-2022.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]=== | ||
*Contrary to the conclusions of the Banks review, the evidence suggests that vaping nicotine is an effective smoking cessation aid; that vaping is substantially less harmful than smoking tobacco; that vaping is diverting young people away from smoking; and that vaping by smokers is likely to have a major net public health benefit if widely available to adult Australian smokers. (Mendelsohn) | *Contrary to the conclusions of the Banks review, the evidence suggests that vaping nicotine is an effective smoking cessation aid; that vaping is substantially less harmful than smoking tobacco; that vaping is diverting young people away from smoking; and that vaping by smokers is likely to have a major net public health benefit if widely available to adult Australian smokers. (Mendelsohn) | ||
*Referring to: Banks E, Yazidjoglou A, Brown S, Nguyen M, Martin M, Beckwith K, Daluwatta A, Campbell S, Joshy G. [https://www.nhmrc.gov.au/sites/default/files/documents/attachments/ecigarettes/Electronic_cigarettes_and_health_outcomes_%20systematic_review_of_evidence.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]. Report for the Australian Department of Health. National Centre for Epidemiology and Population Health, Canberra: April 2022. | *Referring to: Banks E, Yazidjoglou A, Brown S, Nguyen M, Martin M, Beckwith K, Daluwatta A, Campbell S, Joshy G. [https://www.nhmrc.gov.au/sites/default/files/documents/attachments/ecigarettes/Electronic_cigarettes_and_health_outcomes_%20systematic_review_of_evidence.pdf Electronic cigarettes and health outcomes: systematic review of global evidence]. Report for the Australian Department of Health. National Centre for Epidemiology and Population Health, Canberra: April 2022. | ||
===2022: Comments RE: [https://pubpeer.com/publications/727EA7B64FB27270F20717729D7629 Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice]=== | |||
*Although this new research from Moshensky et al., does add to the scientific literature about previously marketed JUUL products, we believe the conclusions presented in the manuscript are not adequately supported by the study data. In addition, the lack of quantitative data on actual dosing limits the ability to establish relevance to potential human exposures from product use. Furthermore, the lack of a comparison against the effects of tobacco smoke limits the ability to evaluate these study findings in the context of the tobacco product risk continuum, and risk relative to use of combusted cigarettes. (Weil) | |||
*Referring to: Moshensky A, Brand CS, Alhaddad H, Shin J, Masso-Silva JA, Advani I, Gunge D, Sharma A, Mehta S, Jahan A, Nilaad S, Olay J, Gu W, Simonson T, Almarghalani D, Pham J, Perera S, Park K, Al-Kolla R, Moon H, Das S, Byun MK, Shah Z, Sari Y, Heller Brown J, Crotty Alexander LE. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice. Elife. 2022 Apr 12;11:e67621. PMID: 35411847; PMCID: PMC9005188. [https://doi.org/10.7554/elife.67621 doi: 10.7554/eLife.67621] | |||
==Respiratory== | ==Respiratory== | ||
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=Suggestions to add to this page= | =Suggestions to add to this page= | ||
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==Paper: [https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.29148 Downregulation of miR-218 by nicotine promotes cell proliferation through targeting CDK6 in non–small cell lung cancer]== | |||
*[https://pubmed.ncbi.nlm.nih.gov/38577886/ Retraction] | |||
*[https://pubpeer.com/publications/D500DE74010B291A7B27CBB9083FEA PubPeer] | |||
==Paper: [https://pubs.acs.org/doi/10.1021/acs.chemrestox.1c00253 Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry]== | ==Paper: [https://pubs.acs.org/doi/10.1021/acs.chemrestox.1c00253 Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry]== | ||
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==Paper: [https://gh.bmj.com/content/9/2/e013866 Pharmaceuticalisation as the tobacco industry’s endgame]== | ==Paper: [https://gh.bmj.com/content/9/2/e013866 Pharmaceuticalisation as the tobacco industry’s endgame]== | ||
*Comment: [https://pubpeer.com/publications/374B1C6D333BD84814E878DF9D1611 Title: Errors in one sentence - oversights or indicators of other problems?] | *Comment: [https://pubpeer.com/publications/374B1C6D333BD84814E878DF9D1611 Title: Errors in one sentence - oversights or indicators of other problems?] | ||
==[https://www.ecigarette-research.org/research/index.php/whats-new/whatsnew-2015/233-pm A new study reports that e-cigarettes emit toxins to the environment but the authors did not really find any…]== | |||
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[[File:Retracted 2.png|center|]] | [[File:Retracted 2.png|center|]] | ||
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