Does nicotine cause mental health issues?: Difference between revisions

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==Scientific Publications - Not Youth Specific==
==Scientific Publications - Not Youth Specific==
===2014: [https://pubmed.ncbi.nlm.nih.gov/25293386/ Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium]===
*Findings from Mendelian randomisation analyses do not support a causal role of smoking heaviness in the development of depression and anxiety.
*Citation: Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., Campbell, A., Engmann, J., Mirza, S. S., Loukola, A., Laatikainen, T., Partonen, T., Kaakinen, M., Ducci, F., Cavadino, A., Husemoen, L. L. N., Ahluwalia, T. S., Jacobsen, R. K., Skaaby, T., Ebstrup, J. F., … Munafò, M. R. (2014). Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium. BMJ open, 4(10), e006141. https://doi.org/10.1136/bmjopen-2014-006141




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*As there was no association of the smoking-related rs1051730 SNP with anxiety and depression among smokers, the results suggest that smoking is not a cause of anxiety and depression.
*As there was no association of the smoking-related rs1051730 SNP with anxiety and depression among smokers, the results suggest that smoking is not a cause of anxiety and depression.
*Citation: Bjørngaard, J. H., Gunnell, D., Elvestad, M. B., Davey Smith, G., Skorpen, F., Krokan, H., Vatten, L., & Romundstad, P. (2013). The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study. Psychological medicine, 43(4), 711–719. https://doi.org/10.1017/S0033291712001274
*Citation: Bjørngaard, J. H., Gunnell, D., Elvestad, M. B., Davey Smith, G., Skorpen, F., Krokan, H., Vatten, L., & Romundstad, P. (2013). The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study. Psychological medicine, 43(4), 711–719. https://doi.org/10.1017/S0033291712001274
===2011: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139580/ Smoking Is Associated with, but Does Not Cause, Depressed Mood in Pregnancy – A Mendelian Randomization Study]===
*Our results do not support a causal role of smoking on depressed mood, but are consistent with a self-medication hypothesis, whereby smoking is used to alleviate symptoms of depression.
*Citation: Lewis SJ, Araya R, Smith GD, Freathy R, Gunnell D, Palmer T, Munafò M. Smoking is associated with, but does not cause, depressed mood in pregnancy--a mendelian randomization study. PLoS One. 2011;6(7):e21689. doi: 10.1371/journal.pone.0021689. Epub 2011 Jul 19. PMID: 21818261; PMCID: PMC3139580.


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