Richardpruen (talk | contribs) (→Sudies, Papers, Randomised Controlled Trials etc...: added paper on the use of patches with ends for smoking cessation, interestingly patches did not statistically reduce ENDS use.) |
Richardpruen (talk | contribs) (→Sudies, Papers, Randomised Controlled Trials etc...: formatting and adding comments) |
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* Jed E. Rose, Suzanne Frisbee, David Campbell, Alfred Salley, Susan Claerhout & James M. Davis Psychopharmacology (2023) | * Jed E. Rose, Suzanne Frisbee, David Campbell, Alfred Salley, Susan Claerhout & James M. Davis Psychopharmacology (2023) | ||
* Included here as it may have found ENDS use reduced or accidental quitters from NRT use. See section 1 here [[Myth: Alternative nicotine products don't help people stop smoking]]. | |||
* Electronic nicotine delivery systems (ENDS) are used by smokers seeking to reduce combustible cigarette (CC) use, but the role of nicotine replacement vs. behavioral and sensory factors is still poorly understood. We hypothesized that providing nicotine from ENDS in addition to nicotine skin patches would promote smoking reduction relative to non-nicotine control ENDS. | * Electronic nicotine delivery systems (ENDS) are used by smokers seeking to reduce combustible cigarette (CC) use, but the role of nicotine replacement vs. behavioral and sensory factors is still poorly understood. We hypothesized that providing nicotine from ENDS in addition to nicotine skin patches would promote smoking reduction relative to non-nicotine control ENDS. | ||
* The use of nicotine in ENDS led to significant reductions in smoking (ENDS nicotine vs. placebo difference in CO change = −9.2 ppm; 90% CI (−1.5 ppm, −16.9 ppm)) and was highly correlated with reductions in self-reported cigarettes per day (''r''=0.6). The effect of nicotine in nicotine patches was not statistically significant (patch nicotine vs. placebo difference in CO change = −0.1 ppm; 90% CI (−7.8 ppm, 7.6 ppm)). | * The use of nicotine in ENDS led to significant reductions in smoking (ENDS nicotine vs. placebo difference in CO change = −9.2 ppm; 90% CI (−1.5 ppm, −16.9 ppm)) and was highly correlated with reductions in self-reported cigarettes per day (''r''=0.6). The effect of nicotine in nicotine patches was not statistically significant (patch nicotine vs. placebo difference in CO change = −0.1 ppm; 90% CI (−7.8 ppm, 7.6 ppm)). | ||
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