VLN Cigarette: Difference between revisions
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===2019: [https://academic.oup.com/ntr/article/21/Supplement_1/S38/5684952 Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness]=== | ===2019: [https://academic.oup.com/ntr/article/21/Supplement_1/S38/5684952 Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness]=== | ||
*"These results suggest that a reduced-nicotine standard for cigarettes would reduce smoking among smokers with SMI. However, the lack of effect on total nicotine exposure indicates VLNC noncompliance, suggesting that smokers with SMI may respond to a reduced-nicotine standard by substituting alternative forms of nicotine." | *"These results suggest that a reduced-nicotine standard for cigarettes would reduce smoking among smokers with SMI. However, the lack of effect on total nicotine exposure indicates VLNC noncompliance, suggesting that smokers with SMI may respond to a reduced-nicotine standard by substituting alternative forms of nicotine." | ||
===2019: [https://pmc.ncbi.nlm.nih.gov/articles/PMC7297107/ Pharmacokinetic Profile of Spectrum Reduced Nicotine Cigarettes]=== | |||
*"Additional dose–response relationships have been detected on the number of cigarettes smoked per day when low and high nicotine Spectrum cigarettes are available. For example, after 7 days of smoking Spectrum cigarettes, individuals given the low-nicotine content cigarettes significantly reduced the number of experimental cigarettes smoked compared to those given the high-nicotine content research cigarettes." | |||
===2018: [https://pubmed.ncbi.nlm.nih.gov/29902305/ Nondaily Smokers' Changes in Cigarette Consumption With Very Low-Nicotine-Content Cigarettes: A Randomized Double-blind Clinical Trial]=== | ===2018: [https://pubmed.ncbi.nlm.nih.gov/29902305/ Nondaily Smokers' Changes in Cigarette Consumption With Very Low-Nicotine-Content Cigarettes: A Randomized Double-blind Clinical Trial]=== | ||
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===2009: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573966/ Toxicological Analysis of Low-Nicotine and Nicotine-Free Cigarettes]=== | ===2009: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573966/ Toxicological Analysis of Low-Nicotine and Nicotine-Free Cigarettes]=== | ||
*In summary, a toxicological analysis does not indicate that low-nicotine and nicotine-free Quest® cigarettes have less adverse toxicological effects in the laboratory than conventional cigarettes. This should draw the attention of the consumers and policy makers. A more comprehensive evaluation in smokers is expected for these new products. | *In summary, a toxicological analysis does not indicate that low-nicotine and nicotine-free Quest® cigarettes have less adverse toxicological effects in the laboratory than conventional cigarettes. This should draw the attention of the consumers and policy makers. A more comprehensive evaluation in smokers is expected for these new products. | ||
==Letters to the FDA CTP in Support or Opposition== | |||
===2025: [https://www.convenience.org/Media/Daily/2025/September/15/2-NACS-Sends-Letter-Opposing-FDA-Proposal_GR NACS Sends Letter Opposing FDA Proposal on Reduced Nicotine]=== | |||
==Statements, Official Comments, Testimony== | ==Statements, Official Comments, Testimony== | ||
===2018: [https://www.iowaattorneygeneral.gov/media/cms/Reduced_Nicotine_ANPRM_Response_180_5BB91F8E318CC.pdf ANPRM comment by Iowa AG, Tom Miller, and leading public health experts]=== | ===2018: [https://www.iowaattorneygeneral.gov/media/cms/Reduced_Nicotine_ANPRM_Response_180_5BB91F8E318CC.pdf ANPRM comment by Iowa AG, Tom Miller, and leading public health experts]=== | ||
*However, we all agree that there is one important requirement common to each of the perspectives above: that is the availability of low-risk non-combustible alternative tobacco or nicotine products that are sufficiently satisfying alternatives to cigarettes that smokers who choose to continue to use nicotine would be willing to switch to them. | *However, we all agree that there is one important requirement common to each of the perspectives above: that is the availability of low-risk non-combustible alternative tobacco or nicotine products that are sufficiently satisfying alternatives to cigarettes that smokers who choose to continue to use nicotine would be willing to switch to them. | ||
==Discussion links BLOGs, Articles, Videos, etc== | ==Discussion links BLOGs, Articles, Videos, etc== | ||
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===2022: [https://jamanetwork.com/journals/jama/article-abstract/2788548 First Modified-Risk Combusted Cigarettes Are Authorized]=== | ===2022: [https://jamanetwork.com/journals/jama/article-abstract/2788548 First Modified-Risk Combusted Cigarettes Are Authorized]=== | ||
===2021: [https://clivebates.com/twenty-reasons-to-be-sceptical-about-rules-lowering-nicotine-levels-in-cigarettes-and-what-to-do-instead/ Twenty reasons to be sceptical about rules lowering nicotine levels in cigarettes – and what to do instead]=== | |||
===2021: [https://clivebates.com/fda-spreads-confusion-about-nicotine-and-smoking/ FDA spreads confusion about nicotine and smoking]=== | ===2021: [https://clivebates.com/fda-spreads-confusion-about-nicotine-and-smoking/ FDA spreads confusion about nicotine and smoking]=== | ||