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| *Ten pregnant smokers in Burlington, VT and Baltimore, MD participated in 2017–2018. | | *Ten pregnant smokers in Burlington, VT and Baltimore, MD participated in 2017–2018. |
| *Reducing the nicotine content of cigarettes may decrease their abuse liability in pregnant smokers without causing untoward craving/withdrawal or compensatory smoking. Studies of extended exposure to VLNCs in pregnant women are warranted. | | *Reducing the nicotine content of cigarettes may decrease their abuse liability in pregnant smokers without causing untoward craving/withdrawal or compensatory smoking. Studies of extended exposure to VLNCs in pregnant women are warranted. |
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| | ===2020: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244375/ Differences in Acute Reinforcement Across Reduced Nicotine Content Cigarettes]=== |
| | *17 people completed the study. |
| | *Although replication with larger samples and longer access is needed, results indicate nicotine reduction to ≤2.3 mg/g in cigarettes would attenuate reinforcement. This choice procedure may efficiently inform future clinical trials to assess relative reinforcing effects of smoking reduced nicotine cigarettes. |
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