Nicotine - Retracted Studies, Papers, and Articles: Difference between revisions

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*"​It is literally true that they "find no evidence...", but that is because this study is completely ill-suited to drawing any policy conclusions about e-cigarettes and COPD. Despite hinting at the limitations of cross-sectional data, the authors draw a negative-sounding conclusion without addressing the key question of how respiratory health changes for a given smoker who uses e-cigarettes to quit or cut down once they are ill from smoking or as a way of preventing COPD." (Bates)
*"​It is literally true that they "find no evidence...", but that is because this study is completely ill-suited to drawing any policy conclusions about e-cigarettes and COPD. Despite hinting at the limitations of cross-sectional data, the authors draw a negative-sounding conclusion without addressing the key question of how respiratory health changes for a given smoker who uses e-cigarettes to quit or cut down once they are ill from smoking or as a way of preventing COPD." (Bates)
*Referring to: Bowler RP, Hansel NN, Jacobson S, Graham Barr R, Make BJ, Han MK, O'Neal WK, Oelsner EC, Casaburi R, Barjaktarevic I, Cooper C, Foreman M, Wise RA, DeMeo DL, Silverman EK, Bailey W, Harrington KF, Woodruff PG, Drummond MB; for COPDGene and SPIROMICS Investigators. Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts. J Gen Intern Med. 2017 Dec;32(12):1315-1322. doi: 10.1007/s11606-017-4150-7. Epub 2017 Sep 7. PMID: 28884423; PMCID: PMC5698219.
*Referring to: Bowler RP, Hansel NN, Jacobson S, Graham Barr R, Make BJ, Han MK, O'Neal WK, Oelsner EC, Casaburi R, Barjaktarevic I, Cooper C, Foreman M, Wise RA, DeMeo DL, Silverman EK, Bailey W, Harrington KF, Woodruff PG, Drummond MB; for COPDGene and SPIROMICS Investigators. Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts. J Gen Intern Med. 2017 Dec;32(12):1315-1322. doi: 10.1007/s11606-017-4150-7. Epub 2017 Sep 7. PMID: 28884423; PMCID: PMC5698219.
===2017: [https://pubpeer.com/publications/E5B66481CC847E532FEDB066434E92 Hidden formaldehyde in e-cigarette aerosols]===
*"The problem for the authors is that cancer is a human condition and their calculation is based exposures measured by a lab machine in conditions that no humans would be able to tolerate." (Bates)
*See also: [https://pubpeer.com/publications/5D8FB0EB72850380D1A37DAA2097D6 PubPeer 2015-2017]
**"Although Jensen et al. mentioned in the 2015 NEJM research letter that the health risks of formaldehyde hemiacetal inhalation are unknown ("How formaldehyde-releasing agents behave in the respiratory tract is unknown..."), they made a calculation that the formaldehyde-attributable cancer risk from e-cigarette use is 5 to 15 times higher than from long-term smoking. These two statements are clearly contradictory, and the calculation of any cancer risk from formaldehyde hemiacetal emissions is invalid since no such risk has been established for these compounds." (Farsalinos)
*See also: [https://pubmed.ncbi.nlm.nih.gov/28864295/ replication study]
**"The high levels of formaldehyde emissions that were reported in a previous study were caused by unrealistic use conditions that create the unpleasant taste of dry puffs to e-cigarette users and are thus avoided." (Farsalinos, Voudris, Spyrou, Poulas)
*See also 2015: [https://retractionwatch.com/2015/09/11/researchers-call-for-retraction-of-nejm-paper-showing-dangers-of-e-cigarettes/ Researchers call for retraction of NEJM paper showing dangers of e-cigarettes]
**Links to the efforts to have the referenced paper retracted.
*Referring to: Jensen RP, Luo W, Pankow JF, Strongin RM, Peyton DH. Hidden formaldehyde in e-cigarette aerosols. N Engl J Med. 2015 Jan 22;372(4):392-4. doi: 10.1056/NEJMc1413069. PMID: 25607446.


===2016-2020: [https://pubpeer.com/publications/E2628F04937D0DBD870E115CB41C8B E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis]===
===2016-2020: [https://pubpeer.com/publications/E2628F04937D0DBD870E115CB41C8B E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis]===