VLN Cigarette: Difference between revisions

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===2018: [https://jamanetwork.com/journals/jama/article-abstract/2698925 Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure]===
===2018: [https://jamanetwork.com/journals/jama/article-abstract/2698925 Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure]===
*In this study, compared with gradual nicotine reduction, immediate reduction was associated with lower toxicant exposure across time, smoking fewer CPD (cigarettes per day), greater reduction in dependence, and more cigarette-free days. However, the immediate reduction in nicotine caused greater withdrawal symptoms, greater use of nonstudy cigarettes, and higher drop-out rates.
*In this study, compared with gradual nicotine reduction, immediate reduction was associated with lower toxicant exposure across time, smoking fewer CPD (cigarettes per day), greater reduction in dependence, and more cigarette-free days. However, the immediate reduction in nicotine caused greater withdrawal symptoms, greater use of nonstudy cigarettes, and higher drop-out rates.
===2018: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986583/ Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence]===
*"Thus, a reduced-nicotine standard for cigarettes produced a relatively mild and temporary increase in withdrawal among non-treatment seeking smokers."


===2017: [https://www.sciencedirect.com/science/article/abs/pii/S0091743516304510 U.S. adults' addiction and harm beliefs about nicotine and low nicotine cigarettes]===
===2017: [https://www.sciencedirect.com/science/article/abs/pii/S0091743516304510 U.S. adults' addiction and harm beliefs about nicotine and low nicotine cigarettes]===