VLN Cigarette: Difference between revisions

Line 74:

*17 people completed the study.

*Although replication with larger samples and longer access is needed, results indicate nicotine reduction to ≤2.3 mg/g in cigarettes would attenuate reinforcement. This choice procedure may efficiently inform future clinical trials to assess relative reinforcing effects of smoking reduced nicotine cigarettes.

===2020: [https://www.mdpi.com/1660-4601/17/19/7047 Comparison between Gradual Reduced Nicotine Content and Usual Nicotine Content Groups on Subjective Cigarette Ratings in a Randomized Double-Blind Trial]===

*"Findings from our study revealed that consistent significant differences between the RNC and the UNC treatment groups started to occur at visit 6 with 1.4 mg nicotine/cigarette. The most consistent differences occurred at visits 8 and 9 when the RNC group was smoking VLNC cigarettes (0.2 mg nicotine/cigarette). The study indicates that even with reduced nicotine, cigarettes still provide some pleasurable and reinforcing effects. Subjects using RNC stated they were less likely to purchase RNC cigarettes, which would facilitate the goal of a nicotine reduction policy, but also points to the need to reduce access to black market high nicotine cigarettes. Understanding the impact of nicotine reduction on subjective effects through cigarette evaluation and liking scales would provide valuable information and possible direction to the FDA on implementing a nicotine reduction policy for cigarettes."

===2020: [https://www.ingentaconnect.com/contentone/psp/hbpr/2020/00000007/00000006/art00004 Measuring Support for Requiring Reduced Nicotine Cigarettes: Issues with Questions, Answers, and Respondents]===

@@ Line 74: / Line 74: @@
 *17 people completed the study.
 *Although replication with larger samples and longer access is needed, results indicate nicotine reduction to ≤2.3 mg/g in cigarettes would attenuate reinforcement. This choice procedure may efficiently inform future clinical trials to assess relative reinforcing effects of smoking reduced nicotine cigarettes.
+===2020: [https://www.mdpi.com/1660-4601/17/19/7047 Comparison between Gradual Reduced Nicotine Content and Usual Nicotine Content Groups on Subjective Cigarette Ratings in a Randomized Double-Blind Trial]===
+*"Findings from our study revealed that consistent significant differences between the RNC and the UNC treatment groups started to occur at visit 6 with 1.4 mg nicotine/cigarette. The most consistent differences occurred at visits 8 and 9 when the RNC group was smoking VLNC cigarettes (0.2 mg nicotine/cigarette). The study indicates that even with reduced nicotine, cigarettes still provide some pleasurable and reinforcing effects. Subjects using RNC stated they were less likely to purchase RNC cigarettes, which would facilitate the goal of a nicotine reduction policy, but also points to the need to reduce access to black market high nicotine cigarettes. Understanding the impact of nicotine reduction on subjective effects through cigarette evaluation and liking scales would provide valuable information and possible direction to the FDA on implementing a nicotine reduction policy for cigarettes."
 ===2020: [https://www.ingentaconnect.com/contentone/psp/hbpr/2020/00000007/00000006/art00004 Measuring Support for Requiring Reduced Nicotine Cigarettes: Issues with Questions, Answers, and Respondents]===