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**“The comparison between mice breathing vapour and mice breathing air is not statistically significant. There is no sample size justification and no power calculation. There is no message to the public here – I suspect these results are just noise.” (Britton) | **“The comparison between mice breathing vapour and mice breathing air is not statistically significant. There is no sample size justification and no power calculation. There is no message to the public here – I suspect these results are just noise.” (Britton) | ||
**“The study has unclear relevance for human vapers. Rodents were exposed to what are for them huge concentrations of chemicals that bear no resemblance to human exposure from vaping. Several animals in fact died during these exposures. The authors assigned the effects they observed to a carcinogen NNK – but NNK has been measured before in human vapers, and it is known that exposure from vaping is either negligible or none.” (Hajek) | **“The study has unclear relevance for human vapers. Rodents were exposed to what are for them huge concentrations of chemicals that bear no resemblance to human exposure from vaping. Several animals in fact died during these exposures. The authors assigned the effects they observed to a carcinogen NNK – but NNK has been measured before in human vapers, and it is known that exposure from vaping is either negligible or none.” (Hajek) | ||
*Referring to: Tang MS, Wu XR, Lee HW, Xia Y, Deng FM, Moreira AL, Chen LC, Huang WC, Lepor H. Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21727-21731. doi: 10.1073/pnas.1911321116. Epub 2019 Oct 7. Erratum in: Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22884. PMID: 31591243; PMCID: PMC6815158. | *Referring to: Tang MS, Wu XR, Lee HW, Xia Y, Deng FM, Moreira AL, Chen LC, Huang WC, Lepor H. Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21727-21731. [https://pubmed.ncbi.nlm.nih.gov/31591243/ doi: 10.1073/pnas.1911321116]. Epub 2019 Oct 7. Erratum in: Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22884. PMID: 31591243; PMCID: PMC6815158. | ||
===2017: RE: [https://pubpeer.com/publications/41F6EA57D0803EEE9DF65162DF0097 Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts]=== | ===2017: RE: [https://pubpeer.com/publications/41F6EA57D0803EEE9DF65162DF0097 Electronic Cigarette Use in US Adults at Risk for or with COPD: Analysis from Two Observational Cohorts]=== | ||
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