Richardpruen (talk | contribs) (Add a cardiovascular section and paper on the safe use of nicotine patches to promote blood vessel formation.) |
Richardpruen (talk | contribs) (→Cognitive / IQ / Memory: Add study showing that the cognitive benefits of vaping are the same as cigarettes; thus, vapes provide a vastly safer, acceptable alternative to cigarettes.) |
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='''Cognitive / IQ / Memory'''= | ='''Cognitive / IQ / Memory'''= | ||
=== 2024: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10998423/ An exploratory, randomised, crossover study to investigate the effect of nicotine on cognitive function in healthy adult smokers who use an electronic cigarette after a period of smoking abstinence] === | |||
* Whilst it is known that smoking is a leading avoidable cause of diseases including cardiovascular disease, lung disease and cancer, smoking prevalence in the majority of countries remains at 10–40% [1]. Despite the aforementioned health consequences being widely documented and smoking cessation medications having been available for several decades [2], smoking cessation rates remain generally low; in the US for example, based on data from 2018, successful rates were around 7.5% per year | |||
* A significant improvement in sustained attention task performance was observed following use of both the nicotine containing e-cigarettes and combustible cigarette compared to no product use. Additionally, there were no significant differences between the nicotine containing products, indicating that nicotine use enhanced sustained attention regardless of delivery format. Nicotine containing e-cigarette and combustible cigarette use also significantly improved overall mood of participants compared to no product use, with no significant differences observed between the nicotine containing products. Nicotine containing e-cigarette and combustible cigarette use significantly reduced smoking urges compared to no product use, though combustible cigarette use elicited the greatest reduction in smoking urges. | |||
* Conclusion | |||
** Overall, the nicotine containing products improved sustained attention and mood while reducing smoking urges, with the studied e-cigarettes having comparable effects to combustible cigarettes across the assessed cognitive parameters and mood measures. These results demonstrate the potential role of e-cigarettes to provide an acceptable alternative for combustible cigarettes among people who would otherwise continue to smoke. | |||
* The study was an exploratory, randomised, partially-blinded, single-centre, five-arm crossover trial. It was registered prospectively on ISRCTN (ISRCTN35376793) and received ethical approval from the ''Wales Research Ethics Committee 1'' (Cardiff, UK; reference 21/WA/0095). The research was performed in accordance with the Declaration of Helsinki (2013), Good Clinical Practice and applicable regulatory requirements. | |||
* Harry J. Green, Olivia K. O’Shea, Jack Cotter, Helen L. Philpott, and Nik Newland. Harm Reduct J. 2024; 21: 78. Published online 2024 Apr 6. doi: 10.1186/s12954-024-00993-0 PMCID: PMC10998423 | |||
* Supplementary material: | |||
** [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10998423/bin/12954_2024_993_MOESM1_ESM.docx Summary of the Cambridge Neuropsychological Test Automated Battery (CANTAB) – Task and key outcome measure descriptions.] (word document) | |||
=== 2023: [https://www.frontiersin.org/articles/10.3389/fnins.2023.1252705/full Editorial: Nicotine and its derivatives in disorders of cognition: a challenging new topic of study] === | === 2023: [https://www.frontiersin.org/articles/10.3389/fnins.2023.1252705/full Editorial: Nicotine and its derivatives in disorders of cognition: a challenging new topic of study] === | ||
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