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Twitter [http://twitter.com/pruenrichard @pruenrichard] | Twitter [http://twitter.com/pruenrichard @pruenrichard] | ||
Below are letters and documents sent in advocacy efforts as a record and should anyone wish to use them for ideas. These are my efforts and do not necessarily reflect the views of the wiki or other users. | |||
[[File:FDA comment.pdf|thumb|alt=Comment on R-U FDA review |Comment on R-U FDA review ]] | [[File:FDA comment.pdf|thumb|alt=Comment on R-U FDA review |Comment on R-U FDA review ]] | ||
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[[File:Letter sec state health and social care 14 March 2024.pdf|thumb|alt=Subject: Youth vaping Please see the above graph, so far regular use (greater than once a week) is not high and may be displacing cigarettes, cigarettes are the worlds most deadly consumer product. Infrequent and trial use (once in 30 days, or ever use) while undesirable does not lead to dependence, only those in the graph above can possibly be ‘hooked’, but not all will be. I do not think young people should be encouraged to vape, but I would like to know your answer to one question, please. If a young person is determined to use nicotine, would you advise them to smoke cigarettes instead of safer alternatives, and a what age should harm reduction products like vaping be made available. I look forward to receiving your answer. Please feel free to ask others what they think should be done. Personally I feel the situation in Sweden is close to the best balance, accepting some use of low risk Snus, in order to reduce the uptake of deadly smoking. This will take effect far faster than the generational tobacco ban, Sweden will be a non smoking nation this year, although nicotine use remains, they have the lowest cancer rate in Europe. The UK can easily and quickly achieve the same with vaping. I note also Sweden reduced the tax on Snus to accelerate uptake. Yours sincerely, Richard Pruen|Letter sec state health and social care 14 March 2024]] | [[File:Letter sec state health and social care 14 March 2024.pdf|thumb|alt=Subject: Youth vaping Please see the above graph, so far regular use (greater than once a week) is not high and may be displacing cigarettes, cigarettes are the worlds most deadly consumer product. Infrequent and trial use (once in 30 days, or ever use) while undesirable does not lead to dependence, only those in the graph above can possibly be ‘hooked’, but not all will be. I do not think young people should be encouraged to vape, but I would like to know your answer to one question, please. If a young person is determined to use nicotine, would you advise them to smoke cigarettes instead of safer alternatives, and a what age should harm reduction products like vaping be made available. I look forward to receiving your answer. Please feel free to ask others what they think should be done. Personally I feel the situation in Sweden is close to the best balance, accepting some use of low risk Snus, in order to reduce the uptake of deadly smoking. This will take effect far faster than the generational tobacco ban, Sweden will be a non smoking nation this year, although nicotine use remains, they have the lowest cancer rate in Europe. The UK can easily and quickly achieve the same with vaping. I note also Sweden reduced the tax on Snus to accelerate uptake. Yours sincerely, Richard Pruen|Letter sec state health and social care 14 March 2024]] | ||
[[File:Letter sec state health and social care 11 May 2024.pdf|thumb|alt=Subject: Tobacco and vapes bill Dear Victoria Atkins, I am contacting you as a vaping consumer, and advocate for saving lives, vaping saved my life (happy to share medical records to prove that) and I aim to pass that on to as many as possible, I am not paid in any way by anyone to do so. I was disturbed to hear some of the testimony given in parliament, much of the information was incorrect, or deliberately misleading. This is not good enough when debating a serious matter of health, accurate and science backed information is critical to saving lives. I would like an answer to the following question: What was the reason to justify excluding stakeholders, the users of vaping products, other safer tobacco products, and even people who smoke? User funded charities such as New Nicotine Alliance, who take no money from the tobacco or vaping industry should have been consulted. Users themselves or NNA would have been able to counter some of the poor information given and also to provide a view from those directly affected by the legislation being discussed. Much of the information could have been corrected, quickly and easily. The main issues with the unopposed debate (no stakeholder representative, or consideration given to stakeholders, it seems); the conflation of illegal/criminal imports of untested and illegal drug products, and legal UK nicotine vaping; the lack of separation between the independent vaping industry and tobacco multinationals (they are not the same thing); the potential to harm the UK government stop to swap scheme (saving lives of people who smoke now, not a future population, years from now)… I could go on, but others like UK Vaping Industry Association have pointed out the issues, no need for a repeat. My most important question; What is being done to ensure that stakeholders are heard, and the users of these products are not swept aside? Particularly what is being done to ensure false/misleading statements are not made to parliament by the experts, or that at least someone is included on behalf of users to set the record straight? I look forward to your responses. Yours sincerely, Richard Pruen|Letter sec state health and social care 11 May 2024]] | |||
[[File:Draft redact address letter PM 8th Jul 2024.pdf|thumb|alt=Subject: The ban on disposable cigarettes / vaping in general | |||
Dear Prime Minister, | |||
I am a consumer advocate for vaping (15 years and a vaper for 16), and I do not use disposables beyond experimenting to see what they are like. I am also an engineer. I have previously worked in the vaping industry, testing against the standards for vaping products, and owned a now-closed company, BTC Battery Testing LTD (closed 2016). I am a consumer now and take no money from any industry, charity, or government scheme. Currently, I care for my mother, who suffers from vascular dementia, and as such, I volunteer my spare time to the cause of THR. I also advocate for smoking cessation in sufferers of severe mental health conditions. ASH UK funds the group, but I do not take any payment for my time. Regarding the subject. Might I remind you that Australia has already taken this path? An effective ban, over 80 fire bombings, at least three gang-style murders, and a rampant illegal trade have resulted? It simply won’t work. The prohibitionist faction has played on children starting using these products, and may have convinced you that a ban is enforceable; sadly, if Australia cannot do it, the proximity of Europe means less chance here. I am simply being realistic. The best, perhaps only, way to control the illicit trade is to make sure there is a legal trade that makes it less profitable; the US abandoned alcohol prohibition in favour of this. Please, however, remain focused on preventing harm; having the only source of disposable vapes (sorry to say this, but it is true) that adolescents could buy, being from a ‘dealer’ who might supply other illicit substances, is not safer! At least if they are from a shop selling tested, safe devices, then that is a vast reduction in harm already, avoiding interaction with drug dealers. I prefer every shop to follow the law, but as we know, not everyone will. Adolescents might also sample smoking, especially if they sensibly avoid illicit substance dealers; this, too, is not exactly a win, smoking being deadly and carcinogenic. Those diverted from cigarettes face a much lower risk of cancer and other smoking-related diseases. It is a fact that zero deaths have been caused by vaping a regulated nicotine product; among around 82 million users worldwide, the EVALI deaths all resulted from an illegal trade in THC vaping in the US (different chemistry and devices, incompatible with nicotine vapes). I favour regulations to encourage the use of rechargeable vapes. However, even disposables can be recycled; these are far superior to cigarette filters; filter tips are nearly impossible to recycle and will be in the environment for years. Exceptions should be made for disabled people (unable to fill or use pods) in secure mental health care/prisons; here, disposable tamper-resistant devices are safer. However, legislation should favour the refillable and reusable vapes that are most environmentally sound; disposables can be discouraged without a ban. Please see the graph. So far, regular use is not high and may be displacing cigarettes. Sensible regulations to keep it that way would be welcome. A few truths to bear in mind: The use of the word ‘children’ is a deliberate tactic to tug on heart strings, more correctly teens particularly adolescents are at risk from experimenting with vapes and other adult things, harm reduction still applies, beer is safer than vodka, vapes are vastly safer than cigarettes. Infrequent trial use isn’t the best indicator of dependence (once in 30 days), better is once a week or more. To risk dependence you need to be regularly vaping. The harm from vaping is low enough it is right to argue against the use of addiction, since the DSM-5 definition requires significant harm, dependence is more correct because it can be hard to stop. Vaping allows users to taper nicotine so less than cigarettes. Millions of lives are at stake, billions of pounds the NHS spend on cancer and other smoking related treatments that could be eliminated, smoking is the leading cause of preventable death, vaping regulated nicotine products, zero deaths in 20 years. The less popular you make vaping, the more popular smoking will become, they are substitutes. When you ban things; illicit markets form, they have no reason to follow age of sale or other rules, this risks making things worse not better (Australia demonstrates this). The generational ban while it sounds good, kicks the can into the future, vaping is reducing smoking right now, and more effort is required to target older adults, they are the ones facing smoking related diseases imminently, switching them to vapes is a huge immediate benefit the generational ban could never deliver. I would like to hear your thoughts, I will be happy to provide evidence to support what I have said, if required for any point please let me know. You promised your government would work for us, and would look after our health and well-being, here is a way to prove you will listen, many lives can be saved. If there is one single study I think most important: Comparison of biomarkers of exposure among US adult smokers, users of electronic nicotine delivery systems, dual users and nonusers, 2018–2019. For every harmful or potentially harmful compound, vapers look exactly like non-users. Thank you for your time, I have tried to be brief as you must be busy, but welcome questions should you have any. Yours sincerely, Richard Pruen P.S. My story: Why I do this? I started vaping in 2008 when it was relatively new, I had at this point given up trying to stop smoking, having tried everything. I intended to vape where I was unable to smoke. To my surprise in March of 2009 I discovered I had money budgeted for cigarettes that was unspent, this was how I discovered I had accidentally given up smoking. In 2010 I watched my father die from cancer, smoking 20/day didn’t help, although as a firefighter there is occupational risk also. My health improved substantially over the first 5 years, and at 15 years vaping I had an MRI due to aortic aneurysms running in the family (my father had one repaired), my lungs where those of a non smoker, doctors where unable to find any sign I vape. Put simply vaping saved my life and I would like pass that forward, partly in memory of my father, he was a firefighter and lived to save lives. |draft letter to new PM for 8th JUL]] | |||
[[File:Draft redact address letter wes sweeting 15th Jul 2024.pdf|thumb|alt=Subject: Tobacco and vapes bill | |||
Dear Wes Sweeting, | |||
I am contacting you as a vaping consumer and advocate for saving lives; vaping saved my life (I am happy to share medical records to prove that), and I aim to pass that on to as many as possible. I am not paid in any way by anyone to do so. I have worked in the vaping industry, helping to develop standards and testing against them (I ran BTC battery testing until 2016). This was good for consumer safety, but the industry did not necessarily favour it. I am also part of a group funded by ASH advocating for smoking cessation in people living with severe mental illness; 40% smoke cigarettes, double the national number. | |||
I was disturbed to hear some of the testimony given in parliament, mainly by the previous government. Much of the information was incorrect or deliberately misleading. You must do better when debating a serious health matter; accurate and science-backed information is critical to saving lives. You should be using the research OHID paid for using taxpayers' money, not anecdotal (often second-hand) accounts from teaching staff or parents frightened by the media (more on that below). | |||
Before proceeding with further legislation, you must pause and ensure stakeholders (particularly end users) are appropriately consulted. Without accurate and proper information, bad legislation will result, like Australia and the prescription model (now dropped, and pharmacy only, also likely to fail) Will Australia's tightened prescription system reduce nicotine vaping among young people? wiley.com and others show the policy failed, and instead 90% supply was from illegal sales controlled by organised crime. At the time of writing this, there have been more than 80 fire-bombings, three murders, and many gang ‘turf-wars’ in Australia. We do not need to bring that here. | |||
Sadly, there is a lot of misinformation being pushed in the media regarding children using these products; the use of ‘children’ is deceptive, even using the over-wide definitions that are often cited; children are not the population at risk. Sales are already illegal to those under 18; advertising to such age groups is also banned, and advertising is generally restricted. Please see my letter to the PM available from my wiki user page (direct link) https://safernicotine.wiki/mediawiki/index.php/File:Draft_redact_address_letter_PM_8th_Jul_2024.pdf. Adolescents are the population who might take up vaping, they might also take up smoking (far more deadly), or experiment with other adult things. It is a part of growing up, and if you prevent the less harmful options, adolescents will probably do more risky things. | |||
I agree that you should keep a close eye on frequent vaping among adolescents; thankfully, that remains low and does not show worrying trends (please see the graph in the letter to PM above). Experimentation with vaping is preferable to cigarettes, and still, too many are starting to smoke tobacco. Vaping is unlikely to cause deaths, at least, unlike tobacco, and has (with open devices) the off-ramp of tapering nicotine slowly (around a third of folks quitting smoking with vapes also stop vaping this way; see ONS data). | |||
It is essential to accept the vastly lower risk when considering legislation that will steer adolescents in a particular direction. Assuming they will do extra homework if they can’t experiment is faulty. They will likely do something more risky instead, such as alcohol. Alcohol, for example, results in accidents, intoxication and deaths. This is sadly human nature, and harm reduction at least keeps the risks as low as possible. | |||
It is also vital to ensure that illicit vapes and illegal sales are kept to a minimum; buying vapes from ‘dealers’ opens all manner of unwanted possibilities, including other more harmful illegal drugs being offered. Thus, great care is needed to avoid a ban on a product type resulting in supply shifting to criminal-controlled illicit sales. There is already too much of this with over-strength/over-capacity disposable vapes; outright bans on disposables will make this far worse. This will require some subtlety and care in regulations to address the issue. Instead of a ban, having the price include the cost of disassembly recovery and recycling might better direct sales to refillable and, thus, much more environmentally friendly devices. The extra complexity of using a pod device is slight, so a small nudge is likely required for most consumers to shift to a more environmentally responsible product. You need to consider things carefully before doing anything and look at the unintended consequences that might occur. | |||
In only five years, New Zealand halved its smoking rate (now approaching 5%). https://www.scoop.co.nz/stories/WO2407/S00138/caphra-calls-on-asia-pacific-governments-to-allow-sale-of-oral-nicotine-products.htm The government there promoted vaping more than the UK government. For comparison, Canada taxes and does not promote vaping, and the smoking rate has remained stable. Sweden recently reduced the tax on Snus in a bid to increase switching (they are about to drop below 5% also) and has had great success with a THR product in Snus. | |||
In Sweden, the use of nicotine is about the same as in the EU as a whole, but the rates of cancer are lower, particularly in men, since they switched earlier, and the trend is now apparent in the data. It is worth looking at Sweden because it has had a harm-reduction product for a long time, and trends and population data are readily available. It is obvious that nicotine is not a problem; it is combusted tobacco, particularly cigarettes; switching existing users to safer products is the priority; you can save vast numbers of lives and treatment costs. I suggest you research the history of THR in Sweden, allowing users to initiate nicotine use with a safer product works; they have the lowest cancer rates in the EU by a good margin. | |||
It is essential to be honest when looking at nicotine; it has benefits for some people; for ADHD, it is an effective treatment. I can help with other things, schizophrenia and depression. There is a list of peer-reviewed science here: https://safernicotine.wiki/mediawiki/index.php/Nicotine_therapeutic_benefits. Not to mention that every military in the world included nicotine in rations and snuff for submariners (since smoking was not possible due to hydrogen from batteries); they would not have gone to such expense if it was not beneficial to highly stressed young soldiers. These reasons mean that some people will use nicotine, so safer options are a win. Nicotine cannot be eradicated as some would wish. Trying to do so will result in uncontrolled illegal sales and crime (please see Australia if you have any doubts). To do the right thing and reduce harm as far as possible, you must look at all this and do your best. There is no clear path; there are always unintended consequences (thankfully, safer nicotine products are very non-deadly compared to cigarettes, so the remaining risk equates to being dependent (this happens with caffeine/coffee/energy drinks with little fuss)). So you have a chance to do what is right by the people you work for, and the NHS, even if it doesn’t fit entirely with popular opinion (partly due to worldwide campaigns by Mike Bloomberg and associated NGOs, they were caught trying to influence government https://mb.com.ph/2021/08/30/local-anti-vaping-groups-also-received-millions-of-grant-money-from-bloomberg/ Bloomberg has also stated “I don’t care if vapes are safer. I want them shut down no matter what” Public health heavyweights and scientists alike have offered to present evidence proving the good from vaping/THR, but have been ignored (repeatedly), Bloomberg’s view seems based not on data, but ideology. | |||
Needless to say, the tobacco and vapes bill is generational prohibition; by the modelling done, it will not do anything until it restricts sales (2040 before results are seen); it risks creating an illegal market and other prohibition-related problems; we can look to Australia to see the sorts of things to expect. Getting vapes out to older adult cigarette users will give results from day one; as soon as someone switches to vaping, the risk of cancer and disease begins to fall. That relieves pressure for treatment from the NHS, which can only be good. | |||
As I see it, you need to stop and take a hard look at the sin tax (it will put folks off switching and give the impression vapes are as bad as smoking) and the tobacco and vapes bill, then it shouldn’t be challenging to find something better. I think vapes should remain tax-free to encourage switching. However, users might put up with a small amount to improve enforcement of underage sales and illegal vapes. (Though there are things that can be done to reduce the waste from disposables by a factor of 10) some ideas in this letter https://safernicotine.wiki/mediawiki/index.php/File:Email_to_appg_vaping_28th_Feb_2023.pdf | |||
One last point, the UN considers harm reduction for drug users to be a human right, and nicotine is a drug. This means that because harm reduction options exist, all with vastly lower risk than cigarettes, you must try to make them available to those at risk from the more harmful combusted tobacco. | |||
Please feel free to ask questions. I will always try to help if possible. Likewise, if you require evidence to support anything I have said, please ask. Alternatively, you can verify with your own research if you wish. Yours sincerely,Richard Pruen|Draft letter Wes Sweeting]] | |||
[[File:Email 6th sept DHSC reply.pdf|thumb|alt=Sirs, Please find my reply inline in answer to your comments below. It is rather long, but a great deal of misinformation needs correcting. On Fri, 2024-09-06 at 10:51 +0000, Department of Health and Social Care wrote: Our ref: DE-1524319 Dear Mr Pruen, Thank you for your correspondence of 5 August about vaping. I have been asked to reply. I appreciate your concerns. The Government recognises the role that vapes can play as a smoking quit aid and it is not its intention to restrict the accessibility of vapes to adults in the upcoming Bill. Any measures brought forward through the upcoming Bill will be designed to curb youth vaping whilst having a minimal impact on adult vapers. The number of children vaping has tripled in the last three years, with one in five having used a vape in 2023, and the Government’s aim is to stop future generations from becoming hooked on nicotine. Regarding the number vaping, very small number tripled is a very small number, for comparison please see the following graph (30 day use for various places) this includes a lot of experimental use that does not lead to dependence, and is sadly a part of growing up, adolescents try adult things (including alcohol at higher rates than vaping, causing deaths). Vaping won't cause any deaths at least, unlike cigarettes (few but fires do happen). As can be seen the rates of infrequent use are the lowest in the UK, and highest in Australia (excluding the blip in the USA). I do not believe this is a coincidence, it reflects the regulation and illegal sales, the UK and Australia being at opposite extremes. Here in the UK vaping is regulated and most sales are legal, from shops that have every reason to restrict sales to adolescents. In Australia the product is illegal without prescription, and 92% of the supply is via illegal sales, leading to firebombings and gang warfare. Illegal sales have every incentive to break the law, and sell to anyone with the cash. Illegal products are entirely unregulated. We need to remain in control of sales, since it is working, the UK has the lowest use among adolescents. Changes risk sending more sales to the illegal market, and reducing control over sales. This will have the opposite effect to the one you intend and result in more sales being illegal and thus more sales to underage. More enforcement of the existing rules, and work to reduce illegal sales would be welcome, and I suggest more useful than further restrictions in remaining in control. Absolutely do not follow Australia, that method/type of control is proven a failure. In the data above from ASH, we can see that 0.8% young people are vaping regularly having not also been a smoker, vaping is vastly safer than smoking, diverting them from cigarettes is a highly positive outcome. Given the data, and we must rely on data and facts here, all but 0.8% are diverted from cigarettes, and that means virtually no smoking naive youth are going on to regularly vape. This quite near to the ideal situation, changes in legislation that might make this worse (by increasing illegal sales) should be avoided. If it is working, don't fix it? While it is certainly true that adults prefer fruit and sweet flavours, many flavours on the market are overly appealing to children.Evidence shows that children are attracted to the fruit and sweet flavours of vapes, both in their taste and smell, as well as how they are described. Many flavours have attractive wording and names that entice children to try vaping, such as ‘gummy bear’ and ‘rainbow burst’. Nonsense, gummy bears are a sweet from my childhood, they may exist still, but I would buy that, I contest that is targeted at memories of adults. You might have more information on this, you should speak to the actual consumers of the product before jumping to easy sounding conclusions. New Nicotine Alliance are a charity funded exclusively by consumers and represent them, they would be a great point of contact. A consumer only org eliminates possible issues with manufacturer or even tobacco company influence. The Government is aware that vape flavours are an important consideration for adult smokers when seeking to quit smoking and it will carefully consider any restrictions to avoid unintended consequences. The primary purpose of the Tobacco and Vapes Bill is to reduce smoking rates by bringing forward a generational ban on the sale of tobacco, making it an offence for anyone to sell tobacco products to anyone born on or after 1 January 2009. This policy is not being implemented for vapes because the health advice is clear that vaping is less harmful than smoking; however, vaping is not risk-free and nor is the consumption of nicotine. https://x.com/JonathanFoulds/status/1829195343780819169 The tobacco part of the bill is irrelevant according to this, and economists everywhere, cigarettes are going away. By the time the generational ban has any effect, there will have been no uptake of smoking for some years, and thankfully that will result in faster reductions in death and disease. The Generational ban is too slow, no effect for more than 20 years, but thankfully, THR (tobacco harm reduction) will have more effect and way faster, it has already begun as above. Nicotinecauses addiction rapidly and can increase the risk of developing conditions such as cardiovascular disease, gastrointestinal disorder and more rapid development of some cancers. Giving up nicotine is very difficult, and withdrawal symptoms can include cravings, irritability, anxiety, trouble concentrating, headaches and other mental symptoms. Evidence also suggests that the brain in adolescence is more sensitive to the effects of nicotine, so there could be additional risks for young people. That is why it is vital that vapes are only used as a smoking cessation tool. Vapes are an effective quit tool for smokers, particularly when combined with behavioural support. Therefore, it is important that vapes remain accessible to adult smokers. The Government remains fully committed to the Swap to Stop scheme, which involves swapping cigarettes for vapes. This part is shocking, and awful both at the same time. The misinformation presented to government is terrible. There is no good evidence that nicotine outside smoking increases the risk of cardiovascular disease, in fact long term studies in Sweden show nicotine from Snus is not associated with increase in cardiovascular risk, nor with any sort of cancer. Since Snus has been popular for a long time the evidence is based on studies of the actual population, much more reliable than e.g. extrapolation from cell or animal studies. Would you provide the source of this disinformation (Cardiovascular desease, gastrointestinal desease, cancer risk), and who presented it, please? This is important, the government needs true and up to date information, and sources of poor/disinformation need to be tackled. Further there is good evidence that nicotine can treat some gastrointestinal problems, please may I have the source for your claim it is a cause. I present some peer reviewed papers below, none are industry funded. I can present more if you would like? https://academic.oup.com/ntr/advance-article-abstract/doi/10.1093/ntr/ntae193/7727428 "Despite different mechanisms of action, both ENDS and CCs attenuated on-going colon inflammation, enhanced healing and ameliorated recovery of injured intestines of DSS-treated mice and UC patients." Citation: Kastratovic N, Markovic V, Arsenijevic A, Volarevic A, Zdravkovic N, Zdravkovic M, Brankovic M, Gmizic T, Harrell CR, Jakovljevic V, Djonov V, Volarevic V. The effects of combustible cigarettes and electronic nicotine delivery systems on immune cell-driven inflammation and mucosal healing in ulcerative colitis. Nicotine Tob Res. 2024 Aug 5:ntae193. doi: 10.1093/ntr/ntae193. Epub ahead of print. PMID: 39101540. https://www.frontiersin.org/articles/10.3389/fimmu.2022.826889/full Analysis of several studies - some animal. In general, nicotine is beneficial in ulcerative colitis; in particular, nicotine transdermal patches or nicotine enemas have shown significantly improved histological and global clinical scores of colitis, inhibited pro-inflammatory cytokines in macrophages, and induced protective autophagy to maintain intestinal barrier integrity. Citation: Zhang W, Lin H, Zou M, Yuan Q, Huang Z, Pan X and Zhang W (2022) Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects. Front. Immunol. 13:826889. doi: 10.3389/fimmu.2022.826889 Acknowledgements: This work was supported by the National Natural Science Foundation of China (grant number 81903319), Natural Science Foundation of Guangdong Province of China (grant number 2021A1515011220), Administration of Traditional Chinese Medicine of Guangdong Province of China (grant number 20211008), Special Fund for Young Core Scientists of Agriculture Science (grant number R2019YJ-QG001), Special Fund for Scientific Innovation Strategy—Construction of High-Level Academy of Agriculture Science (grant number R2018YJ-YB3002), Top Young Talents of Guangdong Hundreds of Millions of Projects of China (grant number 87316004), the foundation of director of Crops Research Institute, Guangdong Academy of Agricultural Sciences (grant number 202205) and Outstanding Young Scholar of Double Hundred Talents of Jinan University of China. https://www.hindawi.com/journals/grp/2008/237185/ Smoking has a detrimental effect in Crohn's disease (CD), but this may be due to factors in smoking other than nicotine. Given that transdermal nicotine benefits ulcerative colitis (UC), and there is a considerable overlap in the treatment of UC and CD, the possible beneficial effect of nicotine has been examined in patients with Crohn's colitis. In this relatively small study of patients with active Crohn's colitis, 6 mg nicotine enemas appeared to be of clinical benefit in most patients. They were well tolerated and safe. PDF Version Citation: J. R. Ingram, J. Rhodes, B. K. Evans, and G. A. O. Thomas, Hindawi Publishing Corporation, Gastroenterology Research and Practice, Volume 2008, Article ID 237185, 6 pages, doi:10.1155/2008/237185 Acknowledgements: J. R. Ingram was supported by the Gastrointestinal Foundation Trust. SLA Pharma gave financial support to the project. The authors are indebted to Dr. J. T. Green (of Cardiff and Vale Hospitals Trust) who referred patients, and to Professor G. T. Williams (GTW) who performed all histological assessments. Regarding nicotine addiction, the DSM requires significant harm as well as the difficulty in stopping use, the safer forms of nicotine do not pose sufficient risk/harm by that definition. Tobacco when smoked certainly does pose sufficient risk, thus addiction is justified. Loss of autonomy is not sufficient harm, though it does require consideration, if it where caffine in coffee would be addictive, not the more reasonable dependency forming. For the dependency of nicotine, your information appears out of date, I will deffer to Karl Fagerstrom, world leading expert and inventor of the most used dependency test for nicotine. Karl Fagerstrom | 14 December 2013 "We used to believe that nicotine is very dependence producing, but the evidence suggests that there are a number of problems with this statement. For example, animals do not self-administer nicotine as readily as they do other dependence producing drugs such as amphetamine, cocaine, and heroin (Villegier et al. 2003); nicotine is a relatively weak reinforcer in human laboratory studies (Perkins et al. 2001); abstinent smokers seem to prefer a much reduced or nicotine free e-cigarette rather than other - often stronger - nicotine-containing products like gum; and although nicotine replacement treatment is an effective aid for quitting smoking, its efficacy is moderate even in doses that replace most or all nicotine from the cigarettes formerly used (Dale et al. 1995). There is very little to no evidence for the abuse of nicotine when not delivered in a tobacco vehicle." https://nicotinepolicy.net/authors/karl-fagerstrom/dependence-on-tobacco-and-nicotine/ The above link contains more information expanding on the above, with references. The Vaping Products Duty did not form part of the previous Government’s Tobacco and Vapes Bill. Taxation is the responsibility of HM Treasury, which ran a public consultation on the proposals for the duty from 6 March to 29 May. HM Treasury and HM Revenue and Customs are currently considering responses to that consultation. There are no plans to introduce any tax changes as part of the upcoming Bill. I hope this reply is helpful. Thank you for the reply, it remains to be seen how useful this conversation is, it depends on your willingness to accept the evidence. Evidence is changing rapidly in tobacco and nicotine, this was not always the case, for a long time tobacco was the only source of nicotine in popular use, now that has changed (for the better with safer products, mostly not from the tobacco industry of old, I would argue). Regarding the tax, it need to be considered alongside policy, it as proposed is a 'sin tax' and will result in significant increase in illegal sales as tax avoidance adds to profitability, thus crime and sales to youth, as well as dissuading adults who smoke cigarettes from switching to a product that is likely to save their life. I would remind you that 30% of vape sales are illegal, I have previously written to explain some ways to reduce the impact of vapes on the environment (by a significant ten fold) and at the same time allow regulated products to out-compete the illegal products (making illegal sales nonprofitable is the easiest/cheapest control). A link o my previous letter https://safernicotine.wiki/mediawiki/index.php/File:Email_to_appg_vaping_28th_Feb_2023.pdf Yours sincerely, Correspondence Officer Ministerial Correspondence and Public Enquiries Department of Health and Social Care --------------------------------------------------------------------- ---------------------------------------------------- Please do not reply to this email. To contact the Department of Health and Social Care, please visit theContact DHSC section on GOV.UK To receive news about DHSC: sign up to our monthly newsletter This e-mail and any attachments is intended only for the attention of the addressee(s). Its unauthorised use, disclosure, storage or copying is not permitted. If you are not the intended recipient, please destroy all copies and inform the sender by return e-mail. Any views expressed in this message are not necessarily those of the Department of Health and Social Care. Please note: Incoming and outgoing email messages are routinely monitored for compliance with our policy on the use of electronic communications. -- Richard Pruen <richard@pruen.co.uk>|reply from DHSC and reply sent]] | |||
[[File:20240908122716 FAO- Wes Streeting, Potential risk reductions.pdf|thumb|alt=Dear Wes Streeting, Given the abundance of poor information circulating in Parliament, I thought I should provide an easy to understand example of what a 95% reduction is risk product can do to cancer rates. Unlike the modelling and assumptions that appear to prop up the tobacco and vapes bill, I will provide real population data from Sweden (they started using a harm reduction strategy with snus years ago, enough that real world data is available). You can verify these graphs by visiting https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Main_Page The use of nicotine in Sweden is roughly the EU average at 22%, but much of that is a product that is similar in risk to vaping, snus is also 95% or better less risky than cigarettes. Sweden in allowing some uptake by young people has seen the reductions above, snus has substituted for a much more harmful product and overall risk has fallen dramatically as seen above. The 'not without risk' aspect of nicotine and vaping is massively overplayed, it is certainly less risky than alcohol. As you can see above so far the UK has avoided the surge in adolescent vaping seen elsewhere, there has been a rise, but according to the latest ASH data 0.8% of frequent (> once per week) users are tobacco naive, so most of the increase is diversion from smoking (a good thing since if you never inhale tobacco smoke, it cannot harm you). This begs the question; if it seems to be working, why fix it? Further restrictions will drive the product to illegal sales, and like has been seen in Australia, that results in more sales to youth, and less access for adults, exactly the opposite of the desired outcome. We already have an illegal market in oversized/over strength products roughly 30% of the market, changes will cause it to step up and supply more if it becomes profitable. Big hint here that the proposed 'sin tax' on nicotine is guaranteed to increase illegal sales. Is the tax take in the short term favourable, with the increase in illegal sales it will prompt, compared to maximising the savings to the NHS? I would strongly suggest not! Extending the swap to stop scheme, particularly to target older cigarette users will have a huge effect on the NHS, reductions like those in the Sweden graph above, would save more than 500 million a year (up to 1 billion, if we can match Sweden in 50% reduction in lung cancer). https://www.brunel.ac.uk/news-and-events/news/articles/How-much-could-the-NHS-save-if-people-had-healthier-lifestyles-Hundreds-of-millions-according-to-research#:~:text=One%20of%20my%20studies%20indicates,mouth%20cancer%20and%20heart%20disease. The reduction would help cut waiting lists by 2029 as you have promised, especially if targeting the older at risk population with swap to stop. The tobacco part of the tobacco and vapes bill, that won't have had any effect by that point, and it is likely by the time it does the cigarette market will have collapsed/changed beyond recognition. I am not sure about it collapsing, but it is becoming obvious that big changes are afoot, and it will not be good for Big Tobacco of old. I would like to ask you to be cautious of changing regulations that we already have, and that appear to be working. Also to ensure that any further measures are well though out. The tobacco generational ban, I don't think will do any vast harm at least, it might have been a really good idea if implemented 20 years ago. I would also draw your attention to this regarding misinformation https://safernicotine.wiki/mediawiki/index.php/File:Email_6th_sept_DHSC_reply.pdf I have to wonder if misinformation on vaping is from tobacco companies, since as above vaping is doing a number on them? It seems this misinformation is stated without evidence usually or highly speculative evidence (rodent studies that are unsupported by the real world data). However I am happy to provide evidence for what I have said, and welcome any questions you may have, please feel free to ask. Thank you for your time. -- Richard Pruen <richard@pruen.co.uk>|Email FAO- Wes Streeting, Potential risk reductions]] |
Latest revision as of 12:31, 8 September 2024
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The Site admin
Richard Pruen
Electrical and electronic engineer
Favorite band: Rush
Why spend so much time on this? It’s a fact that nicotine harm reduction (vaping and Snus) saved my life, this is my way to pay that forward, and pass along information on safer nicotine.
Running a site from the ground up, has proved interesting and worthwhile. Some of the things I have learned about Linux, and configuration of software for servers is only stuff you learn by doing.
I suspect the site will stick around, at least as long as it is required to provide links and info.
I might well put more info of my vaping / thr story here soon, this is just a test edit.
More test edit, and added some features, like babel to indicate users languages.
Site admin at Safer nicotine wiki.
ABOUT
Ecig user since 2008, consumer advocate for vaping and THR #VapingSavedMyLife #VapingSavesLives
Twitter @pruenrichard
Below are letters and documents sent in advocacy efforts as a record and should anyone wish to use them for ideas. These are my efforts and do not necessarily reflect the views of the wiki or other users.