ENDS Toxicity / Carcinogenic: Difference between revisions
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*Citation: Wagener TL, Floyd EL, Stepanov I, et alHave combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette usersTobacco Control 2017;26:e23-e28. | *Citation: Wagener TL, Floyd EL, Stepanov I, et alHave combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette usersTobacco Control 2017;26:e23-e28. | ||
*Acknowledgements: Intramural funds to TLW were used to complete this study. Part of TLW’s, ELF’s, LMD’s, ELL’s, NM’s, APT’s, and LQ’s salary support is provided by the Oklahoma Tobacco Research Center, which is provided funding from the Oklahoma Tobacco Settlement Endowment Trust. The Oklahoma Shared Clinical and Translational Resources (U54 GM104938) provided phlebotomy support to this study. | *Acknowledgements: Intramural funds to TLW were used to complete this study. Part of TLW’s, ELF’s, LMD’s, ELL’s, NM’s, APT’s, and LQ’s salary support is provided by the Oklahoma Tobacco Research Center, which is provided funding from the Oklahoma Tobacco Settlement Endowment Trust. The Oklahoma Shared Clinical and Translational Resources (U54 GM104938) provided phlebotomy support to this study. | ||
===2017 [https://www.frontiersin.org/articles/10.3389/fphys.2016.00663/full Trace Metals Derived from Electronic Cigarette (ECIG) Generated Aerosol: Potential Problem of ECIG Devices That Contain Nickel]=== | |||
*In general, the findings of this study suggest that the concentrations of most trace metals extracted from cigarette smoke exceed the concentrations of trace metals extracted from ECIG-generated aerosol. | |||
*Only Ni in the ECIG-generated aerosol was higher than control (smoke). The most probable source of Ni in this aerosol is the core assembly. | |||
*From this study, it is unlikely that the ECIG-generated aerosol contains enough of the other trace metals to induce significant pathology. | |||
*[https://sci-hub.se/10.3389/fphys.2016.00663 PDF Version] | |||
*Citation: Palazzolo, D. L., Crow, A. P., Nelson, J. M., & Johnson, R. A. (2017). Trace Metals Derived from Electronic Cigarette (ECIG) Generated Aerosol: Potential Problem of ECIG Devices That Contain Nickel. Frontiers in Physiology, 7. doi:10.3389/fphys.2016.00663 | |||
*Acknowledgements: This work was supported by an intramural grant from the DeBusk College of Osteopathic Medicine. | |||
===2017 [https://www.acpjournals.org/doi/10.7326/M16-1107 Nicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users]=== | |||
*Former smokers with long-term e-cigarette–only or NRT-only use may obtain roughly similar levels of nicotine compared with smokers of combustible cigarettes only, but results varied. Long-term NRT-only and e-cigarette–only use, but not dual use of NRTs or e-cigarettes with combustible cigarettes, is associated with substantially reduced levels of measured carcinogens and toxins relative to smoking only combustible cigarettes. | |||
*[https://sci-hub.se/10.7326/M16-1107 PDF Version] | |||
*Citation: Shahab, L., Goniewicz, M. L., Blount, B. C., Brown, J., McNeill, A., Alwis, K. U., … West, R. (2017). Nicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users. Annals of Internal Medicine, 166(6), 390. doi:10.7326/m16-1107 | |||
*Acknowledgement: This work was supported by Cancer Research UK (grant C27061/A16929, with additional funding from grants C1417/A14135 and C36048/A11654). Dr. Brown's post is funded by a fellowship from the Society for the Study of Addiction, and Cancer Research UK also provides support (grants C1417/A7972 and C44576/A19501). Drs. McNeill and West are part of the UK Centre for Tobacco and Alcohol Studies, which is a UK Clinical Research Collaboration Public Health Research Centre of Excellence. Funding from the Medical Research Council, British Heart Foundation, Cancer Research UK, Economic and Social Research Council, and the National Institute for Health Research under the auspices of the UK Clinical Research Collaboration is gratefully acknowledged (grant MR/K023195/1). Dr. Goniewicz was supported by the National Institute on Drug Abuse and the National Cancer Institute of the National Institutes of Health (awards R01DA037446 and P30 CA016056, respectively) and by an award from Roswell Park Alliance Foundation. | |||
==ENDS (without comparison to other products)== | ==ENDS (without comparison to other products)== | ||