Nicotine - Addiction/Dependence: Difference between revisions
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===2015: [https://www.nejm.org/doi/full/10.1056/NEJMsa1502403 Randomized Trial of Reduced-Nicotine Standards for Cigarettes]=== | ===2015: [https://www.nejm.org/doi/full/10.1056/NEJMsa1502403 Randomized Trial of Reduced-Nicotine Standards for Cigarettes]=== | ||
*In this 6-week study, reduced-nicotine cigarettes versus standard-nicotine cigarettes reduced nicotine exposure and dependence and the number of cigarettes smoked. | *In this 6-week study, reduced-nicotine cigarettes versus standard-nicotine cigarettes reduced nicotine exposure and dependence and the number of cigarettes smoked. | ||
===2010: [https://pubmed.ncbi.nlm.nih.gov/20078491/ Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation]=== | |||
*"Unlike the 0.3 mg cigarettes, 0.05 mg cigarettes were not associated with compensatory smoking behaviors. Furthermore, the 0.05 mg cigarettes and nicotine lozenge were associated with reduced carcinogen exposure, nicotine dependence and product withdrawal scores. The 0.05 mg cigarette was associated with greater relief of withdrawal from usual brand cigarettes than the nicotine lozenge. The 0.05 mg cigarette led to a significantly higher rate of cessation than the 0.3 mg cigarette and a similar rate as nicotine lozenge." | |||