Nicotine therapeutic benefits: Difference between revisions

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===2020 [https://www.sciencedirect.com/science/article/abs/pii/S000927971931734X Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model]===

*Animal study

*Conclusion: "Taken together, we demonstrated that nicotine inhibits apoptosis

*Conclusion: "Taken together, we demonstrated that nicotine inhibits apoptosis and proliferation by modulating AMPK/mTOR pathway-mediated autophagy and improves colitis severity in the DSS-induced UC mouse model. These findings provide new insights into the mechanism of nicotine treatment on UC autophagy. Further exploration of the mechanism of nicotine in autophagy and targeting factors might be considered a new approach for ulcerative colitis treatment."

and proliferation by modulating AMPK/mTOR pathway-mediated autophagy and improves colitis severity in the DSS-induced UC mouse

model. These findings provide new insights into the mechanism of nicotine treatment on UC-autophagy. Further exploration of the mechanism of nicotine in autophagy and targeting factors might be considered a new approach for ulcerative colitis treatment."

*[https://sci-hub.st/10.1016/j.cbi.2020.108943 PDF Full paper]

**Citation: Gao Q, Bi P, Luo D, Guan Y, Zeng W, Xiang H, Mi Q, Yang G, Li X, Yang B. Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model. Chem Biol Interact. 2020 Feb 1;317:108943. doi: 10.1016/j.cbi.2020.108943. Epub 2020 Jan 10. PMID: 31926917.

@@ Line 495: / Line 495: @@
 ===2020 [https://www.sciencedirect.com/science/article/abs/pii/S000927971931734X Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model]===
 *Animal study
-*Conclusion: "Taken together, we demonstrated that nicotine inhibits apoptosis
+*Conclusion: "Taken together, we demonstrated that nicotine inhibits apoptosis and proliferation by modulating AMPK/mTOR pathway-mediated autophagy and improves colitis severity in the DSS-induced UC mouse model. These findings provide new insights into the mechanism of nicotine treatment on UC autophagy. Further exploration of the mechanism of nicotine in autophagy and targeting factors might be considered a new approach for ulcerative colitis treatment."
-and proliferation by modulating AMPK/mTOR pathway-mediated autophagy and improves colitis severity in the DSS-induced UC mouse
-model. These findings provide new insights into the mechanism of nicotine treatment on UC-autophagy. Further exploration of the mechanism of nicotine in autophagy and targeting factors might be considered a new approach for ulcerative colitis treatment."
 *[https://sci-hub.st/10.1016/j.cbi.2020.108943 PDF Full paper]
 **Citation: Gao Q, Bi P, Luo D, Guan Y, Zeng W, Xiang H, Mi Q, Yang G, Li X, Yang B. Nicotine-induced autophagy via AMPK/mTOR pathway exerts protective effect in colitis mouse model. Chem Biol Interact. 2020 Feb 1;317:108943. doi: 10.1016/j.cbi.2020.108943. Epub 2020 Jan 10. PMID: 31926917.