Nicotine therapeutic benefits: Difference between revisions

Nicotine suppresses hyperexcitability of colonic sensory neurons and visceral hypersensivity in mouse model of colonic inflammation
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**Citation: AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. J Pharmacol Exp Ther. 2013 Jan;344(1):207-17. doi: 10.1124/jpet.112.198796. Epub 2012 Oct 31. PMID: 23115221; PMCID: PMC3533410.
**Citation: AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. J Pharmacol Exp Ther. 2013 Jan;344(1):207-17. doi: 10.1124/jpet.112.198796. Epub 2012 Oct 31. PMID: 23115221; PMCID: PMC3533410.
***Acknowledgement: This work was supported by National Institutes of Health [Grants DA-019377; (to M.I.D.) and DK 046367] (to H.I.A.).
***Acknowledgement: This work was supported by National Institutes of Health [Grants DA-019377; (to M.I.D.) and DK 046367] (to H.I.A.).
===2012 [https://journals.physiology.org/doi/full/10.1152/ajpgi.00411.2011 Nicotine suppresses hyperexcitability of colonic sensory neurons and visceral hypersensivity in mouse model of colonic inflammation]===
*Animal study
*"In summary, in an acute and postinflammatory model of colitis, we demonstrated that nAChRs mediate suppression of hyperexcitability of colonic sensory. The present study also highlights the potential of in vivo treatment with nicotine towards its antinociceptive effects in colonic inflammation."
**Citation: Abdrakhmanova GR, Kang M, Imad Damaj M, Akbarali HI. Nicotine suppresses hyperexcitability of colonic sensory neurons and visceral hypersensivity in mouse model of colonic inflammation. Am J Physiol Gastrointest Liver Physiol. 2012 Apr;302(7):G740-7. doi: 10.1152/ajpgi.00411.2011. Epub 2012 Jan 12. PMID: 22241859; PMCID: PMC3330777."
***Acknowledgement: This work was supported by the National Institute of Diabetes and Digestive and Kidney Diseases Grant DK-046367 (to H. I. Akbarali).


===2011 [https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-129 Anti-inflammatory effects of nicotine in obesity and ulcerative colitis]===
===2011 [https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-129 Anti-inflammatory effects of nicotine in obesity and ulcerative colitis]===