Nicotine therapeutic benefits: Difference between revisions

Line 677:

*Despite the completely destructive and harmful effects of cigarette smoke, nicotine via stimulation of the α7 receptor can promote the anti-inflammatory benefits on the immune system. However, these effects depend on the concentration, and administration methods are different and sometimes contradictory. It can be used successfully to treat or inhibit autoimmune diseases. Although the exact mechanism of this treatment is unknown, it appears to involve inhibiting downstream intracellular pathways that lead to the secretion of pre-inflammatory cytokines.

**Citation: Mahmoudzadeh L, Abtahi Froushani SM, Ajami M, Mahmoudzadeh M. Effect of Nicotine on Immune System Function. Adv Pharm Bull. 2023 Jan;13(1):69-78. doi: 10.34172/apb.2023.008. Epub 2022 Jan 4. PMID: 36721811; PMCID: PMC9871277.

===2023: [https://onlinelibrary.wiley.com/doi/10.1111/acer.15103 Inflammatory cytokines in alcohol use disorder patients are lower in smokers and users of smokeless tobacco]===

*Our findings may indicate that nicotine has anti-inflammatory effects in patients with AUD.

**Citation: Bolstad I, Lien L, Moe JS, Pandey S, Toft H, Bramness JG. Inflammatory cytokines in alcohol use disorder patients are lower in smokers and users of smokeless tobacco. Alcohol Clin Exp Res (Hoboken). 2023 Jul;47(7):1352-1363. doi: 10.1111/acer.15103. Epub 2023 May 30. PMID: 37208927.

***Acknowledgement: This work was financially supported by The Research Council of Norway, grant FRIPRO 251140.

===2022 [https://www.frontiersin.org/articles/10.3389/fimmu.2022.826889/full Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects]===

@@ Line 677: / Line 677: @@
 *Despite the completely destructive and harmful effects of cigarette smoke, nicotine via stimulation of the α7 receptor can promote the anti-inflammatory benefits on the immune system. However, these effects depend on the concentration, and administration methods are different and sometimes contradictory. It can be used successfully to treat or inhibit autoimmune diseases. Although the exact mechanism of this treatment is unknown, it appears to involve inhibiting downstream intracellular pathways that lead to the secretion of pre-inflammatory cytokines.
 **Citation: Mahmoudzadeh L, Abtahi Froushani SM, Ajami M, Mahmoudzadeh M. Effect of Nicotine on Immune System Function. Adv Pharm Bull. 2023 Jan;13(1):69-78. doi: 10.34172/apb.2023.008. Epub 2022 Jan 4. PMID: 36721811; PMCID: PMC9871277.
+===2023: [https://onlinelibrary.wiley.com/doi/10.1111/acer.15103 Inflammatory cytokines in alcohol use disorder patients are lower in smokers and users of smokeless tobacco]===
+*Our findings may indicate that nicotine has anti-inflammatory effects in patients with AUD.
+**Citation: Bolstad I, Lien L, Moe JS, Pandey S, Toft H, Bramness JG. Inflammatory cytokines in alcohol use disorder patients are lower in smokers and users of smokeless tobacco. Alcohol Clin Exp Res (Hoboken). 2023 Jul;47(7):1352-1363. doi: 10.1111/acer.15103. Epub 2023 May 30. PMID: 37208927.
+***Acknowledgement: This work was financially supported by The Research Council of Norway, grant FRIPRO 251140.
 ===2022 [https://www.frontiersin.org/articles/10.3389/fimmu.2022.826889/full Nicotine in Inflammatory Diseases: Anti-Inflammatory and Pro-Inflammatory Effects]===