Nicotine therapeutic benefits: Difference between revisions
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*Results of this study show that nicotine reduces the alveolar inflammatory response to S. rectivirgula antigen and affects some AM (stimulated with LPS or S. rectivirgula) functions in vitro. This influence could be, at least in part, responsible for the protection that smokers have against development of HP. Because nicotine is effective in the treatment of ulcerative colitis, it could also be of interest in the treatment of HP and other pulmonary inflammatory diseases. | *Results of this study show that nicotine reduces the alveolar inflammatory response to S. rectivirgula antigen and affects some AM (stimulated with LPS or S. rectivirgula) functions in vitro. This influence could be, at least in part, responsible for the protection that smokers have against development of HP. Because nicotine is effective in the treatment of ulcerative colitis, it could also be of interest in the treatment of HP and other pulmonary inflammatory diseases. | ||
**Citation: Blanchet MR, Israël-Assayag E, Cormier Y. Inhibitory effect of nicotine on experimental hypersensitivity pneumonitis in vivo and in vitro. Am J Respir Crit Care Med. 2004 Apr 15;169(8):903-9. doi: 10.1164/rccm.200210-1154OC. Epub 2003 Dec 30. PMID: 14701707. | **Citation: Blanchet MR, Israël-Assayag E, Cormier Y. Inhibitory effect of nicotine on experimental hypersensitivity pneumonitis in vivo and in vitro. Am J Respir Crit Care Med. 2004 Apr 15;169(8):903-9. doi: 10.1164/rccm.200210-1154OC. Epub 2003 Dec 30. PMID: 14701707. | ||
===1987: [https://pubmed.ncbi.nlm.nih.gov/3499342/ Prevalence and incidence of chronic bronchitis and farmer's lung with respect to age, sex, atopy, and smoking]=== | |||
*Farmer's lung was only slightly more common among atopic than among non-atopic subjects and twice as common among non-smokers as among smokers. | |||
**Citation: Terho EO, Husman K, Vohlonen I. Prevalence and incidence of chronic bronchitis and farmer's lung with respect to age, sex, atopy, and smoking. Eur J Respir Dis Suppl. 1987;152:19-28. PMID: 3499342. | |||
===1977: [https://pmc.ncbi.nlm.nih.gov/articles/PMC470791/ Extrinsic allergic alveolitis: a disease commoner in non-smokers.]=== | ===1977: [https://pmc.ncbi.nlm.nih.gov/articles/PMC470791/ Extrinsic allergic alveolitis: a disease commoner in non-smokers.]=== |