Nicotine therapeutic benefits: Difference between revisions
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='''Pain / Analgesic'''= | ='''Pain / Analgesic'''= | ||
===2024: [https://pubmed.ncbi.nlm.nih.gov/39719676/ Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-blind Randomized Controlled Trial]=== | |||
*Postoperative pain scores at rest and on movement were lower in the nicotine group than in the placebo group at 6 hours, 12 hours, and 24 hours after surgery (P<0.05). Postoperative morphine consumption was lower in the nicotine group than in the placebo group (9.92 ± 4.0 vs. 15.9 ± 5.0 mg, respectively; P=0.0002). | |||
**Citation: Maheshwari A, Gupta M, Garg B, Singh AK, Khanna P. Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-blind Randomized Controlled Trial. J Neurosurg Anesthesiol. 2024 Dec 25. doi: 10.1097/ANA.0000000000001022. Epub ahead of print. PMID: 39719676. | |||
***Acknowledgement: Paywalled, can not access | |||
===2023: [https://pubmed.ncbi.nlm.nih.gov/37132069/ Effect of perioperative high-dose transdermal nicotine patch on pain sensitivity among male abstinent tobacco smokers undergoing abdominal surgery: A randomized controlled pilot study]=== | ===2023: [https://pubmed.ncbi.nlm.nih.gov/37132069/ Effect of perioperative high-dose transdermal nicotine patch on pain sensitivity among male abstinent tobacco smokers undergoing abdominal surgery: A randomized controlled pilot study]=== | ||
*Perioperative high-dose nicotine replacement therapy may help to relieve postoperative pain among male smoking-abstinent patients undergoing abdominal surgery. | *Perioperative high-dose nicotine replacement therapy may help to relieve postoperative pain among male smoking-abstinent patients undergoing abdominal surgery. | ||