Nicotine therapeutic benefits: Difference between revisions
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(→Mental Health - ADD/ADHD: 1998 Transdermal nicotine effects on attention) |
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==Mental Health - ADD/ADHD== | ==Mental Health - ADD / ADHD / Attention== | ||
*[https://www.nami.org/About-Mental-Illness/Mental-Health-Conditions/ADHD Attention Deficit Hyperactivity Disorder (ADHD) - Information from NAMI] | *[https://www.nami.org/About-Mental-Illness/Mental-Health-Conditions/ADHD Attention Deficit Hyperactivity Disorder (ADHD) - Information from NAMI] | ||
*[https://www.understood.org/en/learning-thinking-differences/child-learning-disabilities/add-adhd/is-adhd-a-mental-illness Is ADHD a mental illness?] | *[https://www.understood.org/en/learning-thinking-differences/child-learning-disabilities/add-adhd/is-adhd-a-mental-illness Is ADHD a mental illness?] | ||
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*Citation: Alexandra S. Potter, Paul A. Newhouse, Acute nicotine improves cognitive deficits in young adults with attention-deficit/hyperactivity disorder, Pharmacology Biochemistry and Behavior, Volume 88, Issue 4, 2008, Pages 407-417, ISSN 0091-3057, doi: 10.1016/j.pbb.2007.09.014. | *Citation: Alexandra S. Potter, Paul A. Newhouse, Acute nicotine improves cognitive deficits in young adults with attention-deficit/hyperactivity disorder, Pharmacology Biochemistry and Behavior, Volume 88, Issue 4, 2008, Pages 407-417, ISSN 0091-3057, doi: 10.1016/j.pbb.2007.09.014. | ||
*Acknowledgements: This work was supported by: GCRC M01-00109 and Targacept Inc. | *Acknowledgements: This work was supported by: GCRC M01-00109 and Targacept Inc. | ||
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*[https://sci-hub.st/https://doi.org/10.1016/j.physbeh.2005.12.011 PDF Version] | *[https://sci-hub.st/https://doi.org/10.1016/j.physbeh.2005.12.011 PDF Version] | ||
*Citation: D.V. Poltavski, T. Petros, Effects of transdermal nicotine on attention in adult non-smokers with and without attentional deficits, Physiology & Behavior, Volume 87, Issue 3, 2006, Pages 614-624, ISSN 0031-9384, doi: 10.1016/j.physbeh.2005.12.011. | *Citation: D.V. Poltavski, T. Petros, Effects of transdermal nicotine on attention in adult non-smokers with and without attentional deficits, Physiology & Behavior, Volume 87, Issue 3, 2006, Pages 614-624, ISSN 0031-9384, doi: 10.1016/j.physbeh.2005.12.011. | ||
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===1998 [https://pubmed.ncbi.nlm.nih.gov/9860103/ Transdermal nicotine effects on attention]=== | |||
*This study shows that, in addition to reducing attentional impairment, nicotine administered via transdermal patches can improve attentiveness in normal adult non-smokers. | |||
*[https://sci-hub.st/10.1007/s002130050750 PDF Version] | |||
*Citation: Levin ED, Conners CK, Silva D, Hinton SC, Meck WH, March J, Rose JE. Transdermal nicotine effects on attention. Psychopharmacology (Berl). 1998 Nov;140(2):135-41. doi: 10.1007/s002130050750. PMID: 9860103 | |||
*Acknowledgement: The authors thank R.J. Reynolds for financial support of the project. Work on this article was partially supported by Career Science Award (K05MH0122903) to Dr. Conners and Research Scientist Development Award (K02MH0098102) to Dr. March | |||
===1996 [https://pubmed.ncbi.nlm.nih.gov/8741955/ Nicotine effects on adults with attention-deficit/hyperactivity disorder]=== | ===1996 [https://pubmed.ncbi.nlm.nih.gov/8741955/ Nicotine effects on adults with attention-deficit/hyperactivity disorder]=== | ||
*Nicotine caused a significant overall nicotine-induced improvement on the CGI. This effect was significant when only the nonsmokers were considered, which indicated that it was not due merely to withdrawal relief. Nicotine caused significantly increased vigor as measured by the POMS test. Nicotine caused an overall significant reduction in reaction time (RT) on the CPT, as well as, with the smokers, a significant reduction in another index of inattention, variability in reaction time over trial blocks. Nicotine improved accuracy of time estimation and lowered variability of time-estimation response curves. Because improvements occurred among nonsmokers, the nicotine effect appears not to be merely a relief of withdrawal symptoms. It is concluded that nicotine deserves further clinical trials with ADHD. | *Nicotine caused a significant overall nicotine-induced improvement on the CGI. This effect was significant when only the nonsmokers were considered, which indicated that it was not due merely to withdrawal relief. Nicotine caused significantly increased vigor as measured by the POMS test. Nicotine caused an overall significant reduction in reaction time (RT) on the CPT, as well as, with the smokers, a significant reduction in another index of inattention, variability in reaction time over trial blocks. Nicotine improved accuracy of time estimation and lowered variability of time-estimation response curves. Because improvements occurred among nonsmokers, the nicotine effect appears not to be merely a relief of withdrawal symptoms. It is concluded that nicotine deserves further clinical trials with ADHD. | ||
*[https://sci-hub.st/10.1007/BF02246281 PDF Version] | |||
*Citation: Levin ED, Conners CK, Sparrow E, Hinton SC, Erhardt D, Meck WH, Rose JE, March J. Nicotine effects on adults with attention-deficit/hyperactivity disorder. Psychopharmacology (Berl). 1996 Jan;123(1):55-63. doi: 10.1007/BF02246281. PMID: 8741955. | |||
*Acknowledgement: The authors thank Dr. Allen Frances, Chairman of the Department of Psychiatry, Duke University Meidcal Center for his finanical support of the project. Work on this article was partially supported by Career Science Award (K05MH01229-03) to Dr. Conners and Research Scientist Development Award (K20MH00981-02) to Dr. March and a Young Investigator Award from the National Alliance for Research Schizophenia and Depression to Dr. Levin. | |||
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