Does nicotine damage the developing adolescent brain?: Difference between revisions
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*"Animal model studies have found that nicotine can affect maturation of brain parts associated with executive function and decision-making, potentially leading to more impulsive behavior, cognitive deficits, and greater likelihood to self-administer other drugs. In addition, there is evidence in humans of neurological changes attributed to nicotine in the brains of adolescent smokers, interpreted by some as reflecting similar harmful effects to those in the animal models." | *"Animal model studies have found that nicotine can affect maturation of brain parts associated with executive function and decision-making, potentially leading to more impulsive behavior, cognitive deficits, and greater likelihood to self-administer other drugs. In addition, there is evidence in humans of neurological changes attributed to nicotine in the brains of adolescent smokers, interpreted by some as reflecting similar harmful effects to those in the animal models." | ||
*"These studies lead some researchers to suspect that adolescent nicotine use in any form may lead to long-term structural and functional brain changes with associated negative implications for cognition or impulse control. However, given species differences and questions about the relevance of experimental animal nicotine dosing paradigms to human use patterns, the validity of extrapolation to humans is speculative. Whether impaired brain development with behavioral consequences occurs in young nicotine consumers is difficult to determine because of potential confounding of genetic and socioeconomic factors, the influence of other substance abuse, and the role of preexisting neuropsychiatric problems associated with youth smoking. Research has yet to isolate nicotine use in the adolescent years and then examine later sequelae. Still, concerns about brain function effects of nicotine exposure through vaping deserve serious examination." | *"These studies lead some researchers to suspect that adolescent nicotine use in any form may lead to long-term structural and functional brain changes with associated negative implications for cognition or impulse control. However, given species differences and questions about the relevance of experimental animal nicotine dosing paradigms to human use patterns, the validity of extrapolation to humans is speculative. Whether impaired brain development with behavioral consequences occurs in young nicotine consumers is difficult to determine because of potential confounding of genetic and socioeconomic factors, the influence of other substance abuse, and the role of preexisting neuropsychiatric problems associated with youth smoking. Research has yet to isolate nicotine use in the adolescent years and then examine later sequelae. Still, concerns about brain function effects of nicotine exposure through vaping deserve serious examination." | ||
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==2020: Dr. Brad Rodu== | |||
*[https://rodutobaccotruth.blogspot.com/2020/09/the-cdc-nicotine-brain-fallacy.html Source: The CDC Nicotine Brain Fallacy] / [https://louisville.edu/medicine/cancer-research/bkrodu01 Bio] | |||
*"The harm in brain development federal officials talk non-stop about only happens in laboratory torture of mice. Mouse studies are well known to be of questionable value in predicting human effects. There is absolutely no scientific evidence to support the claim that nicotine causes harm to human brain development, so it is astounding that federal officials traffic in this false narrative. This nonsense is an affront to 34 million adult current smokers and 55 million former smokers in the U.S., virtually all of whom started when they were teenagers. There is no evidence that their brain development was harmed, a fact that was specifically acknowledged by a prestigious nicotine researcher Dr. Neal Benowitz at an international tobacco meeting this week." | |||
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