VLN Cigarette: Difference between revisions

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== Studies ==
== Studies ==
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2771865


*"Is this strong policy statement warranted by the findings in this study? We think not. The main finding—a modest within-trial reduction in cigarette consumption—does not support the objectives of the comprehensive plan for nicotine regulation at a national level. The ability of the VLNC intervention to promote smoking cessation was specifically tested at week 12 when participants were offered $100 to abstain from smoking for 24 hours, a modest goal given that most smokers who abstain for 24 hours relapse, and smokers do not get such offers in real life. The VLNC intervention did not result in smoking cessation. This raises serious questions about the conclusion that a VLNC cigarette policy alone would promote smoking cessation or reduce morbidity and mortality. The health benefits of VLNC cigarettes remain unclear. Reductions in the level of NNAL (4-[methylnitrosamino]-1-[3-pyridyl]-1-butanol), a biomarker for tobacco smoke carcinogens, were small, and 1 group (opioid users) experienced an increase in the level of NNAL."


Very-Low Nicotine Cigarettes and Non-Daily Smokers https://clinicaltrials.gov/ct2/show/NCT02228824
Very-Low Nicotine Cigarettes and Non-Daily Smokers https://clinicaltrials.gov/ct2/show/NCT02228824