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*Citation: Guslandi M. Nicotine treatment for ulcerative colitis. Br J Clin Pharmacol. 1999 Oct;48(4):481-4. doi: 10.1046/j.1365-2125.1999.00039.x. PMID: 10583016; PMCID: PMC2014383. | *Citation: Guslandi M. Nicotine treatment for ulcerative colitis. Br J Clin Pharmacol. 1999 Oct;48(4):481-4. doi: 10.1046/j.1365-2125.1999.00039.x. PMID: 10583016; PMCID: PMC2014383. | ||
*Keywords: enemas, nicotine, transdermal patches, ulcerative colitis | *Keywords: enemas, nicotine, transdermal patches, ulcerative colitis | ||
===1996 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398677/ The role of cigarettes and nicotine in the onset and treatment of ulcerative colitis.]=== | |||
*Nicotine is believed to be the pharmacological ingredient of tobacco that is responsible for this beneficial deterrent of UC and several clinical trials using nicotine have demonstrated it to be an effective therapeutic agent in the treatment of ulcerative colitis. Although the aetiology of ulcerative colitis is unclear, current research using nicotine-based products has produced some interesting clues, together with the possibility of some form of therapeutic treatment based on nicotine administration. | |||
*[https://sci-hub.st/10.1136/pgmj.72.854.714 PDF Version] | |||
*Citation: Birtwistle J. The role of cigarettes and nicotine in the onset and treatment of ulcerative colitis. Postgrad Med J. 1996 Dec;72(854):714-8. doi: 10.1136/pgmj.72.854.714. PMID: 9015463; PMCID: PMC2398677. | |||
===1996 [https://pubmed.ncbi.nlm.nih.gov/9006184/ Does nicotine have beneficial effects in the treatment of certain diseases?]=== | |||
*Nicotine may have therapeutic uses in the treatment of ulcerative colitis. | |||
*Drug companies have often refused to fund legitimate and valid research into the potential therapeutic use of nicotine owing to its association with smoking and its image of an abusable drug. Many in the health profession fail to acknowledge the evidence which suggests that nicotine may have potential therapeutic value. | |||
*[https://sci-hub.st/10.12968/bjon.1996.5.19.1195 PDF Version] | |||
*Citation: Birtwistle J, Hall K. Does nicotine have beneficial effects in the treatment of certain diseases? Br J Nurs. 1996 Oct 24-Nov 13;5(19):1195-202. doi: 10.12968/bjon.1996.5.19.1195. PMID: 9006184. | |||
===1991 [https://pubmed.ncbi.nlm.nih.gov/1859921/ Beneficial effects of nicotine]=== | |||
*When chronically taken, nicotine may result in: protection against ulcerative colitis (other diseases mentioned in study) | |||
*[https://sci-hub.st/10.1111/j.1360-0443.1991.tb01810.x PDF Version] | |||
*Citation: Jarvik ME. Beneficial effects of nicotine. Br J Addict. 1991 May;86(5):571-5. doi: 10.1111/j.1360-0443.1991.tb01810.x. PMID: 1859921. | |||
*Acknowledgement: Supported by U. C. Tobacco-related Disease program, grant # RT87 and a grant from the John D. and Catherine T. MacArthur Foundation. | |||
==Downs Syndrome== | ==Downs Syndrome== | ||
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