Nicotine therapeutic benefits: Difference between revisions
Attenuation of collagen induced arthritis via suppression on Th17 response by activating cholinergic anti-inflammatory pathway with nicotine |
Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration |
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='''Arthritis/Skeletal'''= | ='''Arthritis/Skeletal'''= | ||
===2016 [https://www.spandidos-publications.com/mmr/14/6/5057 Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration]=== | |||
*Animal study | |||
*Taken together, the present results indicated that nicotine‑induced activation of the CAP in mice with CIA may reduce the number of macrophages in the synovium, which may serve a role in alleviating arthritis in mice. | |||
**Citation: Li S, Zhou B, Liu B, Zhou Y, Zhang H, Li T, Zuo X. Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration. Mol Med Rep. 2016 Dec;14(6):5057-5064. doi: 10.3892/mmr.2016.5904. Epub 2016 Oct 31. PMID: 27840928; PMCID: PMC5355730. | |||
***Acknowledgement: The present study was supported by a grant from the National Natural Science Foundation of China (grant no. 81571602). | |||
===2014 [https://pubmed.ncbi.nlm.nih.gov/24313917/ Regulatory effect of nicotine on collagen-induced arthritis and on the induction and function of in vitro-cultured Th17 cells]=== | ===2014 [https://pubmed.ncbi.nlm.nih.gov/24313917/ Regulatory effect of nicotine on collagen-induced arthritis and on the induction and function of in vitro-cultured Th17 cells]=== | ||
*Animal Study | *Animal Study | ||