Nicotine therapeutic benefits: Difference between revisions

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***Acknowledgement: Supported in part by: NIH/NIAAA R03 AA022479 and NIH/NIGMS (2 SO6 GM08016‐39) (YT), and NIEHS R01ES10563 and R01ES07331 (MA).
***Acknowledgement: Supported in part by: NIH/NIAAA R03 AA022479 and NIH/NIGMS (2 SO6 GM08016‐39) (YT), and NIEHS R01ES10563 and R01ES07331 (MA).


=== 2020: [https://n.neurology.org/content/94/20/e2132 Tobacco smoking and the risk of Parkinson disease A 65-year follow-up of 30,000 male British doctors] ===
=== 2020: [https://n.neurology.org/content/94/20/e2132 Tobacco smoking and the risk of Parkinson disease A 65-year follow-up of 30,000 male British doctors] ===  
 
*In contrast to previous suggestions, the present report demonstrates a causally protective effect of current smoking on the risk of PD, which may provide insights into the etiology of PD.
* While many reports suggest causality, and often this is a stretch at best, here the authors discuss what is needed to prove a causal relationship and satisfy those requirements.
**Citation: Mappin-Kasirer B, Pan H, Lewington S, Kizza J, Gray R, Clarke R, Peto R. Tobacco smoking and the risk of Parkinson disease: A 65-year follow-up of 30,000 male British doctors. Neurology. 2020 May 19;94(20):e2132-e2138. doi: 10.1212/WNL.0000000000009437. Epub 2020 May 5. PMID: 32371450; PMCID: PMC7526668.
* It is a rare example of how you should approach causality, reading the text gives a clear account of the criteria the authors consider to prove causality, and how these are met.
* In contrast to previous suggestions, the present report demonstrates a causally protective effect of current smoking on the risk of PD, which may provide insights into the etiology of PD.
* Benjamin Mappin-Kasirer, Hongchao Pan, Sarah Lewington, Jennifer Kizza, Richard Gray, Robert Clarke, Richard Peto First published May 5, 2020, DOI: <nowiki>https://doi.org/10.1212/WNL.0000000000009437</nowiki>


===2020 [https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqaa186/5876214?redirectedFrom=fulltext Dietary nicotine intake and risk of Parkinson disease: a prospective study]===  
===2020 [https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqaa186/5876214?redirectedFrom=fulltext Dietary nicotine intake and risk of Parkinson disease: a prospective study]===