Nicotine therapeutic benefits: Difference between revisions

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*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018192/pdf/CN-16-403.pdf PDF Version]

*Citation: Valentine G, Sofuoglu M. Cognitive Effects of Nicotine: Recent Progress. Curr Neuropharmacol. 2018;16(4):403-414. doi: 10.2174/1570159X15666171103152136. PMID: 29110618; PMCID: PMC6018192.

===2017: [https://www.nature.com/articles/npp201715 Repeated Nicotine Strengthens Gamma Oscillations in the Prefrontal Cortex and Improves Visual Attention]===

*Consistent with this mechanism, the repeat dosing regimen in a separate cohort of subjects led to improved performance in an attention task. These data suggest that procognitive effects of nicotine may involve development of enhanced gamma oscillatory activity and a shift to excitatory–inhibitory balance in PFC neural activity. In the context of the clinical use of nicotine and related agonists for treating cognitive deficits, these data suggest that daily dosing may be critical to allow for development of robust gamma oscillations.

**Citation: Bueno-Junior, L., Simon, N., Wegener, M. et al. Repeated Nicotine Strengthens Gamma Oscillations in the Prefrontal Cortex and Improves Visual Attention. Neuropsychopharmacol 42, 1590–1598 (2017). https://doi.org/10.1038/npp.2017.15

***Acknowledgement: This work was supported by São Paulo Research Foundation, Brazil (FAPESP; fellowships 2012/21387-8 and 2012/06123-4) for investigator LSBJ, R01MH084906 (BM), and a pilot fund from the Center for Evaluation of Nicotine in Cigarettes (NWS). The authors declare no conflict of interest.

===2016: [https://truthinitiative.org/sites/default/files/media/files/2019/08/ReThinking-Nicotine_0.pdf Re-thinking nicotine and its effects]===

@@ Line 576: / Line 576: @@
 *[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018192/pdf/CN-16-403.pdf PDF Version]
 *Citation: Valentine G, Sofuoglu M. Cognitive Effects of Nicotine: Recent Progress. Curr Neuropharmacol. 2018;16(4):403-414. doi: 10.2174/1570159X15666171103152136. PMID: 29110618; PMCID: PMC6018192.
+===2017: [https://www.nature.com/articles/npp201715 Repeated Nicotine Strengthens Gamma Oscillations in the Prefrontal Cortex and Improves Visual Attention]===
+*Consistent with this mechanism, the repeat dosing regimen in a separate cohort of subjects led to improved performance in an attention task. These data suggest that procognitive effects of nicotine may involve development of enhanced gamma oscillatory activity and a shift to excitatory–inhibitory balance in PFC neural activity. In the context of the clinical use of nicotine and related agonists for treating cognitive deficits, these data suggest that daily dosing may be critical to allow for development of robust gamma oscillations.
+**Citation: Bueno-Junior, L., Simon, N., Wegener, M. et al. Repeated Nicotine Strengthens Gamma Oscillations in the Prefrontal Cortex and Improves Visual Attention. Neuropsychopharmacol 42, 1590–1598 (2017). https://doi.org/10.1038/npp.2017.15
+***Acknowledgement: This work was supported by São Paulo Research Foundation, Brazil (FAPESP; fellowships 2012/21387-8 and 2012/06123-4) for investigator LSBJ, R01MH084906 (BM), and a pilot fund from the Center for Evaluation of Nicotine in Cigarettes (NWS). The authors declare no conflict of interest.
 ===2016: [https://truthinitiative.org/sites/default/files/media/files/2019/08/ReThinking-Nicotine_0.pdf Re-thinking nicotine and its effects]===