(Added section Abuse Liability - All THR Products) |
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*She says "honey, you need to get with the program, we were too poor when I was a kid to afford cotton candy, so now I'm having it whenever I want and any way I want it. Now give me the sweetest thing you got and I want cotton candy the next time I come here." | *She says "honey, you need to get with the program, we were too poor when I was a kid to afford cotton candy, so now I'm having it whenever I want and any way I want it. Now give me the sweetest thing you got and I want cotton candy the next time I come here." | ||
*"Ma'am, if you don't mind me asking, how old are you?". She looks at me and says "82, I quit smoking 6 months ago and now I'm going to live to be 102." | *"Ma'am, if you don't mind me asking, how old are you?". She looks at me and says "82, I quit smoking 6 months ago and now I'm going to live to be 102." | ||
=Abuse Liability - All THR Products= | |||
===2002: [https://pubmed.ncbi.nlm.nih.gov/12175452/ Flavor improvement does not increase abuse liability of nicotine chewing gum]=== | |||
*Improved flavor of nicotine gum does not increase abuse liability, but may be associated with enhanced craving reduction. | |||
*mint-flavored nicotine gum was rated as more palatable than the original nicotine gum, but the improvement in flavor did not increase abuse liability in adults (22 – 50 years old) or young adults (18 –21 years old). Since the aversive taste of the original nicotine gum was an important impediment to compliance (Rose, 1996) and treatment initiation, the availability of nicotine gum in different flavors and the development of alternative oral nicotine replacement products with appealing flavors may improve compliance and expand the range of options for those attempting to quit smoking, without posing an increased risk of abuse. | |||
*[https://sci-hub.se/10.1016/s0091-3057(02)00723-2 PDF Version] | |||
*Citation: Houtsmuller, E. J., Fant, R. V., Eissenberg, T. E., Henningfield, J. E., & Stitzer, M. L. (2002). Flavor improvement does not increase abuse liability of nicotine chewing gum. Pharmacology Biochemistry and Behavior, 72(3), 559–568. doi:10.1016/s0091-3057(02)00723-2 | |||
*Acknowledgement: This study was supported by SmithKline Beecham Consumer Healthcare. | |||
=Public Health Advantages / Concerns of Public Health Harms= | =Public Health Advantages / Concerns of Public Health Harms= | ||
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