Smokeless Tobacco - Pouches (not snus)

This page is for referencing the possible benefits of Smokeless tobacco - Pouches (not Snus) products vs. smoking cigarettes.

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Studies, Surveys, Papers

2020: Pharmacokinetic Comparison of a Novel Non-tobacco-Based Nicotine Pouch (ZYN) With Conventional, Tobacco-Based Swedish Snus and American Moist Snuff

• The two higher doses of ZYN (6 and 8 mg) deliver nicotine as quickly and to a similar extent as existing smokeless products, with no significant adverse effects.
• Citation: Lunell E, Fagerström K, Hughes J, Pendrill R. Pharmacokinetic Comparison of a Novel Non-tobacco-Based Nicotine Pouch (ZYN) With Conventional, Tobacco-Based Swedish Snus and American Moist Snuff. Nicotine Tob Res. 2020 Oct 8;22(10):1757-1763. doi: 10.1093/ntr/ntaa068. PMID: 32319528.

2020: An approach for the extract generation and toxicological assessment of tobacco-free ‘modern’ oral nicotine pouches

• This study demonstrates that tobacco-free nicotine pouches are significantly less biologically active than an equivalent reference Swedish-style snus product. Future product usage studies, pharmacokinetics and clinical studies will provide further data to substantiate the reduced risk potential of tobacco-free modern oral nicotine pouches (MOP).
• Citation: Bishop E, East N, Bozhilova S, Santopietro S, Smart D, Taylor M, Meredith S, Baxter A, Breheny D, Thorne D, Gaca M, An approach for the extract generation and toxicological assessment of tobacco-free ‘modern’ oral nicotine pouches, Food and Chemical Toxicology, Volume 145, 2020, 111713, ISSN 0278-6915, doi.org/10.1016/j.fct.2020.111713.
• Acknowledgement: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: BAT funded the project and all authors were employees of BAT at the time of the study conduct. LYFT tobacco-free modern oral nicotine pouches are manufactured and supplied by BAT.

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