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Replica is the First interlaboratory study in the world to replicate and validate high-profile studies on the cytotoxicity and inflammation induced by cigarette smoke and aerosol from electronic nicotine delivery systems (ENDS).

The Replica project team, directed by Prof. Giovanni Li Volti uses the most advanced tools and techniques and the most reliable methodologies to provide to the public with up-to-date information on ENDS.

In recent years, there has been an advancement in technologies capable to simulate human smoking and recreating closer physiological conditions for in vitro studies of smoke and aerosol cell exposure.

Based on these advancements Replica team of scientists has decided to replicate, for the first year of the study, three published works from the Tobacco Industry focusing on toxicological assessment and inflammation.