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*Though they may not be as harmless as previously proposed, it seems likely that on the spectrum of tobacco products, ECs are less harmful than TCs, and there is increasing evidence that ECs may help promote TC cessation. As such, ECs may be helpful for risk reduction | *Though they may not be as harmless as previously proposed, it seems likely that on the spectrum of tobacco products, ECs are less harmful than TCs, and there is increasing evidence that ECs may help promote TC cessation. As such, ECs may be helpful for risk reduction | ||
===2017: A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration=== | ===2017: [https://www.sciencedirect.com/science/article/pii/S0378427417302266 A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration]=== | ||
Exposure to 3R4F extract (20h) induced concentration-dependent inhibition of endothelial cell migration, with complete inhibition at concentrations >20%. E-cigarette extracts did not inhibit migration, even at double the 3R4F extract nicotine concentration, allowing cells to migrate into the wounded area. Our data demonstrate that e-cigarettes do not induce the inhibition of endothelial cell migration in vitro when compared to 3R4F. | *Exposure to 3R4F extract (20h) induced concentration-dependent inhibition of endothelial cell migration, with complete inhibition at concentrations >20%. E-cigarette extracts did not inhibit migration, even at double the 3R4F extract nicotine concentration, allowing cells to migrate into the wounded area. Our data demonstrate that e-cigarettes do not induce the inhibition of endothelial cell migration in vitro when compared to 3R4F. | ||
2017: Electronic cigarette smoking increases of arterial stiffness and oxidative stress to a lesser extent than a single normal cigarette: an acute and chronic study | *Citation: Taylor M, Jaunky T, Hewitt K, Breheny D, Lowe F, Fearon IM, Gaca M. A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration. Toxicol Lett. 2017 Aug 5;277:123-128. doi: 10.1016/j.toxlet.2017.06.001. Epub 2017 Jun 26. PMID: 28658606. | ||
Electronic cigarette smoking causes a smaller increase of arterial stiffness and oxidative stress, compared to a single normal cigarette in an acute setting. Replacement of normal cigarettes by a moderate nicotine concentration electronic cigarette results in improved aortic elasticity and oxidative stress within 1 month. | *Acknowledgement: All experimental work was funded by Nicoventures Ltd., UK, a wholly-owned subsidiary of British American Tobacco Investments Ltd. All study products were provided by Nicoventures. | ||
===2017: [https://academic.oup.com/eurheartj/article/38/suppl_1/ehx493.P5166/4086509 Electronic cigarette smoking increases of arterial stiffness and oxidative stress to a lesser extent than a single normal cigarette: an acute and chronic study]=== | |||
*Electronic cigarette smoking causes a smaller increase of arterial stiffness and oxidative stress, compared to a single normal cigarette in an acute setting. Replacement of normal cigarettes by a moderate nicotine concentration electronic cigarette results in improved aortic elasticity and oxidative stress within 1 month. | |||
*Citation: I. Ikonomidis, D. Vlastos, G. Kostelli, K. Kourea, O. Kondylopoulou, S. Vlachos, D. Benas, M. Varoudi, G. Pavlidis, V. Dede, H. Triantafyllidi, I. Andreadou, J. Lekakis, P5166 Electronic cigarette smoking increases of arterial stifness and oxidative stress to a lesser extent than a single normal cigarette: an acute and chronic study, European Heart Journal, Volume 38, Issue suppl_1, August 2017, ehx493.P5166, https://doi.org/10.1093/eurheartj/ehx493.P5166 | |||
===2017: Press Release: [https://en.interfax.com.ua/news/press-release/437152.html?fbclid=IwAR0-rdzdMygGbwW9pGc01XdupspoEUhVclbAU_A223Q0Y6RjE1GXd73JAhI New Technologies for Health: electronic substitutions for smoking reduce harm (research)]=== | |||
*"Our 6-month study convincingly demonstrated an improvement in endothelial function and a reduction in the risk of cardiovascular disease in smokers when switching to the use of ENDS." | |||
===2016: Cigarette smoke but not electronic cigarette aerosol activates a stress response in human coronary artery endothelial cells in culture=== | ===2016: Cigarette smoke but not electronic cigarette aerosol activates a stress response in human coronary artery endothelial cells in culture=== | ||
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