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*The results showed high cytotoxicity, mutagenicity and genotoxicity induced by cigarette smoke, but slight or no cytotoxic, mutagenic and genotoxic effects induced by the e-cigarette aerosol. Although the two studies presented some methodological differences, the findings supported those previously presented by Rudd and colleagues. | *The results showed high cytotoxicity, mutagenicity and genotoxicity induced by cigarette smoke, but slight or no cytotoxic, mutagenic and genotoxic effects induced by the e-cigarette aerosol. Although the two studies presented some methodological differences, the findings supported those previously presented by Rudd and colleagues. | ||
*Emma, R., Fuochi, V., Distefano, A., Partsinevelos, K., Rust, S., Zadjali, F., Al Tobi, M., Zadjali, R., Alharthi, Z., Pulvirenti, R., Furneri, P. M., Polosa, R., Sun, A., Caruso, M., & Li Volti, G. (2023). Cytotoxicity, mutagenicity and genotoxicity of electronic cigarettes emission aerosols compared to cigarette smoke: The REPLICA project. Scientific Reports, 13(1), 1-12. https://doi.org/10.1038/s41598-023-44626-1 | *Emma, R., Fuochi, V., Distefano, A., Partsinevelos, K., Rust, S., Zadjali, F., Al Tobi, M., Zadjali, R., Alharthi, Z., Pulvirenti, R., Furneri, P. M., Polosa, R., Sun, A., Caruso, M., & Li Volti, G. (2023). Cytotoxicity, mutagenicity and genotoxicity of electronic cigarettes emission aerosols compared to cigarette smoke: The REPLICA project. Scientific Reports, 13(1), 1-12. https://doi.org/10.1038/s41598-023-44626-1 | ||
===2022: [https://pubmed.ncbi.nlm.nih.gov/35858275/ Increased Levels of the Acrolein Metabolite 3-Hydroxypropyl Mercapturic Acid in the Urine of e-Cigarette Users]=== | |||
*All analytes were significantly higher in cigarette smokers than in either e-cigarette users or nonsmokers. | |||
*Citation: Chen M, Carmella SG, Lindgren BR, Luo X, Ikuemonisan J, Niesen B, Thomson NM, Murphy SE, Hatsukami DK, Hecht SS. Increased Levels of the Acrolein Metabolite 3-Hydroxypropyl Mercapturic Acid in the Urine of e-Cigarette Users. Chem Res Toxicol. 2023 Apr 17;36(4):583-588. doi: 10.1021/acs.chemrestox.2c00145. Epub 2022 Jul 20. PMID: 35858275; PMCID: PMC9852357. | |||
===2022: [https://f1000research.com/articles/9-1225#f1 Nicotine products relative risk assessment: an updated systematic review and meta-analysis [version 2; peer review: 1 approved, 1 approved with reservations<nowiki>]</nowiki> Previously titled: Nicotine products relative risk assessment: a systematic review and meta-analysis]=== | ===2022: [https://f1000research.com/articles/9-1225#f1 Nicotine products relative risk assessment: an updated systematic review and meta-analysis [version 2; peer review: 1 approved, 1 approved with reservations<nowiki>]</nowiki> Previously titled: Nicotine products relative risk assessment: a systematic review and meta-analysis]=== | ||
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