ENDS Cessation: Difference between revisions
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Richardpruen (talk | contribs) (Removed double template) |
Richardpruen (talk | contribs) (→Sudies, Papers, Randomised Controlled Trials etc...: added paper on the use of patches with ends for smoking cessation, interestingly patches did not statistically reduce ENDS use.) |
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This is little studied, and the product was developed by ex-smokers as a commercial alternative to cigarettes, from almost the very start (2010 for sure) consumers insisted on an off ramp. From the early days the nicotine refills where available in a range of strengths, from 48mg/ml at the high end, to 0.3mg/ml as well as zero nicotine at the low. The general advice has always been, select a product that works to prevent relapse to smoking, and once dissociated from smoking taper the nicotine level down at a rate that works to prevent return to smoking, eventually, however long it takes for the individual reach zero nicotine, then stop using the product entirely. Some find they are unable to stop vaping entirely, even without nicotine at all, and if you would return to smoking in that case, it is better to vape when needed than to light a cigarette and start the journey again. | This is little studied, and the product was developed by ex-smokers as a commercial alternative to cigarettes, from almost the very start (2010 for sure) consumers insisted on an off ramp. From the early days the nicotine refills where available in a range of strengths, from 48mg/ml at the high end, to 0.3mg/ml as well as zero nicotine at the low. The general advice has always been, select a product that works to prevent relapse to smoking, and once dissociated from smoking taper the nicotine level down at a rate that works to prevent return to smoking, eventually, however long it takes for the individual reach zero nicotine, then stop using the product entirely. Some find they are unable to stop vaping entirely, even without nicotine at all, and if you would return to smoking in that case, it is better to vape when needed than to light a cigarette and start the journey again. | ||
=== Should it be the users choice | === Should it be the users choice to stop vaping, at their preferred pace? === | ||
==== Short answer: Yes! ==== | ==== Short answer: Yes! ==== | ||
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== Sudies, Papers, Randomised Controlled Trials etc... == | == Sudies, Papers, Randomised Controlled Trials etc... == | ||
=== 2023: [https://link.springer.com/article/10.1007/s00213-023-06401-y Smoking reduction using electronic nicotine delivery systems in combination with nicotine skin patches] === | |||
* Jed E. Rose, Suzanne Frisbee, David Campbell, Alfred Salley, Susan Claerhout & James M. Davis Psychopharmacology (2023) | |||
* Electronic nicotine delivery systems (ENDS) are used by smokers seeking to reduce combustible cigarette (CC) use, but the role of nicotine replacement vs. behavioral and sensory factors is still poorly understood. We hypothesized that providing nicotine from ENDS in addition to nicotine skin patches would promote smoking reduction relative to non-nicotine control ENDS. | |||
* The use of nicotine in ENDS led to significant reductions in smoking (ENDS nicotine vs. placebo difference in CO change = −9.2 ppm; 90% CI (−1.5 ppm, −16.9 ppm)) and was highly correlated with reductions in self-reported cigarettes per day (''r''=0.6). The effect of nicotine in nicotine patches was not statistically significant (patch nicotine vs. placebo difference in CO change = −0.1 ppm; 90% CI (−7.8 ppm, 7.6 ppm)). | |||
* The presence of nicotine in ENDS was associated with a large reduction in smoking. Additional studies will be needed to determine whether there may be additive effects of nicotine ENDS and nicotine patches on smoking abstinence. | |||
* Note: Some success has been had with NHS stop smoking services, particularly after the 20mg nicotine cap. It might be that if nicotine is restricted in ENDS then additional sources of nicotine become more important? (Sadly the NHS have not provided numbers yet, but we welcome more research and data. (ed.)) | |||
=== 2023: [https://link.springer.com/epdf/10.1186/s12916-023-02919-2 Varenicline and counseling for vaping cessation: a double‑blind, randomized, parallel‑group, placebo‑controlled trial] === | === 2023: [https://link.springer.com/epdf/10.1186/s12916-023-02919-2 Varenicline and counseling for vaping cessation: a double‑blind, randomized, parallel‑group, placebo‑controlled trial] === | ||