Nicotine therapeutic benefits: Difference between revisions

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(→‎Mental Health - Schizophrenia: Add study on nicotine and genetic role)
(→‎Autism: added mouse study on autism)
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* In multivariable analysis adjusted for age, 63 income, insurance type, race, sex, depression, and anxiety, only the associations with cannabis 64 (aOR 1.49, 95% CI 1.24-1.80), e-cigarette (aOR 0.71, 95% CI 0.65-0.77), and regular cigarette 65 use (aOR 0.65, 95% CI 0.63-0.68) persisted (Table I)
* In multivariable analysis adjusted for age, 63 income, insurance type, race, sex, depression, and anxiety, only the associations with cannabis 64 (aOR 1.49, 95% CI 1.24-1.80), e-cigarette (aOR 0.71, 95% CI 0.65-0.77), and regular cigarette 65 use (aOR 0.65, 95% CI 0.63-0.68) persisted (Table I)


='''Autism'''=  
='''Autism'''=
 
=== 2020: [https://pubmed.ncbi.nlm.nih.gov/32691528/ The Role of Nicotinic Receptors in the Attenuation of Autism-Related Behaviors in a Murine BTBR T + tf/J Autistic Model] ===
 
* Mouse study
* Autism Research 2020 Aug;13(8):1311-1334  doi: 10.1002/aur.2342. Epub 2020 Jul 21.
 
===2018 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394231/ An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder]===  
===2018 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394231/ An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder]===  
*Taken together, our study provides evidence for the feasibility and tolerability of [[Special:MyLanguage/Abbreviations|'''transdermal nicotine (TN/TNP)''']] in a small sample of adults with severe [[Special:MyLanguage/Abbreviations|'''Autism Spectrum Disorder (ASD)''']] symptoms and pathological chronic aggression and irritability.  
*Taken together, our study provides evidence for the feasibility and tolerability of [[Special:MyLanguage/Abbreviations|'''transdermal nicotine (TN/TNP)''']] in a small sample of adults with severe [[Special:MyLanguage/Abbreviations|'''Autism Spectrum Disorder (ASD)''']] symptoms and pathological chronic aggression and irritability.