Nicotine therapeutic benefits: Difference between revisions
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Richardpruen (talk | contribs) (Added 2 studies on Parkinson's disease) |
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* Mouse study | * Mouse study | ||
* Ruan S, Xie J, Wang L, Guo L, Li Y, Fan W, Ji R, Gong Z, Xu Y, Mao J, Xie J. Front Pharmacol. 2023 Feb 2;14:1088957. doi: 10.3389/fphar.2023.1088957. eCollection 2023. PMID: 36817162 Free PMC article. | * Ruan S, Xie J, Wang L, Guo L, Li Y, Fan W, Ji R, Gong Z, Xu Y, Mao J, Xie J. Front Pharmacol. 2023 Feb 2;14:1088957. doi: 10.3389/fphar.2023.1088957. eCollection 2023. PMID: 36817162 Free PMC article. | ||
=== 2023: [https://jamanetwork.com/journals/jamaneurology/article-abstract/2805037 Risk of Parkinson Disease Among Service Members at Marine Corps Base Camp Lejeune] === | |||
* You have to dig into text and tables to spot “Parkinson disease risk was substantially lower among Black veterans and EVER-SMOKERS (OR 0.49, 95% CI: 0.40-0.61). | |||
* That is a huge benefit that is seemingly not followed up, but probably should be. | |||
* Samuel M. Goldman, MD, MPH; Frances M. Weaver, PhD; Kevin T. Stroupe, PhD; et al JAMA Neurol. Published online May 15, 2023. doi:10.1001/jamaneurol.2023.1168 | |||
=== 2020: [https://n.neurology.org/content/94/20/e2132 Tobacco smoking and the risk of Parkinson disease A 65-year follow-up of 30,000 male British doctors] === | |||
* While many reports suggest causality, and often this is a stretch at best, here the authors discuss what is needed to prove a causal relationship and satisfy those requirements. | |||
* It is a rare example of how you should approach causality, reading the text gives a clear account of the criteria the authors consider to prove causality, and how these are met. | |||
* In contrast to previous suggestions, the present report demonstrates a causally protective effect of current smoking on the risk of PD, which may provide insights into the etiology of PD. | |||
* Benjamin Mappin-Kasirer, Hongchao Pan, Sarah Lewington, Jennifer Kizza, Richard Gray, Robert Clarke, Richard Peto First published May 5, 2020, DOI: <nowiki>https://doi.org/10.1212/WNL.0000000000009437</nowiki> | |||
===2020 [https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqaa186/5876214?redirectedFrom=fulltext Dietary nicotine intake and risk of Parkinson disease: a prospective study]=== <!--T:213--> | ===2020 [https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqaa186/5876214?redirectedFrom=fulltext Dietary nicotine intake and risk of Parkinson disease: a prospective study]=== <!--T:213--> |