Myth: Alternative nicotine products don't help people stop smoking: Difference between revisions

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=Shareables=
=Studies - No Intention of Quitting Smoking=


=Studies - Smoking Cessation=


===[https://docs.google.com/document/d/13-D2q1P0KpmZuoFBkKV4l9wUEQ-zcHfp6MAVJGoAaG4/edit?usp=sharing INNCO: Myth of the month: Ecigs and snus don’t help smokers quit]===
=== 2023: [https://pubmed.ncbi.nlm.nih.gov/37148992/ Efficacy and Safety of E-Cigarette Use for Smoking Cessation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.] ===
*Each statement on this doc complies with the character limits on twitter. Feel free to copy/paste them into tweets.
* Results: A total of 5 RCTs (n=3,253) were included. Compared with conventional smoking cessation therapies, the use of nicotine e-cigarettes was associated with an increase in abstinence, defined by the most rigorous criterion of abstinence reported (RR: 1.77; 95% CI: 1.29-2.44). Nicotine e-cigarettes also increased abstinence (defined by the most rigorous criterion) compared to non-nicotine e-cigarettes (RR: 1.56; 95% CI: 1.13-2.15). The incidence of death or SAEs was low across all trials at maximum follow-up.
* Conclusions: Among individuals attempting to quit smoking, nicotine e-cigarettes are more efficacious than conventional nicotine replacement or behavioral smoking cessation therapies and may prove beneficial in reducing smoking-related health risks.


=Studies - Facilitators and Barriers to Quitting Smoking=
*See Also: [https://safernicotine.wiki/mediawiki/index.php/Nicotine_-_Misperceptions,_Misinformation,_or_Disinformation Nicotine - Misperceptions, Misinformation, or Disinformation Jump to navigationJump to search]


===[https://vaepworld.com/shareables/ Shareables from VAEP]===
===2021: [https://academic.oup.com/ntr/article-abstract/24/6/855/6440299 Associations Between Nicotine Knowledge and Smoking Cessation Behaviors Among US Adults Who Smoke]===
*This study provides longitudinal evidence that among adult smokers, misperceiving nicotine as a primary cause of smoking-related diseases may be associated with reduced cessation success and lower likelihood of using less harmful nicotine products. These misperceptions may therefore impede efforts to encourage smokers ready to quit to use evidence-based cessation support such as nicotine replacement during quit attempts and limit the success of policies designed to shift smokers to less harmful sources of nicotine.


===2021: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447685/ “It is the One Thing that has Worked”: facilitators and barriers to switching to nicotine salt pod system e-cigarettes among African American and Latinx people who smoke: a content analysis]===
*The majority said they would continue using JUUL to replace cigarettes (83% African American; 94% Latinx) and that JUUL worked better than other methods to reduce cigarettes (72%).
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447685/pdf/12954_2021_Article_543.pdf PDF Version]
*Citation: Pulvers K, Rice M, Ahluwalia JS, Arnold MJ, Marez C, Nollen NL. "It is the One Thing that has Worked": facilitators and barriers to switching to nicotine salt pod system e-cigarettes among African American and Latinx people who smoke: a content analysis. Harm Reduct J. 2021;18(1):98. Published 2021 Sep 16. doi:10.1186/s12954-021-00543-y
*Acknowledgement: This work was supported by the National Institutes of Health [5SC3GM122628]. KP, MR, and NLN were supported in part by 5SC3GM122628. JSA was funded in part by P20GM130414, a NIH funded Center of Biomedical Research Excellence (COBRE).


=Studies=
=Studies - Not Catagorized=
 
=== 2023: [https://pubmed.ncbi.nlm.nih.gov/37148992/ Efficacy and Safety of E-Cigarette Use for Smoking Cessation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.] ===
 
* effectively confirms main findings of Cochrane - though with a somewhat different methodology.
* Results: A total of 5 RCTs (n=3,253) were included. Compared with conventional smoking cessation therapies, the use of nicotine e-cigarettes was associated with an increase in abstinence, defined by the most rigorous criterion of abstinence reported (RR: 1.77; 95% CI: 1.29-2.44). Nicotine e-cigarettes also increased abstinence (defined by the most rigorous criterion) compared to non-nicotine e-cigarettes (RR: 1.56; 95% CI: 1.13-2.15). The incidence of death or SAEs was low across all trials at maximum follow-up.
* Conclusions: Among individuals attempting to quit smoking, nicotine e-cigarettes are more efficacious than conventional nicotine replacement or behavioral smoking cessation therapies and may prove beneficial in reducing smoking-related health risks.
* Note that: RTCs provide very high quality evidence, but that evidence is limited in scope to the trial design. Thus those who take up vaping as an alternative to smoking but with no desire to quit are totally excluded from such results. ''This may be why given the real world evidence from the UK as well as personal testimony of significant numbers of ex-smokers, RTCs seem to underestimate quit rates seen in the real world'' (ed.)


=== 2023: [https://pubmed.ncbi.nlm.nih.gov/37089248/ Biomarkers of Electronic Nicotine Delivery Systems (ENDS) use.] ===
=== 2023: [https://pubmed.ncbi.nlm.nih.gov/37089248/ Biomarkers of Electronic Nicotine Delivery Systems (ENDS) use.] ===
* A useful summary of the current state of biomarker data, with some interesting methodological thoughts thrown in.
* Highlights
* Highlights
** Biomarkers play an essential role in characterizing the health risks of ENDS.
** Biomarkers play an essential role in characterizing the health risks of ENDS.
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** In studies on ENDS, it may be beneficial to use a panel of biomarkers
** In studies on ENDS, it may be beneficial to use a panel of biomarkers
* The biomarker levels of many tobacco-related toxicants measured in biological samples collected from ENDS users did not differ significantly from non-users, except for nicotine metabolites and a small number of biomarkers of exposure to volatile organic compounds and tobacco-specific tobacco nitrosamines. Several studies have shown that while exposed to nicotine, long-term exclusive ENDS users showed significantly lower levels of toxicant biomarkers than cigarette smokers.  
* The biomarker levels of many tobacco-related toxicants measured in biological samples collected from ENDS users did not differ significantly from non-users, except for nicotine metabolites and a small number of biomarkers of exposure to volatile organic compounds and tobacco-specific tobacco nitrosamines. Several studies have shown that while exposed to nicotine, long-term exclusive ENDS users showed significantly lower levels of toxicant biomarkers than cigarette smokers.  
* Goniewicz ML. Addict Neurosci. 2023 Jun;6:100077. doi: 10.1016/j.addicn.2023.100077. Epub 2023 Feb 26. PMID: 37089248
* Goniewicz ML. Addict Neurosci. 2023 Jun;6:100077. doi: 10.1016/j.addicn.2023.100077. Epub 2023 Feb 26. PMID: 3708924
 
===2021: [https://pubmed.ncbi.nlm.nih.gov/34850185/ Associations Between Nicotine Knowledge and Smoking Cessation Behaviors among U.S. Adults Who Smoke]===
<br>
 
 
 
===2021: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447685/ “It is the One Thing that has Worked”: facilitators and barriers to switching to nicotine salt pod system e-cigarettes among African American and Latinx people who smoke: a content analysis]===
*The majority said they would continue using JUUL to replace cigarettes (83% African American; 94% Latinx) and that JUUL worked better than other methods to reduce cigarettes (72%).
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447685/pdf/12954_2021_Article_543.pdf PDF Version]
*Citation: Pulvers K, Rice M, Ahluwalia JS, Arnold MJ, Marez C, Nollen NL. "It is the One Thing that has Worked": facilitators and barriers to switching to nicotine salt pod system e-cigarettes among African American and Latinx people who smoke: a content analysis. Harm Reduct J. 2021;18(1):98. Published 2021 Sep 16. doi:10.1186/s12954-021-00543-y
*Acknowledgement: This work was supported by the National Institutes of Health [5SC3GM122628]. KP, MR, and NLN were supported in part by 5SC3GM122628. JSA was funded in part by P20GM130414, a NIH funded Center of Biomedical Research Excellence (COBRE).




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===2021: [https://aip.scitation.org/doi/10.1063/5.0063593 Modeling the public health impact of e-cigarettes on adolescents and adults]===
===2021: [https://aip.scitation.org/doi/10.1063/5.0063593 Modeling the public health impact of e-cigarettes on adolescents and adults]===
=Shareables=
===[https://docs.google.com/document/d/13-D2q1P0KpmZuoFBkKV4l9wUEQ-zcHfp6MAVJGoAaG4/edit?usp=sharing INNCO: Myth of the month: Ecigs and snus don’t help smokers quit]===
*Each statement on this doc complies with the character limits on twitter. Feel free to copy/paste them into tweets.
===[https://vaepworld.com/shareables/ Shareables from VAEP]===


=Suggested Studies to add to this page=
=Suggested Studies to add to this page=
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